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BioWorld - Monday, December 29, 2025
Home » Topics » Disease categories and therapies » Immune

Immune
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Female scientist looking through microscope
Immuno-oncology

Antengene outlines early-stage pipeline

Nov. 20, 2025
No Comments
Antengene Corp. Ltd. has outlined progress in its early-stage pipeline. The company has leveraged its Antengager T-cell engager (TCE) platform for the discovery of multiple investigational programs.
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Jingsong Wang, CEO, Harbour Biomed
Cancer

Harbour Biomed launches AI-based antibody development platform

Nov. 19, 2025
By Tamra Sami
No Comments
Harbour Biomed is stepping up its antibody discovery process by using AI to develop innovative therapeutics. “We have done great through the traditional way of generating leads and designing molecules, but there’s a major gap as some therapeutics cannot reach the desired location or common targets,” Harbour Biomed founder, chairman and CEO Jingsong Wang told BioWorld.
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Jingsong Wang, CEO, Harbour Biomed

Harbour Biomed launches AI-based antibody development platform

Nov. 18, 2025
By Tamra Sami
No Comments
Harbour Biomed is stepping up its antibody discovery process by using AI to develop innovative therapeutics. “We have done great through the traditional way of generating leads and designing molecules, but there’s a major gap as some therapeutics cannot reach the desired location or common targets,” Harbour Biomed founder, chairman and CEO Jingsong Wang told BioWorld.
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Abstract illustration of pig and human with medical motifs
Nephrology

‘Encyclopedia’ of xenotransplantation reveals drivers of immune rejection

Nov. 18, 2025
By Anette Breindl
No Comments
By transplanting a pig kidney into a brain-dead person, researchers have been able to conduct the first long-term study of the physiological processes occurring in both the transplant recipient and the pig organ for 61 days. The findings were published in the Nov. 14, 2025, issue of Nature in two papers – one focusing on physiological and immunological measurements, the other on multiomics.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 18, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
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Abstract illustration of pig and human with medical motifs
Nephrology

‘Encyclopedia’ of xenotransplantation reveals drivers of immune rejection

Nov. 17, 2025
By Anette Breindl
No Comments
By transplanting a pig kidney into a brain-dead person, researchers have been able to conduct the first long-term study of the physiological processes occurring in both the transplant recipient and the pig organ for 61 days. The findings were published in the Nov. 14, 2025, issue of Nature in two papers – one focusing on physiological and immunological measurements, the other on multiomics.
Read More
Transparent capsule with DNA and cells

Charity bringing to EU market gene therapy spurned by pharma

Nov. 14, 2025
By Nuala Moran
No Comments
Fifteen years since the first patient was treated, and after being ditched by two companies, the EMA is recommending approval of Waskyra (etuvetidigene autotemcel), the first gene therapy for treating Wiskott-Aldrich syndrome.
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Immune

Dual-antigen mRNA vaccine protects against lethal DBV challenge

Nov. 13, 2025
No Comments
Investigators from the University of Science and Technology of China and RNAlfa Biotech have described a novel mRNA-based vaccine candidate against Dabie Banda virus (DBV), which has fatality rates of up to 30% in some East Asian countries.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
Read More
Arthritis pain illustration
Musculoskeletal

QEL-005 restores homeostasis in inflammatory disorders

Nov. 12, 2025
No Comments
Quell Therapeutics Ltd. have presented data for QEL-005, a new CAR Treg-based compound that targets CD19 and contains a FOXP3 phenotype lock.
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