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BioWorld - Saturday, April 11, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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Drug R&D concept image.
Newco news

Kyron-Servier deal focused on programmable glycoprotein platform

March 13, 2026
By Nuala Moran
No Comments
Newco Kyron Bio is showing its colors after sealing a research agreement with Servier SA, underpinning a claim that it has overcome one of the longest-running challenges of the biotech industry, and developing technology to precisely control the glycosylation of therapeutic proteins.
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Illustration of a mast cell releasing histamines
Immune

Enanta Pharmaceuticals presents data for KIT inhibitor EDP-978

March 13, 2026
No Comments
The activation of mast cells in the lungs and skin is involved in diseases such as asthma and chronic spontaneous urticaria, where the KIT receptor tyrosine kinase is a key regulator of mast cell function.
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Illustration showing aqueous humor drainage from the eye
Ocular

Resident macrophages reveal the immune side of glaucoma

March 12, 2026
By Mar de Miguel
No Comments
Scientists at Duke University have uncovered how macrophages help maintain intraocular pressure and have found that a specific type, resident macrophages, is essential for proper drainage of intraocular fluid. When these cells are removed, drainage becomes impaired and intraocular pressure rises, contributing to the development of glaucoma.
Read More
Pregnancy
Immune

Uterus transplants show how immune cells shape pregnancy outcomes

March 12, 2026
By Nuala Moran
No Comments
A study involving a small cohort of women who have received womb transplants has cast fresh light on how the immune system shapes pregnancy outcomes, opening up new avenues of research into implantation failure, preeclampsia and preterm birth. Using an array of single cell analyses, scientists at the University of Alabama at Birmingham (UAB) studied the composition and gene expression profiles of immune cells in tissue samples from five women who had received womb transplants.
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Illustration of inflamed spine

China’s Qyuns moves IL-17 biologic toward first approval

March 11, 2026
By Tamra Sami
No Comments
Qyuns Therapeutics Co. Ltd. has moved closer to its first commercial product after China’s National Medical Products Administration (NMPA) accepted its NDA for IL-17 antibody crusekitug (QX-002N) for treating ankylosing spondylitis (AS), a chronic inflammatory disease that affects the spine and sacroiliac joints.
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Pregnancy

Uterus transplants show how immune cells shape pregnancy outcomes

March 11, 2026
By Nuala Moran
No Comments
A study involving a small cohort of women who have received womb transplants has cast fresh light on how the immune system shapes pregnancy outcomes, opening up new avenues of research into implantation failure, preeclampsia and preterm birth.
Read More
Immune

VAV1 degradation inducers reported in new Humanwell Healthcare patents

March 11, 2026
Humanwell Healthcare (Group) Co. Ltd. has divulged molecular glue degraders comprising cereblon (CRBN)-binding agents acting as proto-oncogene Vav (VAV1) degradation inducers. They are reported to be useful for the treatment of autoimmune disease, cancer, inflammatory bowel disease, multiple sclerosis, myasthenia gravis, periodontitis, psoriasis, rheumatoid arthritis and type I diabetes, among others.
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Skin irritation on hands
Immune

HX-16108 holds promise for treating inflammatory skin diseases

March 11, 2026
No Comments
Atopic dermatitis (AD) is an inflammatory skin disease accompanied by pruritus, for which IL-13 and IL-31 are clinically validated targets. Earendil Labs Inc. has developed a bispecific antibody targeting both IL-13 and IL-31, HX-16108, with an extended half-life.
Read More
Illustration showing aqueous humor drainage from the eye
Ocular

Resident macrophages reveal the immune side of glaucoma

March 11, 2026
By Mar de Miguel
No Comments
Scientists at Duke University have uncovered how macrophages help maintain intraocular pressure and have found that a specific type, resident macrophages, is essential for proper drainage of intraocular fluid. When these cells are removed, drainage becomes impaired and intraocular pressure rises, contributing to the development of glaucoma.
Read More
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