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BioWorld - Friday, July 18, 2025
Home » Authors » Coia Dulsat

Coia Dulsat

Articles

ARTICLES

Illustration of dividing breast cancer cell
Cancer

Chemotherapy-induced neutrophil traps ignite lung relapse

July 9, 2025
By Coia Dulsat
No Comments
Researchers at the Chinese Academy of Sciences and collaborators have developed a new method to label and monitor dormant breast cancer cells over time, shedding light on how these cells survive chemotherapy and potentially trigger metastatic relapse in the lung. Breast cancer frequently recurs in distant metastatic sites, even after the primary tumor has fully regressed following initial therapy.
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Dendritic cells
Cancer

EACR 2025: A look into next-generation strategies in cancer

June 20, 2025
By Coia Dulsat
No Comments
At the Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, multiple sessions aimed to provide fresh perspectives on the always challenging treatment of cancer, with a strong focus on innovative strategies.
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3D representation of tumor microenvironment
Cancer

EACR 2025: Immune rewiring in cancer orchestrates tumor microenvironment

June 18, 2025
By Coia Dulsat
No Comments
Among the presentations included in the Top Abstracts category at the recently inaugurated Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, it is worth highlighting two that respectively addressed the role of cytokines and lipid-sensing receptors as key modulators of the tumor microenvironment, a central theme in current cancer research.
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X/Y chromosomes

Loss of Y chromosome in cancer, immune cells: a new clue to cancer outcomes

June 6, 2025
By Coia Dulsat
No Comments
Researchers from the University of Arizona have unveiled that coordinated Y chromosome loss in both cancer cells and immune cells may explain the worse prognosis in people with this alteration. The loss of the Y chromosome (LOY) is one of the most frequent somatic mutations in men, particularly with advancing age. Investigating the mechanisms and effects of LOY in peripheral blood mononuclear cells and its association with immune and tumor cells, they “found a relationship between the Y chromosome loss in normal cells inside the tumor and the Y chromosome loss inside the cancer cell,” Dan Theodorescu, senior author of the study, told BioWorld.
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X/Y chromosomes
Cancer

Loss of Y chromosome in cancer, immune cells: a new clue to cancer outcomes

June 5, 2025
By Coia Dulsat
No Comments
Researchers from the University of Arizona have unveiled that coordinated Y chromosome loss in both cancer cells and immune cells may explain the worse prognosis in people with this alteration. The loss of the Y chromosome is one of the most frequent somatic mutations in men, particularly with advancing age.
Read More
X/Y chromosomes
Cancer

Loss of Y chromosome in cancer, immune cells: a new clue to cancer outcomes

June 5, 2025
By Coia Dulsat
No Comments
Researchers from the University of Arizona have unveiled that coordinated Y chromosome loss in both cancer cells and immune cells may explain the worse prognosis in people with this alteration. The loss of the Y chromosome (LOY) is one of the most frequent somatic mutations in men, particularly with advancing age. Investigating the mechanisms and effects of LOY in PBMCs and its association with immune and tumor cells, they “found a relationship between the Y chromosome loss in normal cells inside the tumor and the Y chromosome loss inside the cancer cell,” Dan Theodorescu, senior author of the study, told BioWorld.
Read More
3D illustration of T cells fighting cancer
Cancer

Modified viral protein boosts T cell power via STAT5

May 27, 2025
By Coia Dulsat
No Comments
Researchers at the University of Michigan designed an optimized viral protein able to boost the antitumor function of T cells. The project stemmed from observations on the particular system employed by Herpesvirus saimiri to infect T cells and hijack cellular pathways by activating them.
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Woman receiving radiotherapy treatments for cancer
Cancer

Amphiregulin drives metastasis through a paradoxical ‘badscopal’ effect of radiotherapy

May 20, 2025
By Coia Dulsat
No Comments
Researchers at the University of Chicago have shed light on the role of tumor-promoting factors induced by radiotherapy and their potential impact on future therapeutic strategies. The article, published in Nature on May 14, 2025, points to radiation-induced amphiregulin as a key driver of tumor metastasis.
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3d illustration of ovarian cancer
Cancer

Lipid uptake drives immune evasion in high-grade serous ovarian cancer

May 13, 2025
By Coia Dulsat
No Comments
Researchers from Trinity College Dublin, Princeton University and collaborators have discovered that blocking the uptake of lipids by immune cells within the ascites microenvironment could reshape treatment for advanced ovarian cancer.
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Silhouette of head, brain

ADPD 2025: Novel treatment modalities in neurodegenerative disorders

April 10, 2025
By Coia Dulsat
The current treatment strategies for neurodegenerative diseases focus on targeting Aβ in Alzheimer’s disease (AD), α-synuclein aggregates in Parkinson’s disease (PD) and anti-tau therapies, which are primarily used in AD but are also being explored for PD. At the 2025 International Conference of Alzheimer’s & Parkinson’s Disease and Related Neurological Disorders, Aditya Iyer, senior RD scientist from Amyl Therapeutics Srl, presented data on an option which could potentially serve as a pan-amyloid therapeutic.
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View All Articles by Coia Dulsat

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