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BioWorld - Thursday, June 11, 2026
Home » Topics » Clinical

Clinical
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3D illustration of a nerve cell

Sanofi phase III CIDP quit dents Dianthus; C1 mismatch?

June 10, 2026
By Randy Osborne
No Comments
Investors in Dianthus Therapeutics Inc. apparently chose to ignore subtleties in the difference between efforts with that firm’s claseprubart vs. those by competitor Sanofi SA, which said that the phase III Mobilize study testing riliprubart in chronic inflammatory demyelinating polyneuropathy (CIDP) will be stopped for futility.
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Gastric cancer

Innovent submits NDA for CLDN18.2 ADC for gastric cancer

June 9, 2026
By Tamra Sami
No Comments
Innovent Biologics Co. Ltd.’s Claudin18.2-targeted antibody-drug conjugate (ADC), arcotatug tavatecan (IBI-343, TAK-921), met the primary endpoint in the international multicenter phase III G-Hope-001 trial in advanced gastric cancer, according to interim results.
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China compass

ASCO 2026: Chinese biopharma arrives at ASCO with pivotal wins

June 9, 2026
By Tamra Sami
No Comments
If the 2026 American Society of Clinical Oncology (ASCO) annual meeting in Chicago from May 30 to June 3 demonstrated anything about the evolution of China’s biotechnology sector, it was that the industry’s center of gravity is shifting. While Chinese companies once relied heavily on PD-1 antibodies and licensing deals to gain international visibility, this year’s oral presentations showcased a broader innovation base.
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Close-up of injector pen in hands

GLP-1s and more weigh in at ADA

June 9, 2026
By Brian Orelli
No Comments
GLP-1 receptor agonists remained center stage at the 2026 Scientific Sessions of the American Diabetes Association with Boehringer Ingelheim GmbH and Astrazeneca plc, joining the leaders, Eli Lilly and Co. and Novo Nordisk A/S, in presenting data for their respective GLP-1 drugs.
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Pancreatic cancer anatomy

Clinical footwork pays off in Tango’s PDAC combo phase I/II

June 8, 2026
By Randy Osborne
No Comments
Tango Therapeutics Inc. will be sitting down with the U.S. FDA soon to discuss pivotal work ahead based on what Cantor analyst Eric Schmidt called “amazing” data from the phase I/II study of vopimetostat, a PRMT5 inhibitor, paired with Revolution Medicines Inc.’s RAS(ON) inhibitors in patients with MTAP-deleted and RAS-mutant metastatic pancreatic ductal adenocarcinoma (PDAC) as well as non-small cell lung cancer.
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China compass

ASCO 2026: Chinese biopharma arrives at ASCO with pivotal wins

June 5, 2026
By Tamra Sami
No Comments
If the 2026 American Society of Clinical Oncology (ASCO) annual meeting in Chicago from May 30 to June 3 demonstrated anything about the evolution of China’s biotechnology sector, it was that the industry’s center of gravity is shifting. While Chinese companies once relied heavily on PD-1 antibodies and licensing deals to gain international visibility, this year’s oral presentations showcased a broader innovation base.
Read More
Swab sample and patient

Roche develops PCR test to detect the Ebola Bundibugyo virus

June 5, 2026
By Shani Alexander
No Comments
Roche Holding AG has rapidly developed a research-use only molecular PCR test to detect the rare Ebola Bundibugyo virus, to support response efforts amid the ongoing outbreak in the Democratic Republic of Congo and Uganda. The test comes as commentary in The Lancet this week underscored the urgent need for a fit-for-purpose diagnostic test, as it warned that the absence of reliable testing is hampering efforts to ascertain the scale of the epidemic and understand the transmissibility of this strain of Bundibugyo virus.
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3D dollar sign

Ona raises $86.6M series B for ADCs to treat advanced cancers

June 4, 2026
By Nuala Moran
No Comments
Antibody-drug conjugate (ADC) specialist Ona Therapeutics SL has closed an oversubscribed series B at $86.6 million, as clinical development of the lead program ONA-255 in advanced treatment-resistant breast cancer gathers steam.
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Woman taking medication for mental illness

Autobahn on the fast track with bipolar thyroid agonist

June 4, 2026
By Karen Carey
No Comments
Achieving high marks in the phase II Amplify-BD trial for bipolar I and II depression, Autobahn Therapeutics Inc.’s elunetirom, a brain-penetrant central nervous system thyroid hormone receptor agonist, or thyromimetic, is moving toward a registrational path and a clinical readout in major depressive disorder.
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Gastric cancer

Innovent submits NDA for CLDN18.2 ADC for gastric cancer

June 4, 2026
By Tamra Sami
No Comments
Innovent Biologics Co. Ltd.’s Claudin18.2-targeted antibody-drug conjugate (ADC), arcotatug tavatecan (IBI-343, TAK-921), met the primary endpoint in the international multicenter phase III G-Hope-001 trial in advanced gastric cancer, according to interim results.
Read More
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