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BioWorld - Wednesday, January 21, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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China flag and vial

Six drugs to watch in China for 2026

Jan. 20, 2026
By Tamra Sami
No Comments
As China emerges as a critical commercial market and a source of global innovation, the newly released 2026 edition of Clarivate’s Drugs to Watch report highlights six drugs to watch in the China market for the year ahead.
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Liver over digital lens background

Astrazeneca expands China cell therapy footprint with Abelzeta CAR T

Jan. 20, 2026
By Tamra Sami
No Comments
Astrazeneca plc is paying up to $630 million to acquire China rights to Abelzeta's Pharma Inc.’s C-CAR031 (AZD5851), an autologous glypican 3-targeting CAR T, securing global rights to develop, manufacture and commercialize the CAR T for liver cancer.
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Red dart in center of red target

GSK gaining Rapt’s allergy drug in $2.2B M&A

Jan. 20, 2026
By Karen Carey
No Comments
Offering $2.2 billion for Rapt Therapeutics Inc. and gaining its long-acting lead drug, ozureprubart, for food allergy and other indications, GSK plc is positioning itself to compete with market leader Xolair (omalizumab), developed by Roche AG’s Genentech unit and Novartis AG.
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Art concept for inflamed human tissue
Immune

Highly TYK2-selective inhibitor for inflammatory and autoimmune disorders

Jan. 19, 2026
No Comments
The compound, which showed oral bioavailability of 42.7%, performed similarly well as the licensed drug loratidine in a mouse model of the inflammatory disease allergic rhinitis.
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China flag and vial

Six drugs to watch in China for 2026

Jan. 16, 2026
By Tamra Sami
No Comments
As China emerges as a critical commercial market and a source of global innovation, the newly released 2026 edition of Clarivate’s Drugs to Watch report highlights six drugs to watch in the China market for the year ahead.
Read More
mRNA vaccines are composed of messenger RNA encapsulated in lipid nanoparticles
Infection

Ionizable lipid-based mRNA vaccine protects against S. pneumoniae

Jan. 15, 2026
No Comments
In recent years, messenger RNA (mRNA) vaccines have shown significant success in preventing viral and bacterial infections, as well as in cancer immunotherapy and other disease applications. In particular, the development of lipid nanoparticle (LNP)-encapsulated mRNA has revolutionized vaccine development thanks to several advantages, including elevated immunogenicity, rapid manufacturing and a generally favorable safety profile compared to viral vectors and traditional adjuvant-based vaccines.
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Antibody
Immune

Henlius in-licenses anti-IL-1RAP antibody from U-mab Biopharma

Jan. 15, 2026
No Comments
Shanghai Henlius Biotech Inc. has entered into an exclusive global license agreement with U-mab Biopharma (Lianyungang) Co. Ltd., securing rights to a monoclonal antibody (mAb) targeting interleukin-1 receptor accessory protein (IL-1RAP) for inflammatory and autoimmune diseases.
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Hand holding elbow

Takeda’s zasocitinib meets phase III psoriasis endpoints

Jan. 13, 2026
By Tamra Sami
No Comments
Takeda Pharmaceuticals Co. Ltd.’s oral tyrosine kinase 2 inhibitor, zasocitinib (TAK-279), met the co-primary endpoints and all ranked secondary endpoints in two pivotal phase III studies in patients with moderate to severe plaque psoriasis.
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Hutchmed plans China NDA filing of sovleplenib in rare anemia

Jan. 13, 2026
By Marian (YoonJee) Chu
No Comments
Hutchmed Ltd. plans to file a second NDA in China for sovleplenib, a novel spleen tyrosine kinase inhibitor, based on positive phase II/III findings in warm antibody autoimmune hemolytic anemia.
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Swiss currency
Immune

Tecregen raises seed round to progress thymus-restoring biologics

Jan. 12, 2026
By Nuala Moran
No Comments
Newco Tecregen AG has raised CHF10 million (US$12.5 million) to advance a novel way of regenerating the thymus in order to boost T-cell production and stimulate recovery of the immune system following stem cell transplants and chemo- and radiotherapy.
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