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BioWorld - Friday, December 5, 2025
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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Brain and financial charts
Index insights

Minerva jumps on phase III funding, leading neuro stocks

Dec. 4, 2025
By Amanda Lanier
No Comments
The BioWorld Neurological Diseases Index continued the recovery noted at the end of August, closing November with a gain of 2.64%.
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Cobenfy

Florida key to BMS slip in ADP? Acadia sails ahead

Dec. 4, 2025
By Randy Osborne
No Comments
Drug developers big and small are pursuing a solution for the curse of psychosis that occurs along with the already tragic diagnosis of Alzheimer’s disease, an affliction known as ADP.
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Novo Nordisk semaglutide pill

CTAD 2025: Diagnosing semaglutide’s failure in Alzheimer’s trials

Dec. 4, 2025
By Brian Orelli
No Comments
A little over a week after announcing that the Evoke and Evoke+ studies failed to show that oral semaglutide could slow cognition decline in patients with Alzheimer’s disease, investors and researchers got the first look at the actual data from the studies, which were presented at the Clinical Trials on Alzheimer’s Disease 2025 meeting.
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Axogen Avance Nerve Graft

Axogen's Avance secures FDA approval for nerve repair

Dec. 4, 2025
By Annette Boyle
The U.S. FDA granted accelerated approval for the Biologics License Application for Axogen Inc.'s Avance, an acellular nerve allograft that serves as a scaffold for nerve regrowth, for treatment of patients with sensory, mixed and motor peripheral nerve discontinuities. The company expects Avance to be commercially available in the second quarter of 2026.
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Evoke SCS system

Saluda to expand spinal cord stimulation market in AU$231M IPO

Dec. 4, 2025
By Tamra Sami
Saluda Medical Pty Ltd. announced a AU$231 million ($152.7 million) initial public offering on the Australian Securities Exchange to scale up its U.S. footprint for its Evoke spinal cord simulation system for chronic pain.
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Illustration of head with maze that is missing parts
Neurology/psychiatric

CTAD 2025: The challenges of combination therapies for dementia

Dec. 4, 2025
By Brian Orelli
No Comments
At the Clinical Trials on Alzheimer’s Disease 2025 meeting, a panel of experts discussed the need for developing combination therapies for the complex diseases that result in Alzheimer's disease and other dementias.
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Neurology/psychiatric

Genescience discovers new salts of MC4 receptor antagonists

Dec. 4, 2025
Genescience Pharmaceuticals Co. Ltd. has described salts of known melanocortin MC4 receptor antagonists reported to be useful for the treatment of anorexia nervosa, cachexia, muscle atrophy, nausea and vomiting, sarcopenia, anxiety, bone disorders and inflammatory disorders.
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Neurology/psychiatric

ARV-102 targets LRRK2 to prevent neurodegeneration

Dec. 4, 2025
No Comments
LRRK2 plays a key role in the biology of multiple neurodegenerative disorders, including Parkinson’s disease (PD) and progressive supranuclear palsy (PSP), where mutations or altered activity are associated with impaired cellular signaling and neuronal decline.
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Illustration of DNA double helix and motorized wheel chair
Neurology/psychiatric

Arrakis reports preclinical progress of rSM program to treat DM1

Dec. 4, 2025
No Comments
Arrakis Therapeutics Inc. has announced the presentation of preclinical data demonstrating the progress of its RNA-targeted small molecule (rSM) drug program for the treatment of myotonic dystrophy type 1 (DM1).
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Illustration of head with maze that is missing parts

CTAD 2025: The challenges of combination therapies for dementia

Dec. 3, 2025
By Brian Orelli
No Comments
At the Clinical Trials on Alzheimer’s Disease 2025 meeting, a panel of experts discussed the need for developing combination therapies for the complex diseases that result in Alzheimer's disease and other dementias.
Read More
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