Deal title

Principal
company

Partner
company

Total projected at signing (US$M)

Start date

May

Mundipharma to distribute Endoceutics' prasterone in Middle East and Africa

Endoceutics Inc.

Mundipharma International Corp. Ltd.

Payment unspecified

5/20/18

Adaptive and Sanofi to assess minimal residual disease status in response to isatuximab for multiple myeloma using Clonoseq assay

Adaptive Biotechnologies Corp.

Sanofi SA

Payment unspecified

5/29/18

Arix and Evotec to establish a joint venture for cancer and infectious disease drug development

Arix Bioscience plc

Evotec AG

Payment unspecified

5/31/18

Novartis to develop BDD's Oralogik technology for an undisclosed compound

BDD Pharma Ltd.

Novartis Pharma AG

Payment unspecified

5/30/18

Centogene to support Orphazyme's arimoclomol clinical trials for treatment of neuronopathic Gaucher disease in India

Centogene Gmbh

Orphazyme Aps

Payment unspecified

5/23/18

Sun Pharma to commercialize Churchill Pharma's Yonsa for prostate cancer

Churchill Pharmaceuticals LLC

Sun Pharmaceutical Industries Ltd.

Payment unspecified

5/23/18

Clinigen Group to initiate Managed Access Program for MTPC's edaravone in Europe

Clinigen Group plc

Mitsubishi Tanabe Pharma Corp.

Payment unspecified

5/22/18

Clinigen to provide supply and distribution services for Nordic's aprotinin to prevent blood loss in Asia Pacific and South Africa

Clinigen Group plc

Nordic Pharma

Payment unspecified

5/24/18

Clinigen to commercialize Bristol Myers Squibb's products in South Africa

Clinigen Group plc

Bristol-Myers Squibb Co.

Payment unspecified

5/31/18

Cloud Pharmaceuticals to design novel small-molecule agents to GSK specified targets

Cloud Pharmaceuticals Inc.

Glaxosmithkline plc

Payment unspecified

5/30/18

Zai Lab to develop and commercialize Crescendo Biologics' antibody VH domain therapeutic against inflammatory disease worldwide

Crescendo Biologics Ltd.

Zai Lab Ltd.

Payment unspecified

5/30/18

Darman Ara to distribute MDI's products including Penthrox for pain relief in Iran

Darman Ara Co.

Medical Developments International Ltd.

Payment unspecified

5/29/18

Glenmark to manufacture and supply Elite's two generic products

Elite Pharmaceuticals Inc.

Glenmark Pharmaceuticals Ltd.

Payment unspecified

5/22/18

Novo Nordisk to develop and commercialize Epigen's EPGN-696 against diabetic and chronic kidney diseases worldwide

Epigen Biosciences Inc.

Novo Nordisk A/S

$200.00

5/23/18

FM and Merck to develop pan-cancer companion diagnostic tests for Keytruda

Foundation Medicine Inc.

Merck & Co. Inc.

Payment unspecified

5/24/18

Molmed and Glycostem to enter a binding term sheet to develop and manufacture new natural killer cells-based allogeneic chimeric antigen receptor therapies for cancer

Glycostem BV

Molmed SpA

Payment unspecified

5/31/18

H. Lundbeck divesting two research programs to Mindimmune Therapeutics

H. Lundbeck A/S

Mindimmune Therapeutics Inc.

Payment unspecified

5/22/18

Abcellera and Harbour Antibodies to combine single-cell antibody discovery capabilities and H2L2 transgenic mouse platform for the discovery of antibodies

Harbour Antibodies BV

Abcellera Biologics Inc.

Payment unspecified

5/30/18

Celsius Therapeutics to use Harbour Biomed's H2L2 fully human antibody discovery platform to discover fully human monoclonal antibodies

Harbour Biomed

Celsius Therapeutics Inc.

Payment unspecified

5/31/18

Hitgen to discover compounds for Forma Therapeutics' targets using DNA-encoded libraries worldwide

Hitgen Ltd.

Forma Therapeutics Inc.

Payment unspecified

5/31/18

Shionogi to develop, manufacture and commercialize Hsiri's therapeutics for nontuberculous mycobacteria diseases and tuberculosis worldwide

Hsiri Therapeutics LLC

Shionogi & Co. Ltd.

Payment unspecified

5/31/18

IMV and PCI Biotech to evaluate the formulation compatibility of respective technologies in the field of nucleic acid therapeutics

IMV Inc.

PCI Biotech Holding ASA

Payment unspecified

5/24/18

Pivot to acquire option to use Ip Med's Trivair for the delivery of ready to infuse cannabis products worldwide

Ip Med Inc.

Pivot Pharmaceuticals Inc.

Payment unspecified

5/31/18

Antengene to develop and commercialize Karyopharm's selinexor, eltanexor, KPT-9274 for oncology and verdinexor for non-oncology in China and other regions in Asia

Karyopharm Therapeutics Inc.

Antengene Corp.

$162.00

5/23/18

Virpax to use Medpharm's Medspray technology to deliver DSF-100 for pain

Medpharm Ltd.

