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Home » Topics » Regulatory » Patents

Patents
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Edwards seeks to add three months to Ultra Resilia patent

July 9, 2025
By Mark McCarty
The U.S. FDA noted in a series of Federal Register declarations that several device makers are working with the Patent and Trademark Office to claim regulatory review times for their devices, including the Sapien 3 Ultra Resilia device by Edwards Lifesciences Corp.
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IMEC ingestible GI sensor
Patents

IMEC seeks ingestible GI sensor patent

July 9, 2025
By Simon Kerton
Researchers from IMEC, the Netherlands’ OnePlanet Research Center in Wageningen, filed for protection of an inexpensive, highly miniaturized ingestible device that may be used for remotely activatable sampling, gut health monitoring and drug delivery.
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Endocrine/metabolic

Guangdong Zhongsheng Ruichuang Pharmaceutical discovers new GLP-1R agonists

July 9, 2025
Guangdong Zhongsheng Ruichuang Pharmaceutical Co. Ltd. has described glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of type 2 diabetes, obesity, atherosclerosis, nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), hyperglycemia, cerebral infarction, hypertension and Parkinson’s disease.
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Neurology/psychiatric

New EPHX2 inhibitors disclosed in Roche patent

July 9, 2025
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have divulged bifunctional epoxide hydrolase 2 (EPHX2; sEH) inhibitors reported to be useful for the treatment of pain, diabetic retinopathy and neurodegeneration. An exemplified compound (Ex 23 pg 78, claim 18) inhibited human sEH activity (IC50=0.5 nM) using Rapidfire mass spectrometry (RFMS) assays (WO 2025125135).
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Infection

Latvian Institute of Organic Synthesis describes new PfSUB1 inhibitors for malaria

July 9, 2025
Latvian Institute of Organic Synthesis has identified subtilisin-like protease 1 (PfSUB1) (Plasmodium falciparum) inhibitors reported to be useful for the treatment of malaria.
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Neurology/psychiatric

Idorsia Pharmaceuticals divulges new orexin OX2 receptor agonists

July 9, 2025
Idorsia Pharmaceuticals Ltd. has synthesized aryl sulfone and sulfanone derivatives acting as orexin OX2 receptor agonists reported to be useful for the treatment of eating disorders, fatigue, Kleine-Levin syndrome, narcolepsy, obesity, pain, and psychiatric and inflammatory disorders, among others.
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Inflammatory

Lilly and Evotec patent new ROCK2 inhibitors

July 9, 2025
Eli Lilly & Co. and Evotec International GmbH have disclosed Rho-associated protein kinase 2 (ROCK2) inhibitors reported to be useful for the treatment of cancer, autoimmune disease, fibrosis, and inflammatory and neurological disorders.
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Neurology/psychiatric

Grünenthal discovers new Nav1.8 blockers

July 8, 2025
Grünenthal GmbH has described sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for the treatment of pain.
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Neurology/psychiatric

Ferroptosis inhibitors for mitochondrial disease disclosed in Acurex patent

July 8, 2025
Acurex Biosciences Corp. has divulged fused quinone compounds acting as ferroptosis inhibitors reported to be useful for the treatment of mitochondrial disease.
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Cancer

Deciphera Pharmaceuticals describes new PIK3C3 inhibitors

July 8, 2025
Deciphera Pharmaceuticals LLC has identified phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3; Vps34) inhibitors reported to be useful for the treatment of cancer.
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