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BioWorld - Tuesday, April 7, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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Handshake dollar sign

Novartis buying allergy firm Excellergy for $2B

March 27, 2026
By Karen Carey
No Comments
Just five months after raising a $70 million series A round, newly launched Excellergy Inc. agreed to a $2 billion M&A transaction that would bring its trifunctional allergic effector cell response inhibitors (ECRIs) to Novartis AG.
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Illustration of a road with three destination markers
Immune

Multibody TEV‘325 achieves preclinical milestone

March 26, 2026
No Comments
Biolojic Design Ltd. has earned an additional milestone payment from its collaboration partner, Teva Pharmaceutical Industries Ltd., for TEV‘325 (TEV-56308, formerly BD-9), a multibody targeting IL-13 and thymic stromal lymphopoietin (TSLP) for autoimmune disease
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Infection

Single-dose mRNA vaccine elicits superior anti-VZV immunity in mice

March 26, 2026
No Comments
Researchers from Chengdu Kanghua Biological Products Co. Ltd. recently published information on their novel varicella zoster virus (VZV) mRNA vaccine candidate (KH014). KH014 contains sequence-optimized mRNAs encoding full-length glycoprotein E encapsulated in ionizable lipid nanoparticles.
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Ha-Gyong-sik, CEO, Imbiologics

Imbiologics crosses $1B market cap with Kosdaq debut

March 24, 2026
By Marian (YoonJee) Chu
No Comments
Imbiologics Corp.’s market capitalization reached ₩1.5 trillion (US$1.02 billion) on its Kosdaq debut March 20, as the biotech seeks to become a leading antibody drugmaker for autoimmune diseases.
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Hands holding gears

Gilead pens dual-purpose $2B Ouro M&A deal with Galapagos

March 24, 2026
By Marian (YoonJee) Chu
No Comments
Gilead Sciences Inc. said after U.S. market close March 23 that it will acquire privately held Ouro Medicines LLC and its autoimmune BCMA/CD3 bispecific T-cell engager, gamgertamig, in a deal valued at $2.17 billion.
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Vials, syringes, and pills
BioEurope Spring

With improved technologies, biomarkers, failed drugs may come into their own

March 24, 2026
By Anette Breindl
No Comments
At BioEurope Spring 2026, pharma representatives and investors shared their thoughts about current and future landscapes of different disease areas, and on how to move toward success – both at the level of individual companies and for indications as a whole.
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Heart scientific overlay
Newco news

Immutrin raises £65M series A to take another run at reversing amyloidosis

March 24, 2026
By Nuala Moran
No Comments
Newco Immutrin Ltd. has raised £65 million (US$86.9 million) in a series A to take its lead antibody program through to clinical proof of concept in transthyretin amyloid cardiomyopathy.
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Gastrointestinal system with DNA, scientific background

Somatic genomics pioneer Quotient signs $2.2B IBD deal with Merck

March 24, 2026
By Karen Carey
No Comments
For a company founded only four years ago, Quotient Therapeutics Inc. entered its third major deal, this time with Merck & Co. Inc. to find novel drug targets for inflammatory bowel disease (IBD) using its somatic genomics platform technology.
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Immune

Milestone in CDR-Life and Boehringer Ingelheim partnership

March 24, 2026
No Comments
CDR-Life Inc. has announced the achievement of the first preclinical milestone under its 2025 license agreement with Boehringer Ingelheim Pharma GmbH & Co. KG. This milestone underscores progress in the companies’ efforts to develop next-generation antibody-based therapies for autoimmune diseases.
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Concept of business partnership

Kali signs $1.2B Sanofi deal for autoimmune asset KT-501

March 23, 2026
By Karen Carey
No Comments
T-cell engager company Kali Therapeutics Inc. licensed its lead product, CD19/BCMA/CD3 trispecific antibody KT-501, to Sanofi SA in a global deal that could be worth more than $1.2 billion. The San Mateo, Calif.-based biotech first emerged in 2024 and moved KT-501 into a phase Ia trial last week to treat adults with rheumatoid arthritis.
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