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BioWorld - Sunday, October 1, 2023
Home » Topics » Cancer, BioWorld Asia

Cancer, BioWorld Asia
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RNA strand

Immorna nets $100M in two financing rounds to develop RNA therapies

March 7, 2023
By Doris Yu
No Comments
Immorna Biotechnology Co. Ltd. raised nearly $100 million in series A+ and A++ financing rounds to speed up the clinical development and commercialization of its RNA-based therapeutics. Founded in 2019, Immorna develops therapeutics and vaccines based on its RNA platforms, including conventional, self-replicating and circular RNA.
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Biocytogen out-licenses bispecific antibody to Chipscreen in ¥596M deal

Feb. 28, 2023
By Doris Yu
No Comments
Biocytogen Pharmaceuticals Co. Ltd.’s wholly owned subsidiary, Eucure Biopharma Co. Ltd., licensed exclusive greater China rights to YH-008 to Chipscreen Biosciences Co. Ltd. in a ¥596 million (US$86 million) deal. Chipscreen subsidiary, Chipscreen Newway Biosciences Co. Ltd., will develop and commercialize the bispecific antibody in mainland China, Hong Kong, Macau and Taiwan.
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Fusion raises $60M to acquire phase II radiopharma asset targeting prostate cancer

Feb. 28, 2023
By Tamra Sami
No Comments
Radiopharmaceutical company Fusion Pharmaceuticals Inc. is acquiring a phase II actinium-based alpha-emitter radiopharma program for prostate cancer from Radiomedix Inc.
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Antibody-drug conjugate illustration

Astrazeneca gets global rights to Claudin 18.2 ADC from Lepu, Keymed in $1.2B deal

Feb. 28, 2023
By Doris Yu
No Comments
Indicating its continuing strategy to invest in antibody-drug conjugates (ADCs), Astrazeneca plc obtained exclusive global rights to Claudin 18.2 ADC CMG-901 from Keymed Biosciences Inc. and Lepu Biopharma Co. Ltd. in a deal worth up to $1.163 billion.
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Yen-Yuan symbols

Transthera raises $38M, propelling TT-0420 toward market

Feb. 28, 2023
By Doris Yu
No Comments
Transthera Sciences Inc., a Nanjing, China-based company developing small-molecule therapies in cancer, inflammation and cardiovascular disease, raised ¥260 million (US$38 million) in a series D+ funding round to advance its first drug product.
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Harbour, Cullinan ink $600M+ bispecific antibody agreement

Feb. 14, 2023
By Doris Yu
No Comments
Harbour Biomed Holdings Ltd. licensed exclusive U.S. rights to B7H4 x 4-1BB bispecific immune activator HBM-7008 to Cullinan Oncology Inc. in a deal worth up to $625 million. China-based Harbour will obtain a $25 million up-front payment and is eligible to receive up to $600 million in development, regulatory and sales-based milestones, as well as tiered royalties of up to 20% on U.S. commercial sales.
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Deal illustration

Hengrui licenses EZH2 inhibitor to Treeline in $700M deal

Feb. 14, 2023
By Zhang Mengying
No Comments
Hengrui Pharmaceuticals Co. Ltd. licensed its EZH2 inhibitor, SHR-2554, to Treeline Biosciences Inc. in a deal worth more than $700 million. Treeline will be granted worldwide exclusive rights to the lymphoma drug, except for greater China, in exchange for an up-front payment of $11 million, development milestone payments of up to $45 million, and milestone payments of up to $650 million based on annual net sales once commercialization begins.
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Global handshake silhouette

After Padcev, Corbus ‘Nectin’ line? Potential $692M-plus CSPC deal brings phase I prospect aboard

Feb. 14, 2023
By Randy Osborne
No Comments
Corbus Pharmaceuticals Holdings Inc. signed a back end-loaded licensing deal worth up to $692.5 million with CSPC Megalith Biopharmaceutical Co. Ltd, a subsidiary of CSPC Pharmaceutical Group Ltd., for the latter’s Nectin-4-targeting antibody-drug conjugate CRB-701 (SYS-6002).
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IPO money

South Korea’s GI Innovation to raise up to $34M in IPO on the Kosdaq exchange

Feb. 14, 2023
By Tamra Sami
No Comments
South Korea’s GI Innovation Inc. announced its IPO on the Kosdaq market with plans to raise up to $34 million in March 2023. Funds raised from the IPO will go toward phase I/II clinical trials of immunotherapy agent GI-101 in the U.S. and Korea, and a phase I trial of allergy treatment GI-301 (also known as YH-35324) in Korea.
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Sirnaomics seeks FDA guidance for late-stage skin cancer candidate

Feb. 7, 2023
By Caroline Richards
No Comments
Sirnaomics Ltd. is gearing up to start either an expanded phase IIb or a phase III clinical trial for its lead siRNA candidate, STP-705, for the treatment of two non-melanoma skin cancers: squamous cell carcinoma in situ and basal cell carcinoma.
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