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BioWorld - Tuesday, August 16, 2022
Home » Authors » Mar de Miguel

Mar de Miguel

Articles

ARTICLES

CAR T cell attacking cancer cells

New method developed to produce generic CAR T cells at scale

Aug. 12, 2022
By Mar de Miguel
No Comments
A new method has been devised to produce generic chimeric antigen receptor (CAR) T cells at scale by directing induced pluripotent stem cells to differentiate into mature T cells in vitro. The generic T cells can then be engineered to express a range of different chimeric antigen receptors.
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HIV infected cell

AIDS 2022: Scientists report progress in understanding how to eliminate latent HIV reservoirs

Aug. 10, 2022
By Mar de Miguel
No Comments
Researchers around the world are making advances in understanding how HIV becomes latent and seeking out vulnerabilities that could provide routes to targeting reservoirs and eliminating them.
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Pig organ cells

Whole body cellular function recovery in pigs after death

Aug. 4, 2022
By Mar de Miguel
No Comments
A new system for restoring cell function and tissues in mammals after death could expand the availability of organs for transplantation. The research also opens up a previously unexplored field of research in the molecular and cellular mechanisms triggered after death, an area of potential significance, since it covers different biological processes with multiple applications.
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Woman and 3D brain

Brain hypermutability is a process associated with aging

Aug. 1, 2022
By Mar de Miguel
No Comments
Sequence analysis of 131 human brains has revealed the mutagenesis processes that take place throughout life, from development to senescence. In a new study published in the July 29, 2022, issue of Science, the authors described how high rates of brain somatic mutations (what they call hypermutability) correlated with age.
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Person holding stomach in pain

Gut bug-produced histamine worsens abdominal pain in irritable bowel syndrome

July 29, 2022
By Mar de Miguel
No Comments
According to a new study published in the July 27, 2022, issue of Science Translational Medicine, a lower intake of fermentable carbohydrates produces changes in the intestinal microbiota that decrease histamine production reducing chronic abdominal pain in patients with irritable bowel syndrome.
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Antibodies attacking cancer cell

Monoclonal antibody pairs "zipper" to target cancer

July 27, 2022
By Mar de Miguel
No Comments
Two targets, double success. This is the logic behind a new approach that uses monoclonal antibody pairs to fight cancer.
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Novel coronavirus SARS-CoV-2

SARS-CoV-2 infection of neurons; no ACE2 required

July 22, 2022
By Mar de Miguel
No Comments
Since the isolation of SARS-CoV-2 and the study of its infection mechanisms, scientists have been trying to understand how this virus accesses the brain and produces neurological symptoms. The receptor necessary for the virus to enter the cell by endocytosis (the receptor for angiotensin-converting enzyme 2, ACE2) is only expressed by some neurons and is hardly detected in the brain.
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Cancer cells

Oncogenic collagen allows cancer cells to evade immune response

July 22, 2022
By Mar de Miguel
No Comments
Cancer cells may evade the immune response thanks to a special type of collagen, scientists reported in a new study published in the July 21, 2022, issue of Cancer Cell. Researchers at The University of Texas MD Anderson Cancer Center have discovered oncogenic collagen secreted by cancer cells that differs from normal collagen.
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Novel coronavirus SARS-CoV-2

SARS-CoV-2 infection of neurons; no ACE2 required

July 21, 2022
By Mar de Miguel
No Comments
Since the isolation of SARS-CoV-2 and the study of its infection mechanisms, scientists have been trying to understand how this virus accesses the brain and produces neurological symptoms.
Read More
Lung illustration

Mutation-specific targeting increases transporter protein in cystic fibrosis

July 20, 2022
By Mar de Miguel
No Comments
A study published in Nature Communications revealed a new antisense oligonucleotide therapy applicable to the W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene in cystic fibrosis.
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View All Articles by Mar de Miguel

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