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BioWorld - Thursday, September 28, 2023
Home » Topics » Cancer, BioWorld Asia

Cancer, BioWorld Asia
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ASCO 2023: AI has little fad to it and a personalized future

June 6, 2023
By Lee Landenberger
No Comments
Despite the title of the Sunday, June 4 lead-off presentation at the American Society of Clinical Oncology (ASCO) meeting in Chicago, there was little room left for doubt about the increasingly important place of artificial intelligence (AI) in drug development.
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Handshake behind digital globe

In $392M deal, C4 and Betta partner in China on preclinical NSCLC drug

June 6, 2023
By Karen Carey
No Comments
In a deal potentially worth $392 million, C4 Therapeutics Inc. signed with Betta Pharmaceuticals Co. Ltd. to develop and market an orally bioavailable BiDAC degrader for non-small-cell lung cancer (NSCLC).
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Australian coins and bills

Immutep to raise AU$80M to advance LAG-3 immunotherapy pipeline

June 6, 2023
By Tamra Sami
No Comments
Immutep Ltd. announced an AU$80 million (US$52.1 million) capital raise that consists of a AU$50 million placement and a AU$30 million entitlement offer to eligible shareholders to fund clinical programs for lead candidate eftilagimod (IMP-321, efti), a lymphocyte activation gene-3 (LAG-3) fusion protein and major histocompatibility complex class II agonist that stimulates both innate and adaptive immunity for treating cancer.
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Cancer cells

Bayer’s PI3K inhibitor cleared in China for follicular lymphoma

May 30, 2023
By Doris Yu
No Comments
Bayer AG’s copanlisib was approved in China for the treatment of adult patients with relapsed follicular lymphoma who have received at least two prior systemic therapies. It is the first indication approved in the country for copanlisib, which is entering a market with room to grow but marked by some domestic competition.
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Huang Baohua, founder and CEO, Coherent Biopharma

Coherent Biopharma nets $100M in financing for Bi-XDC drugs

May 23, 2023
By Doris Yu
No Comments
Coherent Biopharma Co. Ltd. raised $100 million in series B and B+ financing rounds to step up its efforts to develop its bi-targeting ligand-drug conjugate (Bi-XDC) drugs and get them to market. Suzhou, China-based Coherent plans to use its newly expanded war chest to support the clinical trials of three candidates, CBP-1008, CBP-1018 and CBP-1019, as well as an IND application for CBP-8008 in China and the U.S., the company told BioWorld.
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3D illustration demonstrating antibody-drug conjugate.

Lanova licenses ADC candidate for MM to Astrazeneca in $600M deal

May 16, 2023
By Zhang Mengying
No Comments
In a deal worth as much as $600 million, Lanova Medicines Ltd. licensed exclusive global rights to Astrazeneca plc for LM-305, an antibody-drug conjugate (ADC) targeting GPRC5D, for multiple myeloma (MM). Lanova will receive up-front and near-term payments of up to $55 million and development and commercial milestone payments of up to $545 million, as well as tiered royalties on net sales worldwide.
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CBMG licenses CAR T therapies to Janssen in a $245M deal

May 9, 2023
By Zhang Mengying
No Comments
Cellular Biomedicine Group Inc. (CBMG) licensed a pair of candidates for the treatment of non-Hodgkin lymphoma to Janssen Biotech Inc. for development outside of greater China. The candidates are anti-CD19 and CD20 bispecific CAR T-cell therapy C-CAR039 and anti-CD20 CAR T-cell therapy C-CAR066.
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Global handshake silhouette

In the ADC race, Eisai and Bliss enter one of the year’s biggest deals

May 9, 2023
By Lee Landenberger
No Comments
In the latest deal from the burgeoning antibody-drug conjugate (ADC) space, Eisai Co. Ltd. and privately held Bliss Biopharmaceutical (Hangzhou) Co. Ltd. reached a development and commercialization agreement that could be worth up to $2 billion. The massive collaboration is the eighth largest so far this year and one of three that involve ADCs in the year’s top 10 deals.
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Breast cancer illustration

Zion Pharma in $680M Roche deal for its HER2 breast cancer drug

May 9, 2023
By Karen Carey
No Comments
Roche AG acquired global rights to Zion Pharma Ltd.’s lead program, ZN-A-1041, an orally administered selective tyrosine kinase inhibitor that is designed to penetrate the blood-brain barrier and can prevent and treat brain metastases in HER2-positive metastatic breast cancer patients.
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Clinical data illustration

Junshi’s anti-PD-1 drug meets primary endpoints in phase III study for NSCLC

April 25, 2023
By Doris Yu
No Comments
Shanghai Junshi Biosciences Co. Ltd.’s anti-PD-1 monoclonal antibody toripalimab showed positive interim event-free survival (EFS) results in a phase III study to treat patients with resectable non-small-cell lung cancer (NSCLC). This is the world’s first phase III trial that shows perioperative treatment with an anti-PD-1 monoclonal antibody significantly extends EFS of patients with resectable NSCLC, according to Shanghai-based Junshi Biosciences.
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