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Home » Newsletters » BioWorld

BioWorld

Feb. 10, 2025

View Archived Issues
Female scientist looking through microscope

Scientists warn NIH cost-cutting will impair research

From Feb. 10, the U.S. NIH is to cut the amount of its grants that go to indirect costs, in a move it says will save $4 billion per annum, but which scientists say will hit breakthrough biomedical research. The NIH announced the cut on Friday, Feb. 7, saying there would be a flat rate of 15% for indirect costs, such as running laboratories, buying and maintaining equipment, data processing and storage, across all of its grants. That compares to an average rate historically of between 27% and 28%, the NIH said. Read More

BIO CEO 2025: A ‘nice upswing’ in VC rounds, but uncertainty looms

Raising money to advance promising science is a constant struggle, bringing biopharma executive leadership together to learn about investment strategies in the opening session at the Biotechnology Innovation Organization’s CEO and Investor Conference in New York. “We’re bottoms-up investors. If we like the technology, we like the product, we think it’s going to work, we want to find a way to invest,” said Chris Garabedian, chairman and CEO of Xontogeny. Read More
Liver illustration

Olix wins $630M deal from Eli Lilly for phase I MASH asset

Olix Pharmaceuticals Inc. walked the talk in realizing a new $630 million licensing deal with Eli Lilly and Co. for its cardiovascular and metabolic disease asset, OLX-702A (OLX-75016), rallying stock by 30% after it had largely recovered from a terminated deal with France’s Théa Open Innovation last year. Read More

Pliant shares bend under IPF bexotegrast phase IIb pause

A mysterious turn in the phase IIb story with idiopathic pulmonary fibrosis (IPF) candidate bexotegrast sent shares of Pliant Therapeutics Inc. (NASDAQ:PLRX) down 60.6%, or $4.72, to close Feb. 10 at $3.07. Read More
Eya and DNA illustration

4D’s new data in wet AMD bolster its phase III study vision

4D Molecular Therapeutics Inc.’s gene therapy, 4D-150, in wet age-related macular degeneration (wet AMD) produced positive phase IIb data as the company preps two phase III studies set to begin this year. Read More

Efforts revived to stem flow of US funding for China R&D

The Biosecure Act may have died with the 118th U.S. Congress, but efforts to stop U.S. government funding of R&D in China are alive and well. Rep. Claudia Tenney, R-N.Y., introduced the Stop Funding our Adversaries Act in the House Feb. 7 to prohibit direct and indirect federal funding of research in China or entities owned by China. Read More

Critics of Super Bowl Rx ad call for new playbook

Amid a strengthening offensive against direct-to-consumer drug ads, two senators flagged a Super Bowl ad promoting compounded drugs as part of the company’s attack on the U.S. weight-loss industry that it said was built to keep Americans “sick and stuck.” Read More

ICYMI: Week in review, Feb. 3-7, 2025

A quick look back at top stories. Read More

Biggest gainers and losers for Feb. 3-7, 2025

The top 10 biopharma stock gainers and losers for the week. Read More
BW-PFA-report-5Feb

New report offers insight on pulsed field ablation

With the first company in the world announcing more than $1 billion in annual revenue from pulsed field ablation on Feb. 5, Clarivate plc and BioWorld MedTech’s latest report provides well-timed insight into the stunning growth and bright future of this new medical technology for the treatment of atrial fibrillation. Read More

Appointments and advancements for Feb. 10, 2025

New hires and promotions in the biopharma industry, including: Cosette, Entero, Imunon, Santhera. Read More

Financings for Feb. 10, 2025

Biopharmas raising money in public or private financings, including: Aardvark, Ascentage, Jyong, Neuronetics, Palatin. Read More

In the clinic for Feb. 10, 2025

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Cyclo, Denali, Eli Lilly, Genentech, Novo Nordisk, Replicate, Roche. Read More

Other news to note for Feb. 10, 2025

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Genentech, Intermune, Legacy Pharma, Roche. Read More

Regulatory actions for Feb. 10, 2025

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Bio-Thera. Read More

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