Virpax Pharmaceuticals Inc.

Payment unspecified

5/29/18

Mesoblast and Cartherics to develop allogeneic chimeric antigen receptor T cell-based immunotherapies for solid cancers

Mesoblast Ltd.

Cartherics Pty Ltd.

Payment unspecified

5/29/18

Mitsubishi Chemical, Ono and Daiichi to launch a consortium to discover drugs for intractable immune-mediated inflammatory diseases

Mitsubishi Chemical Holdings Corp.

Ono Pharmaceutical Co. Ltd.

Payment unspecified

5/30/18

Syndax and Nektar to evaluate the combination of NKTR-214 and entinostat for metastatic melanoma

Nektar Therapeutics

Syndax Pharmaceuticals Inc.

Payment unspecified

5/30/18

Oncodna to provide patient enrollment services to Kura Oncology's tipifarnib trial in patients with head and neck squamous cell carcinoma

Oncodna SA

Kura Oncology Inc.

Payment unspecified

5/22/18

Tanner to distribute Partner's Leukine for bone marrow transplantation worldwide, excluding the U.S. and Canada

Partner Therapeutics Inc.

Tanner Pharma Group plc

Payment unspecified

5/24/18

Acerus to commercialize Pharmanest's Shact for pain in Canada

Pharmanest AB

Acerus Pharmaceuticals Corp.

Payment unspecified

5/31/18

Emergent to develop Profectus' Nipah virus vaccine

Profectus Biosciences Inc.

Emergent Biosolutions Inc.

Payment unspecified

5/24/18

Replimune and Regeneron to evaluate RP-1 in combination with cemiplimab against cutaneous squamous-cell carcinoma

Replimune Group Inc.

Regeneron Pharmaceuticals Inc.

Payment unspecified

5/29/18

Rigel to distribute Biologics' Tavalisse for thrombocytopenia

Rigel Pharmaceuticals Inc.

Biologics Inc.

Payment unspecified

5/29/18

Five Prime and Roche to develop immunohistochemistry companion diagnostic assays for use with bemarituzumab and FPA-150 for cancer

Roche Holding AG

Five Prime Therapeutics Inc.

Payment unspecified

5/30/18

Los Altos to develop and commercialize Sedor's CE-Meloxicam for pain in China, Taiwan, Hong Kong and Macau

Sedor Pharmaceuticals LLC

Los Altos Pharmaceuticals Inc.

Payment unspecified

5/30/18

Seed Health to commercialize Optibiotix's LP-LDL products for cholesterol and blood pressure in the U.S.

Seed Health Inc.

Optibiotix Health plc

Payment unspecified

5/22/18

Shuwen to develop companion diagnostics for Bliss' cancer drugs

Shuwen Biotech Co. Ltd.

Bliss Biopharmaceutical Co. Ltd.

Payment unspecified

5/28/18

Oncolys Biopharma to license intellectual property related to Therm-SB from Stabilitech worldwide

Stabilitech Ltd.

Oncolys Biopharma Inc.

Payment unspecified

5/23/18

Aska to develop and commercialize Takeda's relugolix for uterine fibroids and endometriosis in Japan

Takeda Pharmaceutical Co. Ltd.

Aska Pharmaceutical Co. Ltd.

Payment unspecified

5/31/18

Link Health to develop and commercialize Teikoku Pharma's Lidoderm for pain in China

Teikoku Pharma USA Inc.

Link Health Group

Payment unspecified

5/30/18

Antibody Solutions to use Trianni's Mouse in antibody discovery programs

Trianni Inc.

Antibody Solutions

Payment unspecified

5/22/18

Brii Biosciences to acquire greater China rights for up to four infectious disease assets from Vir Biotechnology

Vir Biotechnology Inc.

Brii Biosciences

Payment unspecified

5/24/18

Newsoara to develop and commercialize Vtv Therapeutics' HPP-737 for respiratory and other inflammatory diseases in mainland China, Hong Kong, Macau, Taiwan and other Pacific Rim countries

Vtv Therapeutics LLC

Newsoara Biopharma Co. Ltd.

Payment unspecified

5/31/18

Harbin Pharmaceutical to distribute Wize Pharma's LO2A for ophthalmic disorders in China

Wize Pharma Inc.

Harbin Pharmaceutical Group Co. Ltd.

Payment unspecified

5/31/18

Wuxi Biologics and Bioasis to develop and manufacture Xb-001 against brain cancer

Wuxi Biologics

Bioasis Technologies Inc.

Payment unspecified

5/21/18

Novarock Biotherapeutics to use Trianni's mouse in monoclonal antibody discovery research

Trianni Inc.

Novarock Biotherapeutics Ltd.

Payment unspecified

3/28/18

June

4D Pharma and MSD to evaluate the combination of Keytruda and MRX-0518 in a phase I study for solid tumors

4D Pharma plc

Merck Sharp and Dohme Corp.

Payment unspecified

6/7/18

E-scape to develop and commercialize Abbvie's S1P5 agonists for lysosomal storage disorders worldwide

Abbvie Inc.

