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BioWorld - Monday, May 16, 2022
Home » Authors » Randy Osborne

Randy Osborne

Articles

ARTICLES

Summer stock: Atara shares await July review of phase II MS trial

May 13, 2022
By Randy Osborne
No Comments
As the six-month interim analysis of phase II data for ATA-199 in progressive forms of multiple sclerosis (MS) nears, investors in Atara Biotherapeutics Inc. – not to mention patients – are growing more intrigued by the prospect, an off-the-shelf T-cell candidate that targets Epstein Barr virus-infected B cells and plasma cells in the central nervous system.
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Taiho goes Pearl diving, brings up $405M Cullinan deal

May 12, 2022
By Randy Osborne
No Comments
Cullinan Oncology Inc.’s lead program deal with Otsuka Holdings Co. Ltd. subsidiary Taiho Pharmaceutical Co. Ltd. brings $275 million up front and the potential for as much as $130 million in regulatory milestone payments.
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Pamela Conley, CEO, Nuvig
Newco news

‘Stable’ door opens for Nuvig as $47M series A backs homeostasis bid

May 11, 2022
By Randy Osborne
No Comments
Nuvig Therapeutics Inc. emerged from stealth mode with a $47 million series A round to back efforts to develop drugs that induce immune homeostasis as a way of treating autoimmune diseases without disturbing the system’s normal function.
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As space muscles up, Wall Street tries to separate the menin from the noise

May 10, 2022
By Randy Osborne
No Comments
As the American Society of Clinical Oncology meeting nears, presenters are talking up their prospects, including Biomea Fusion Inc. with early data from experiments testing BMF-219, an oral, irreversible covalent menin inhibitor – one in an intriguing class that has sparked efforts by various developers.
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Pills shaded in psychedelic colors

Wall Street less Leary of psychedelics as field mushrooms

May 10, 2022
By Randy Osborne
No Comments
Not long ago, people who touted the prospects of psychedelic drugs might have been accused of hallucinating, but in the U.S. and elsewhere the space has expanded in recent years, as mental health treatments remain “stuck where cancer was 50 years ago,” said Roth analyst Elemer Piros.
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Brain illustration

CGRPs on the ascent in migraine, Pfizer paying $11.6B for Biohaven

May 10, 2022
By Randy Osborne
No Comments
Pfizer Inc. is taking over Biohaven Pharmaceutical Holding Co. Ltd. for $11.6 billion to bring aboard Nurtec ODT (rimegepant), the calcitonin gene-related peptide (CGRP) receptor antagonist first approved in February 2020 for acute migraine in adults with or without aura.
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As space muscles up, Wall Street tries to separate the menin from the noise

May 6, 2022
By Randy Osborne
No Comments
As the American Society of Clinical Oncology meeting nears, presenters are talking up their prospects, including Biomea Fusion Inc. with early data from experiments testing BMF-219, an oral, irreversible covalent menin inhibitor – one in an intriguing class that has sparked efforts by various developers.
Read More
Back and shoulder

As LS tree line rises, Timber stacked for success?

April 29, 2022
By Randy Osborne
No Comments
A handful of developers are advancing drug prospects in the localized scleroderma (LS) space, with candidate mechanisms that range from cell-based gene therapy to IL-4 or IL-6 antagonism to PDE4 blocking, and with efforts that involve approved as well as experimental compounds.
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Fully charged Plexium’s double-A: $565M Abbvie deal in TPD follows Amgen pact

April 28, 2022
By Randy Osborne
No Comments
Targeted protein degradation (TPD) specialist Plexium Inc.’s potential $565 million deal with Abbvie Inc. came on the heels of a tie-up with Amgen Inc. in February worth as much as $500 million-plus, as well as an oversubscribed $102 million financing the same month – all of which translates into “optionality, moving forward, to keep our heads down, do the work we’re really good at and continue to watch the market,” said CEO Percival Barretto-Ko.
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Let it Rain: MDM2 data floodgates to open in year’s second half, space awash with players

April 27, 2022
By Randy Osborne
No Comments
Among the attention-getters at the American Association for Cancer Research meeting April 8-13 was protein-degradation specialist Kymera Therapeutics Inc., which made the preclinical case for its approach in murine double minute 2 (MDM2) research vs. an inhibitor. The MDM2 space has grown increasingly busy in recent years, with large and small biopharma concerns moving ahead with research in all phases of development.
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View All Articles by Randy Osborne

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