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BioWorld - Wednesday, August 10, 2022
Home » Topics » Disease categories and therapies » Immune

Immune
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Ke Xu, co-founder and CEO, Meta Pharma

Meta Pharma nets $15M in financing to develop its pipeline and AI drug platform

June 16, 2022
By Doris Yu
No Comments
Meta Pharmaceuticals Inc. has raised $15 million in seed and pre-series A rounds in six months for the pipeline and AI platform development. Shenzhen, China-based Meta Pharma plans to use the new funds to support its three candidates to enter clinical trials, as well as the development of its Meta-map platform for pipeline expansion.
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Peanut allergy illustration

With $194M financing and supportive phase III results in toddlers, DBV T plots comeback for peanut allergy patch

June 9, 2022
By Richard Staines
No Comments
In August 2020, it looked like DBV Technologies SA was in considerable trouble after the U.S. FDA served it with a rejection for its Viaskin Peanut allergy patch, raising concerns efficacy could be compromised because the product wasn’t sticking to the skin well. But could the Montrouge, France-based firm be making a comeback with the epicutaneous technology?
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Izokibep hits its marks in phase II psoriatic arthritis trial

June 7, 2022
By Cormac Sheridan
No Comments
Affibody AB and its development partners, Acelyrin Inc. and Inmagene Biopharmaceuticals Co. Ltd., are accelerating plans to move izokibep into phase III studies in psoriatic arthritis following better-than-expected phase II efficacy combined with an apparently clean safety profile.
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Izokibep hits its marks in phase II psoriatic arthritis trial

June 3, 2022
By Cormac Sheridan
No Comments
Affibody AB and its development partners, Acelyrin Inc. and Inmagene Biopharmaceuticals Co. Ltd., are accelerating plans to move the interleukin-17A inhibitor izokibep (formerly ABY-035) into phase III studies in psoriatic arthritis following better-than-expected phase II efficacy combined with an apparently clean safety profile.
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Immunic says its colitis failure won’t hamper MS program

June 2, 2022
By Lee Landenberger
No Comments
Poor phase II top-line data for Immunic Inc.’s lead candidate, vidofludimus calcium (IMU-838) hammered the stock June 2 as the study of the selective oral DHODH inhibitor missed its primary endpoint of clinical remission in treating moderate to severe ulcerative colitis. The failure means Immunic won’t pursue a phase III study on its own in the indication, but it won’t affect the company’s planned phase III studies of IMU-838 in treating relapsing multiple sclerosis (MS) and a phase II in treating progressive MS.
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Solomer-5-25.png

Not an antibody company: Elasmogen banks £8M to advance VNAR platform

May 25, 2022
By Nuala Moran
No Comments
Elasmogen Ltd. has secured a “transformational” £8 million (US$10 million) in new funding with which to move its shark-based, antibody-like constructs toward the clinic.
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Summer stock: Atara shares await July review of phase II MS trial

May 13, 2022
By Randy Osborne
No Comments
As the six-month interim analysis of phase II data for ATA-199 in progressive forms of multiple sclerosis (MS) nears, investors in Atara Biotherapeutics Inc. – not to mention patients – are growing more intrigued by the prospect, an off-the-shelf T-cell candidate that targets Epstein Barr virus-infected B cells and plasma cells in the central nervous system.
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Mooted reverse merger with Medsenic a lifeline for Bone Therapeutics

May 12, 2022
By Cormac Sheridan
No Comments
Bone Therapeutics SA has entered an exclusive three-month discussion period with Medsenic SAS, which could culminate in a reverse merger. The potential transaction represents a lifeline for the troubled Belgian cell therapy developer, which is running out of cash and which has been more or less abandoned by its shareholders.
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Pamela Conley, CEO, Nuvig
Newco news

‘Stable’ door opens for Nuvig as $47M series A backs homeostasis bid

May 11, 2022
By Randy Osborne
No Comments
Nuvig Therapeutics Inc. emerged from stealth mode with a $47 million series A round to back efforts to develop drugs that induce immune homeostasis as a way of treating autoimmune diseases without disturbing the system’s normal function.
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Hands holding gears

Amphista lands potentially rich deals with Merck, BMS

May 4, 2022
By Lee Landenberger
No Comments
Privately held Amphista Therapeutics Ltd. has cut massive deals with two biopharma giants, Merck KGaA and Bristol Myers Squibb Co. (BMS), that together could bring the company up to $2.25 billion. The companies will use Amphista’s Eclipsys platform to generate protein degrader-based therapeutics. Merck is looking to discover and develop small-molecule protein degraders for treating cancer and immune disease. Indications in the BMS deal were not announced.
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