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BioWorld - Monday, May 16, 2022
Home » Authors » Anette Breindl

Anette Breindl

Articles

ARTICLES

Assembling a draft Human Cell Atlas

Across body parts, ‘parts list’ gives insights into the lives of a cell

May 12, 2022
By Anette Breindl
No Comments
“People often think about the genome as the blueprint of the organism, but that’s not really correct,” Steven Quake told reporters at a Science press briefing earlier this week. “The genome is more of a parts list, because every cell type uses different parts.” Quake is president of the Chan Zuckerberg Biohub Network, and professor of bioengineering and applied physics at Stanford University.
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Back pain

Inflammation is key to preventing chronic pain, study finds

May 11, 2022
By Anette Breindl
No Comments
More than 10% of Americans suffer from chronic pain, and how to prevent acute pain from turning chronic has been a critical question in pain research. But according to a study published in the May 11, 2022, issue of Science Translational Medicine, that approach has it backwards. In several animal models of pain, the resolution of acute pain was an active process. Chronic pain happened when those active processes failed to occur.
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Breast cancer illustration
ESMO Breast Cancer 2022

Taking aim at tumor metabolism, while taming toxicity

May 10, 2022
By Anette Breindl
No Comments
There are 40 years of history behind the development of phosphoinositide 3-kinase (PI3K) inhibitors, Rebecca Dent told her audience at ESMO Breast Cancer 2022. And there have been success stories. There are five FDA-approved PI3K inhibitors in several cancer types, and in April, the FDA approved Vijoice (alpelisib; Novartis AG) for PIK3CA-related overgrowth spectrum, a rare disorder resulting from germline mutations of PIK3CA.
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Fallopian tubes, ovaries and uterus

Comparative study focuses lens of human reproductive aging

May 10, 2022
By Anette Breindl
No Comments
A comparison of seven nonhuman primate species has found both similarities and differences among the effects of age on female reproduction.
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Breast cancer illustration
ESMO Breast Cancer 2022

Taking aim at tumor metabolism, while taming toxicity

May 6, 2022
By Anette Breindl
No Comments
There are 40 years of history behind the development of phosphoinositide 3-kinase (PI3K) inhibitors, Rebecca Dent told her audience at ESMO Breast Cancer 2022. And there have been success stories. There are five FDA-approved PI3K inhibitors in several cancer types, and in April, the FDA approved Vijoice (alpelisib; Novartis AG) for PIK3CA-related overgrowth spectrum, a rare disorder resulting from germline mutations of PIK3CA.
Read More
Lymph nodes

In times of need, fat cells take on immune functions

May 4, 2022
By Anette Breindl
No Comments
Fat cells surrounding the lymph nodes could switch jobs in response to a distant infection, taking on immune cell functions, researchers at Johns Hopkins University reported in the May 3, 2022, online issue of Cell Metabolism.
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Inflammation illustration

Innate immune memory underlies inflammatory comorbidities: study

May 2, 2022
By Anette Breindl
No Comments
Researchers at the University of Pennsylvania have gained new insight into how different inflammatory conditions reinforce each other via trained innate immunity.
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Multiple sclerosis

Study finds targets of T-cell response in multiple sclerosis

April 28, 2022
By Anette Breindl
No Comments
Screening a panel of potential autoantigens, investigators at the Karolinska Institute have identified four autoantigens that are targeted by the T cells of multiple sclerosis patients.
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Antibiotic resistant bacteria inside a biofilm,

ECCMID 2022: In antibiotic development, scientific ingenuity meets a dysfunctional marketplace

April 26, 2022
By Anette Breindl
No Comments
Antibiotics drugs discovery, Ursula Theuretzbacher told the audience at the 2022 European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), has more than one challenge to overcome.
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Human anatomy

Sex disparities of lupus recapitulated in mouse model

April 25, 2022
By Anette Breindl
No Comments
A new animal model of systemic lupus erythematosus (lupus) could be useful for understanding the disparity of the disorder, which is vastly more common in women than men.
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View All Articles by Anette Breindl

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