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BioWorld - Wednesday, December 10, 2025
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Neurology/psychiatric

Technique for aging brain organoids makes better Alzheimer’s model

Aug. 21, 2025
By Nuala Moran
No Comments
A new method for accelerating the maturation of neuronal cell models and brain organoids is poised to make it possible to track the etiology of neurodegenerative diseases that develop over decades. The non-invasive technique uses graphene to convert light into electrical cues that prompt neurons to connect and communicate in vitro.
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Technique for aging brain organoids makes better Alzheimer’s model

Aug. 20, 2025
By Nuala Moran
No Comments
A new method for accelerating the maturation of neuronal cell models and brain organoids is poised to make it possible to track the etiology of neurodegenerative diseases that develop over decades.
Read More
Hands holding pink paper kidneys
Nephrology

New research solves mystery of sex differences in acute kidney injury

Aug. 18, 2025
By Nuala Moran
No Comments
German researchers have cracked the decades-long mystery of why males are more susceptible to acute kidney injury than females, demonstrating that estrogen has a protective effect in females.
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Medical illustration showing the front view of the brain in the skull.

Meninges’ lymphoid structures, not so good, so bad, or so ugly

Aug. 15, 2025
By Mar de Miguel
No Comments
A little-known tissue composed of a cluster of immune cells could offer novel insights into the development of neurological disorders. Meninges' immune system changes with age and neurodegeneration. Are they protecting the brain or fueling disease?
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Hands holding pink paper kidneys

New research solves mystery of sex differences in acute kidney injury

Aug. 15, 2025
By Nuala Moran
No Comments
German researchers have cracked the decades-long mystery of why males are more susceptible to acute kidney injury than females, demonstrating that estrogen has a protective effect in females.
Read More
Hands holding pink paper kidneys

New research solves mystery of sex differences in acute kidney injury

Aug. 14, 2025
By Nuala Moran
No Comments
German researchers have cracked the decades-long mystery of why males are more susceptible to acute kidney injury than females, demonstrating that estrogen has a protective effect in females.
Read More
Illustration of women's reproductive organs
Women's health

UK MHRA highlights potential of the vaginal microbiome in women’s health

Aug. 13, 2025
By Nuala Moran
No Comments
The U.K. Medicines and Healthcare products Agency (MHRA) is calling for more research into the vaginal microbiome as a way to redress the historic under-representation of women in clinical studies, which it said has contributed to “critical shortcomings” in understanding of female-specific conditions.
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Illustration of women's reproductive organs

UK MHRA highlights potential of the vaginal microbiome in women’s health

Aug. 12, 2025
By Nuala Moran
No Comments
The U.K. Medicines and Healthcare products Agency (MHRA) is calling for more research into the vaginal microbiome as a way to redress the historic under-representation of women in clinical studies, which it said has contributed to “critical shortcomings” in understanding of female-specific conditions.
Read More
Illustration of DNA methylation by the DNA methyl transferase I

NSD2 inhibitors close chromatin and silence aggressive oncogenes

Aug. 12, 2025
By Mar de Miguel
No Comments
Experimental drugs that directly inhibit the NSD2 enzyme have shown potential as an effective strategy against hard-to-treat cancers, such as lung and pancreatic tumors driven by KRAS mutations. The therapeutic mechanism involves reversing a histone H3 methylation that promotes open chromatin and the expression of oncogenes.
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Genome sequence map
Immune

UK’s DecodeME uncovers genetic link for chronic fatigue

Aug. 12, 2025
By Nuala Moran
No Comments
The largest genome-wide association study to date of myalgic encephalomyelitis/chronic fatigue syndrome has identified eight genetic loci that are significantly associated with the chronic debilitating condition. Onset of ME/CFS often is traced back to an infection and four of the loci involve genes that are expressed in response to viral or bacterial infections.
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