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BioWorld - Wednesday, July 6, 2022
Home » Topics » Respiratory, BioWorld Asia

Respiratory, BioWorld Asia
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Insilico raises $60M to invest in AI platform and IPF program

June 14, 2022
By Doris Yu
No Comments
AI-enabled drug discovery company Insilico Medicine Ltd. has raised $60 million in a series D round to support expansion of its pipeline.
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Lungs

Bridge Biotherapeutics inks ₩30B deal with Shaperon for GPCR19 agonist

April 26, 2022
By Gina Lee
No Comments
Bridge Biotherapeutics Inc. inked an exclusive in-license agreement for Shaperon Inc.’s G protein-coupled receptor 19 (GPCR19) agonist, BBT-209, a potential treatment for idiopathic pulmonary fibrosis. Bridge will pay Shaperon ₩2 billion (US$1.63 million) up front. The potential deal value, which includes up-front, milestone, and royalty payments, is ₩30 billion.
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James Jungkue Lee, CEO, Bridge Biotherapeutics

Bridge Biotherapeutics secures second IPF candidate, targets IND by late 2022

March 15, 2022
By Gina Lee
No Comments

Bridge Biotherapeutics Inc. has signed an exclusive option-to-license agreement for Cellionbiomed Inc.’s preclinical ion channel modulator, BBT-301, thus adding a second idiopathic pulmonary fibrosis (IPF) candidate to its fibrotic diseases portfolio. The company hopes to enter the clinic with the drug in the U.S. by the end of 2022.


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Mesoblast shares depressed by Novartis deal termination

Dec. 21, 2021
By Tamra Sami
No Comments
PERTH, Australia – It’s been a year that Mesoblast Ltd. might like to forget. The company’s stock dropped 17% Dec. 15 on the news that Novartis AG will terminate its licensing agreement with Mesoblast for remestemcel-L.
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Lung illustration

Splisense raises $28.5 million in series B to advance cystic fibrosis therapy

May 18, 2021
By David Ho
No Comments
HONG KONG – Splisense Ltd. has closed a $28.5 million series B financing that it said will support pipeline development including its lead antisense oligonucleotide candidate, SPL84-23, for the potential treatment of cystic fibrosis. The Jerusalem-based company, which develops mRNA-altering therapies for CF and other genetic pulmonary diseases, attracted support for the round from Orbimed, Israel Biotech Fund, Biotel Ltd. and the Cystic Fibrosis Foundation.
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Coronavirus, lungs, hand holding stethoscope

Mesenchymal semifinals: ARDS hard but could Mesoblast’s Ryoncil still thrill in GVHD?

Dec. 22, 2020
By Randy Osborne
No Comments
An evolving COVID-19 treatment paradigm may have foiled Mesoblast Ltd.’s phase III with remestemcel-L in ventilator-dependent patients with moderate to severe acute respiratory distress syndrome (ARDS), CEO Silviu Itescu said, but hope remains in pediatric steroid-refractory acute graft-vs.-host disease (GVHD).
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Lungs

Taiho acquires Japan rights for LTI-01, Lung Tx’s therapeutic for LPE

Nov. 24, 2020
By Gina Lee
No Comments
HONG KONG – Taiho Pharmaceutical Co. Ltd. has signed an exclusive license agreement with Lung Therapeutics Inc., picking up the Japanese rights to Lung Tx’s LTI-01.
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Respiratory infection

Mesoblast licenses remestemcel-L to Novartis in deal worth up to $1.3B

Nov. 24, 2020
By Tamra Sami
No Comments
PERTH, Australia – Mesoblast Ltd. inked an exclusive global licensing deal with Novartis AG for the development, manufacture and commercialization of Mesoblast’s mesenchymal stromal cell product remestemcel-L, with an initial focus on the acute respiratory distress syndrome, including that associated with COVID-19, just six weeks after the FDA issued a complete response letter for the therapy as a treatment for steroid-refractory acute graft-versus-host disease.
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Lungs wireframe illustration

FDA approves Pharmaxis’ Bronchitol for cystic fibrosis as company looks to myelofibrosis

Nov. 3, 2020
By Tamra Sami
No Comments
PERTH, Australia – With the approval of cystic fibrosis treatment Bronchitol (mannitol), Sydney-based Pharmaxis Ltd. joins a small group of elite Australian biotech companies to take their drugs all the way to FDA approval.
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Lungs

Dimerix’s lead candidate to enter global REMAP-CAP trial to treat COVID-19 ARDS

June 9, 2020
By Tamra Sami
No Comments
PERTH, Australia – Melbourne, Australia-based Dimerix Ltd. saw its shares gain 66% on the news that its lead candidate, DMX-200, has been chosen to enter the global REMAP-CAP platform trial as a potential treatment  for COVID-19-related acute respiratory distress syndrome (ARDS).
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