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BioWorld - Sunday, May 22, 2022
Home » Topics » Cancer, BioWorld Asia

Cancer, BioWorld Asia
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China U.S. deal

Merck acquires global rights to cancer drug from Kelun in $1.4B deal

May 17, 2022
By Doris Yu
No Comments
In a deal potentially worth more than $1.4 billion, Sichuan Kelun Pharmaceutical Co. Ltd. has out-licensed a large molecule drug in cancer to Merck & Co. Inc. for development and commercialization outside mainland China, Hong Kong, Macao, and Taiwan.
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Concept of business partnership

Taiho goes Pearl diving, brings up $405M Cullinan deal

May 17, 2022
By Randy Osborne
No Comments
Cullinan Oncology Inc.’s lead program deal with Otsuka Holdings Co. Ltd. subsidiary Taiho Pharmaceutical Co. Ltd. brings $275 million up front and the potential for as much as $130 million in regulatory milestone payments.
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Oral medication

Orion picks up rights to Jemincare non-opioid pain drug in €15M deal

May 17, 2022
By Doris Yu
No Comments
Orion Corp. has secured exclusive global rights, outside China, to a non-opioid pain drug candidate from Jiangxi Jemincare Group Co. Ltd. The deal, for oral sodium channel inhibitor JMKX-000623, brought Jemincare €15 million (US$15.6 million) up front. 
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Cancer cells being destroyed by immunotherapy

The trouble with TIGITs: Genentech’s failure sparks worry across class

May 17, 2022
By Lee Landenberger
No Comments
A phase III failure for Roche Holding AG unit Genentech Inc.'s anti-TIGIT immunotherapy tiragolumab dragged down the share value of several other class entrants. 
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Breast cancer illustration
ESMO Breast Cancer 2022

Taking aim at tumor metabolism, while taming toxicity

May 10, 2022
By Anette Breindl
No Comments
There are 40 years of history behind the development of phosphoinositide 3-kinase (PI3K) inhibitors, Rebecca Dent told her audience at ESMO Breast Cancer 2022. And there have been success stories. There are five FDA-approved PI3K inhibitors in several cancer types, and in April, the FDA approved Vijoice (alpelisib; Novartis AG) for PIK3CA-related overgrowth spectrum, a rare disorder resulting from germline mutations of PIK3CA.
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Antibodies attacking cancer cell

Askgene’s series A adds $20M for cytokine fusion, antibody pipeline

May 10, 2022
By Jennifer Boggs
No Comments
Askgene Pharma Inc., which less than two weeks ago reported positive initial data from an ongoing phase I/II trial testing its claudin 18.2-targeting candidate, ASKB-589, added $20 million in a series A round, intended to advance the company’s clinical pipeline and support further development of its Smartkine cytokine drug platform.
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As space muscles up, Wall Street tries to separate the menin from the noise

May 10, 2022
By Randy Osborne
No Comments
As the American Society of Clinical Oncology meeting nears, presenters are talking up their prospects, including Biomea Fusion Inc. with early data from experiments testing BMF-219, an oral, irreversible covalent menin inhibitor – one in an intriguing class that has sparked efforts by various developers.
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Juniper acquires infigratinib rights from Helsinn in emerging markets

May 10, 2022
By David Ho
No Comments
Juniper Biologics Pte. Ltd. has added another candidate to its pipeline in the space of less than a month. In the latest deal, the Singapore-based company inked an exclusive licensing agreement with Switzerland’s Helsinn Healthcare SA, gaining rights to develop and commercialize oncology drug infigratinib in Australia, New Zealand, Southeast Asia and certain markets in the Middle East and Africa.
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China in red on globe

Hansoh wins greater China rights to oncology drug from Nikang in $218M deal

May 10, 2022
By Doris Yu
No Comments
Hansoh Pharmaceutical Group Co. Ltd. has acquired greater China rights to oncology candidate NKT-2152 from Nikang Therapeutics Inc. in a deal worth up to $218 million. Jiangsu, China-based Hansoh picked up exclusive rights to develop and commercialize the candidate in mainland China, Hong Kong, Macau and Taiwan. In turn, Nikang is eligible to receive $15 million up-front cash payment, as well as up to $203 million in potential development, regulatory and sales-based milestone payments, and tiered royalties.
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Esophageal cancer

Beigene’s tislelizumab meets primary survival endpoint in first-line advanced esophageal cancer

May 10, 2022
By Tamra Sami
No Comments
Beigene Ltd. reported that its global phase III trial of PD-1 inhibitor tislelizumab in combination with chemotherapy met the primary endpoint of overall survival in first-line advanced esophageal cancer.
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