• Medsphere Systems (Aliso Viejo, California) reported the open-source release of OpenVista clinical information system (CIS) version 1.0 Beta and OpenVista Server version 1.5.86. Available for download at www.medsphere.org, these applications make up Medspheres Open Source electronic health record (EHR) system. The company said OpenVista CIS provides a multi-platform (Linux and Windows), user-friendly and intuitive client interface through which clinicians can enter and view patient information. OpenVista also is available under a commercial license as part of Medspheres commercial Open Source business model. Medsphere Systems makes open-source healthcare IT solutions.

• Sirtex (Wilmington, Massachusetts) reported the start of an international clinical study evaluating the safety and efficacy of SIR-Spheres microspheres when administered with FOLFOX6 as a first-line therapy in patients with non-resectable colorectal liver metastases compared to chemotherapy alone. Selective Internal Radiation (SIR) therapy is a treatment for inoperable liver cancer that delivers high doses of radiation directly to the site of tumors. In a minimally-invasive treatment, millions of radioactive SIR-Spheres microspheres are infused via a catheter into the liver where they selectively target liver tumors with a dose of internal radiation up to 40 times higher than conventional radiotherapy, while sparing healthy tissue. Sirtex makes cancer therapies.

• Uroplasty (Minneapolis) reported results from the OrBIT trial of its Urgent PC system. The Urgent PC system is aminimally invasive percutaneous tibial nerve stimulation (PTNS) device designed for office-based treatment of urinary urgency, urinary frequency and urge incontinence, symptoms often associated with overactive bladder. The results confirm that Urgent PCs PTNS reduces the incidence of voiding episodes at a rate comparable to tolterodine LA, known by the trade name Detrol LA, the leading pharmaceutical therapy for OAB. Uroplasty makes products for the treatment of voiding dysfunction.