Science

BioWorld MedTech’s Orthopedics Extra for Feb. 19, 2020

February 19, 2020

Keeping you up to date on recent developments in orthopedics, including: In2bones reports U.S. Launch of the Avenger radial head prosthesis; Searching for biomarkers and therapeutic agents against breast cancer; MRI findings predict shoulder stiffness for rotator cuff tears.

The lysosome link

Strengthening lysosomes could head Parkinson’s off at the pass

February 19, 2020

By Anette Breindl

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Parkinson’s disease (PD) is a neurodegenerative disorder. But not just. And it may not start that way. There is increasing evidence that a-synuclein, the protein whose aggregates eventually destroy midbrain dopaminergic neurons in PD (and that are the cause of other diseases collectively known as the synucleinopathies), first aggregates “in enteric neurons, the neurons that control gastrointestinal function,” Collin Challis told BioWorld.

AAAS 2020: Progress in Human Cell Atlas unveiling underlying mechanisms of disease

February 19, 2020

By Nuala Moran

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SEATTLE – As it enters its third year, the Human Cell Atlas project has mapped 100 million of 100 billion cells, and by comparing gene expression profiles of normal and aberrant cells and building networks of cellular interactions, is leading to breakthroughs in understanding of disease at a molecular level.

American Association for the Advancement of Science

Researchers trace COVID-19’s family tree to battle outbreak and ‘infodemic’

February 18, 2020

By Nuala Moran

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SEATTLE – Tracing the family tree of COVID-19 through its evolving DNA sequence makes it possible to disprove many false claims circulating on social media about the novel coronavirus, and, in particular, that it was generated in a covert biological weapons program. “From everything I’ve looked at, there is zero evidence for genetic engineering; it looks like normal evolution,” said Trevor Bedford, a computational biologist at Fred Hutchinson Cancer Research Center, who has been using genomes sequences taken from patient samples to track the spread of the virus since Jan. 11.

BioWorld MedTech’s Oncology Extra for Feb. 18, 2020

February 18, 2020

By Mark McCarty and Anette Breindl

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Keeping you up to date on recent developments in oncology, including: New approach to photothermal treatment beats biofilm problem; Origin story helps ovarian cancer prognosis; Sharper look yields new potential kinase target in ovarian cancer; Autophagy activation may prevent metastasis.

AAAS 2020: Progress in Human Cell Atlas unveiling underlying mechanisms of disease

February 18, 2020

By Nuala Moran

No Comments

SEATTLE – As it enters its third year, the Human Cell Atlas project has mapped 100 million of 100 billion cells, and by comparing gene expression profiles of normal and aberrant cells and building networks of cellular interactions, is leading to breakthroughs in understanding of disease at a molecular level.

American Association for the Advancement of Science

Researchers trace COVID-19’s family tree to battle outbreak and ‘infodemic’

February 18, 2020

By Nuala Moran

No Comments

SEATTLE – Tracing the family tree of COVID-19 through its evolving DNA sequence makes it possible to disprove many false claims circulating on social media about the novel coronavirus, and, in particular, that it was generated in a covert biological weapons program.

American Association for the Advancement of Science

Researchers trace COVID-19’s family tree to battle outbreak and ‘infodemic’

February 14, 2020

By Nuala Moran

No Comments

SEATTLE – Tracing the family tree of COVID-19 through its evolving DNA sequence makes it possible to disprove many false claims circulating on social media about the novel coronavirus, and, in particular, that it was generated in a covert biological weapons program. “From everything I’ve looked at, there is zero evidence for genetic engineering; it looks like normal evolution,” said Trevor Bedford, a computational biologist at Fred Hutchinson Cancer Research Center, who has been using genomes sequences taken from patient samples to track the spread of the virus since Jan. 11.

BioWorld MedTech’s Neurology Extra for Feb. 14, 2020

February 14, 2020

By Andrea Applegate

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Keeping you up to date on recent developments in neurology, including: PTSD linked to a dysfunction of the brain networks that control memory; Molecule offers hope for halting Parkinson's; Brain abnormalities associated with schizophrenia in individuals with 22q revealed.

Bench Press for Feb. 14, 2020

February 14, 2020

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BioWorld looks at translational medicine, including: Ebola survivor's antibodies reveal therapeutic targets; JAK inhibitors build bone, no inflammation necessary; Origin story helps ovarian cancer prognosis; Celiac model captures gluten, genetics and gut reactions; New search method, new antibiotic MOA; Nanogold improves MS symptoms; Autophagy helps repair lung injury; How hook(worm)s grapple with nets; Thanks for the memories, myelin; Heat-shock proteins’ subtler cousin.