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Undruggable? Or Just Undrugged?

To Drug the Undruggables, First Think the Unthinkable

By Anette Breindl
Science Editor

Tuesday, May 29, 2012

The statistic showing that more than one-third of currently marketed drugs target G-protein coupled receptors is often quoted as evidence that those receptors make good drug targets. And they do. But such convergence is also evidence that although drug discovery is a vast endeavor, in some ways it could be described as a mile wide and an inch deep.

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