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BioWorld - Tuesday, July 28, 2026
Home » Topics » Clinical

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China compass

ASCO 2026: Chinese biopharma arrives at ASCO with pivotal wins

June 5, 2026
By Tamra Sami
No Comments
If the 2026 American Society of Clinical Oncology (ASCO) annual meeting in Chicago from May 30 to June 3 demonstrated anything about the evolution of China’s biotechnology sector, it was that the industry’s center of gravity is shifting. While Chinese companies once relied heavily on PD-1 antibodies and licensing deals to gain international visibility, this year’s oral presentations showcased a broader innovation base.
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Swab sample and patient

Roche develops PCR test to detect the Ebola Bundibugyo virus

June 5, 2026
By Shani Alexander
No Comments
Roche Holding AG has rapidly developed a research-use only molecular PCR test to detect the rare Ebola Bundibugyo virus, to support response efforts amid the ongoing outbreak in the Democratic Republic of Congo and Uganda. The test comes as commentary in The Lancet this week underscored the urgent need for a fit-for-purpose diagnostic test, as it warned that the absence of reliable testing is hampering efforts to ascertain the scale of the epidemic and understand the transmissibility of this strain of Bundibugyo virus.
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3D dollar sign

Ona raises $86.6M series B for ADCs to treat advanced cancers

June 4, 2026
By Nuala Moran
No Comments
Antibody-drug conjugate (ADC) specialist Ona Therapeutics SL has closed an oversubscribed series B at $86.6 million, as clinical development of the lead program ONA-255 in advanced treatment-resistant breast cancer gathers steam.
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Woman taking medication for mental illness

Autobahn on the fast track with bipolar thyroid agonist

June 4, 2026
By Karen Carey
No Comments
Achieving high marks in the phase II Amplify-BD trial for bipolar I and II depression, Autobahn Therapeutics Inc.’s elunetirom, a brain-penetrant central nervous system thyroid hormone receptor agonist, or thyromimetic, is moving toward a registrational path and a clinical readout in major depressive disorder.
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Gastric cancer

Innovent submits NDA for CLDN18.2 ADC for gastric cancer

June 4, 2026
By Tamra Sami
No Comments
Innovent Biologics Co. Ltd.’s Claudin18.2-targeted antibody-drug conjugate (ADC), arcotatug tavatecan (IBI-343, TAK-921), met the primary endpoint in the international multicenter phase III G-Hope-001 trial in advanced gastric cancer, according to interim results.
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Diffuse large B-cell lymphoma - isometric view

Zynlonta Lotis position in DLBCL strains ADC shares

June 4, 2026
By Randy Osborne
No Comments
ADC Therapeutics SA blamed patients’ advanced age on the death imbalance in the phase III Lotis-5 confirmatory trial testing Zynlonta (loncastuximab tesirine-lpyl) in combination with rituximab to treat relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL). Whatever the reason, Wall Street wasn’t pleased and shares (NYSE:ADCT) closed June 4 at $1.32, down 57%, or $1.77.
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Art concept for liver damage, such as fatty liver, fibrosis or cirrhosis

D&D’s zabopegdutide shows more upbeat top-line phase II MASH data

June 2, 2026
By Marian (YoonJee) Chu
No Comments
D&D Pharmatech Inc. announced May 27 positive top-line tissue biopsy results of zabopegdutide (DD-01) from a 48-week phase II study of metabolic dysfunction-associated steatohepatitis (MASH), pushing company shares up 30% on the day.
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Person holding stomach in pain

Cancer specter looming, Abtect effect in UC wallops Abivax

June 2, 2026
By Randy Osborne
No Comments
Although analysts liked the data – calling them “truly amazing” and “transformational” – Wall Street apparently had qualms about three cancer cases that turned up in phase III top-line data from the Abtect maintenance trial with obefazimod. Paris-based Abivax SA’s oral, first-in-class miRNA-124 enhancer performed well in adults with moderately to severely active ulcerative colitis (UC), but shares of (NASDAQ:ABVX) closed June 2 at $72.50, down 44%, or $57.19.
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Grail Galleri multicancer early detection test

ASCO 2026: Grail shifts focus to secondary endpoints in UK study

June 1, 2026
By Nuala Moran
No Comments
New data from Grail Inc.’s randomized study of its Galleri multicancer early detection test could not alter the fact that the U.K. trial missed the primary endpoint of reducing the number of cancers diagnosed at stage III and stage IV. But the company is now suggesting that discounting the initial screen, when most late stage cancers were detected, would be more representative of a real-life steady state screening program.
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Hand holding elbow

Phase II bid Turns out safe, EASI, effective; AD topical island?

June 1, 2026
By Randy Osborne
No Comments
Turn Therapeutics Inc. made public strongly positive findings from an interim analysis that involves the first 50 subjects in the ongoing phase II atopic dermatitis (AD) trial with IL-36 inhibitor GX-03.
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