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BioWorld - Friday, February 26, 2021
Home » Authors » Nuala Moran

Nuala Moran

Articles

ARTICLES

Real world data show vaccines are cutting risk of severe COVID-19, hospitalizations

Feb. 22, 2021
By Nuala Moran
No Comments
LONDON – The first population-level real world data on COVID-19 vaccines indicate they are having a dramatic impact on severe disease, with a study in Scotland showing a fall of 85% in hospital admissions for people who received the Pfizer Inc./Biontech SE product, and a drop of 94% for those who had Astrazeneca plc’s vaccine, four weeks after receiving the first dose.
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Liver illustration
Bettering bile

New organoid marks progress to liver repair beyond hepatocytes

Feb. 22, 2021
By Nuala Moran
No Comments
Organoids grown from cholangiocytes – the epithelial cells of the bile duct – are poised to be used in ex vivo cell therapy to increase the number of donated livers that are suitable for transplant, and also for direct bile duct repairs. The organoids have been shown to be effective in correcting defects in mouse models and in perfused donated livers. They are now being tested in large animal models.
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Hand holding gear, dollar sign

Evox’s exosome platform draws new investors in $95.4M series C

Feb. 18, 2021
By Nuala Moran
No Comments
LONDON – Exosome specialist Evox Therapeutics Ltd. has raised $95.4 million in a series C round that will enable it to progress a number of rare disease programs into the clinic, with the lead due to enter phase I at the beginning of next year.
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Advent collaborating with HDI in $215M dual fund for early stage research

Feb. 18, 2021
By Nuala Moran
No Comments
LONDON – Advent Life Sciences announced the close of two new transatlantic funds with a total of $215 million, to be dedicated to seed and series A funding of early stage science. The first fund is Advent’s own Life Sciences fund III, while the second is the Advent-Harrington Impact fund, which London-based Advent has raised, and will manage, on behalf of the Harrington Discovery Institute of Cleveland.
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Liver illustration
Bettering bile

New organoid marks progress to liver repair beyond hepatocytes

Feb. 18, 2021
By Nuala Moran
No Comments
Organoids grown from cholangiocytes – the epithelial cells of the bile duct – are poised to be used in ex vivo cell therapy to increase the number of donated livers that are suitable for transplant, and also for direct bile duct repairs.
Read More
Europe under magnifier/petri dish with coronavirus

Europe chases COVID-19 variants, updates strategies

Feb. 17, 2021
By Nuala Moran
No Comments
LONDON – The EU is taking concerted action to detect new variants of SARS-CoV-2, investing €225 million (US$270 million) to increase viral genome sequencing to 5% of positive cases across Europe, and to carry out research on their evolution and transmissibility.
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RoActemra

Recovery trial shows Roactemra’s benefit in hospitalized COVID-19 patients

Feb. 11, 2021
By Nuala Moran
No Comments
LONDON – After a number of equivocal small studies, the U.K. Recovery trial has applied its heft to turn in statistically significant evidence that the rheumatoid arthritis treatment Roactemra (tocilizumab) reduces mortality in hospitalized COVID-19 patients.
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COVID-19 vaccines should be tested against variants, EMA says

Feb. 11, 2021
By Nuala Moran
No Comments
LONDON – The EMA has requested all COVID-19 vaccine developers to investigate if their products offer protection against new variants of SARS-CoV-2 and to submit the relevant data.
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United Kingdom flag, map

Post-Brexit med-tech legislation takes on life of its own in U.K.

Feb. 10, 2021
By Nuala Moran
No Comments
LONDON – It began life as a legal tidy-up of post-Brexit regulatory issues, but the Medicines and Medical Devices bill that emerged from its final reading last week is in a significantly different form. Most notably, the bill legislates for the creation of a national register of all implantable medical devices and the appointment of a patient safety commissioner to act a single port of call and advocate for patients when devices fail.
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WHO COVID-19 origins press conference

Intermediary host species likely introduced SARS-CoV-2 virus, says WHO

Feb. 9, 2021
By Nuala Moran
No Comments
LONDON – The World Health Organization’s (WHO) mission to Wuhan has rejected accidental laboratory escape as the source of the SARS-CoV-2 pandemic, but failed to uncover satisfactory evidence of its exact origin.
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View All Articles by Nuala Moran

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