Science

• In Zoonomia project, evolutionary lens hones search for functional genomic variants

  Genetic/Congenital

  A base-by-base comparison of the genome sequences of 240 species of mammals has pinpointed sites in the human genome where mutations are likely to cause disease. The sites are all perfectly conserved across the mammalian family tree over 100...

• Biocom 2023: There’s science going on 250 miles above your head

  Analysis and data insight

  Performing experiments and potentially manufacturing products in space offers some unique advantages in a near-zero gravity environment. Space changes buoyancy, hydrostatic pressure and convective heat flow. Researchers are studying how those...

• Nanomaterial allows location-specific fat targeting

  Clinical

  The positively charged nanoparticle polyamidoamine generation 3 (P-G3) can be specifically targeted to either visceral or subcutaneous fat, and affects both types of fat in different ways, researchers from Columbia University reported in two...

• Amyloid plaques recast as cause of neural network dysfunction

  Neurology/Psychiatric

  Researchers have identified a link between amyloid plaques and dysfunctional neuronal conduction in animal models of Alzheimer’s disease (AD). Their study, which was published in the Dec. 1, 2022, issue of Nature, suggests new ways to think about...

• Innate immunity can drive radiation-induced abscopal effect

  Clinical

  A combination of radiation therapy and CD47 blockade induced an abscopal effect in animal studies even in animals that lacked T cells, researchers reported in the Nov. 21, 2022, online issue of Nature Cancer.

• ENA 2022: Mutant specific or target selective, that is the question for drug development

  Conferences

  Diwali, the Festival of Light, marks different events depending on where it is celebrated. In some areas of India, it marks the return of Lord Rama to his birthplace of Ayodhya after defeating the demon Ravana.