E-scape Bio

Payment unspecified

6/12/18

Abcellera and Denali to discover monoclonal antibodies with specific binding properties against a genetically validated target for neurodegenerative disease

Abcellera Biologics Inc.

Denali Therapeutics Inc.

Payment unspecified

6/12/18

Abcheck to discover multiple human single-chain variable fragments for Molmed's targets against liquid and solid tumors

Abcheck s.r.o.

Molmed SpA

Payment unspecified

6/28/18

Gossamer to develop and commercialize Aerpio's AKB-4924 and other structurally related products against inflammatory bowel disease, initially for ulcerative colitis and Crohn's disease worldwide

Aerpio Pharmaceuticals Inc.

Gossamer Bio Inc.

$420.00

6/24/18

Cstone to develop and commercialize Agios' ivosidenib for acute myeloid leukemia and cholangiocarcinoma in mainland China, Hong Kong, Macau and Taiwan

Agios Pharmaceuticals Inc.

Cstone Pharmaceuticals Co. Ltd.

$424.00

6/26/18

Bridgebio to acquire Alexion's ALXN-1101 for molybdenum cofactor deficiency Type A

Alexion Pharmaceuticals Inc.

Bridgebio Pharma LLC

Unknown

6/11/18

Akero Therapeutics to develop Amgen's AKR-001 against nonalcoholic steatohepatitis

Amgen Inc.

Akero Therapeutics

Payment unspecified

6/25/18

Aptus to design clinical study for Artelo's ART-27.13 against oncology

Aptus Clinical Ltd.

Artelo Biosciences Inc.

Payment unspecified

6/12/18

Infinity Pharmaceuticals and Arcus Biosciences to evaluate two triple combination therapies against triple negative breast cancer and ovarian cancer

Arcus Biosciences Inc.

Infinity Pharmaceuticals Inc.

Unknown

6/26/18

BB200 to license Arsanis' ASN-300 for preclinical development against Klebsiella pneumoniae infection worldwide with an option for clinical development and commercialization

Arsanis Inc.

BB200 LLC

Payment unspecified

6/14/18

Athenex to develop and commercialize Polytom's pegylated genetically modified human arginase for cancer worldwide

Avalon Polytom Ltd.

Athenex Inc.

$50.00

6/29/18

Avella to distribute Array's combination therapy Braftovi and Mektovi for metastatic melanoma

Avella

Array Biopharma Inc.

Payment unspecified

6/28/18

Biologics to distribute Array's combination therapy Braftovi and Mektovi for metastatic melanoma

Biologics Inc.

Array Biopharma Inc.

Payment unspecified

6/29/18

Deinove and Biomerieux to discover antibiotics against bacterial infections

Biomerieux SA

Deinove SA

Payment unspecified

6/28/18

Goliver Therapeutics to use Biotime's pluripotent cell lines to advance therapeutic candidates against liver disease

Biotime Inc.

Goliver Therapeutics

Payment unspecified

6/25/18

BL&H to distribute Mediwound's Nexobrid for eschar removal in South Korea

BL&H Co. Ltd.

Mediwound Ltd.

Payment unspecified

6/4/18

Cstone Pharmaceuticals to develop and commercialize Blueprint Medicines' avapritinib, BLU-554 and BLU-667 in greater China

Blueprint Medicines Corp.

Cstone Pharmaceuticals Co. Ltd.

$386.00

6/1/18

Brammer Bio to support the manufacture of Sarepta's gene therapy programs against Duchenne muscular dystrophy and limb girdle muscular dystrophy

Brammer Biopharmaceuticals LLC

Sarepta Therapeutics Inc.

Payment unspecified

6/13/18

Cannabics Pharmaceuticals and an undisclosed biopharmaceutical company to establish a new Israeli entity for treating eye disorders using cannabinoids

Cannabics Pharmaceuticals Inc.

Undisclosed

Unknown

6/29/18

Clovis Oncology to sign a letter of intent with Immunomedics for the evaluation of Rubraca with sacituzumab against metastatic triple-negative breast cancer and metastatic urothelial cancer

Clovis Oncology Inc.

Immunomedics Inc.

Unknown

6/3/18

Alexion and Complement to develop CP-010 for neurodegenerative disorders

Complement Pharma

Alexion Pharmaceuticals Inc.

$17.20

6/11/18

CR Pharmaceutical to distribute Ascletis' Ganovo for hepatitis C in China

CR Pharma

Ascletis Pharmaceutical Co. Ltd.

Payment unspecified

6/26/18

Crownbio to provide services to accelerate Pierre-Fabre's immuno-oncology drug discovery

Crown Bioscience Inc.

Pierre-Fabre Research Institute

Payment unspecified

6/19/18

A. Menarini Asia-Pacific to commercialize Daiichi Sankyo's edoxaban in the Philippines, Malaysia and Singapore

Daiichi Sankyo Co. Ltd.

A. Menarini Asia-Pacific Holdings Pte. Ltd.

Payment unspecified

6/28/18

Apac Biotech to develop Diakonos Research's immunotherapy technology for solid tumors in India

Diakonos Research Ltd.

Apac Biotech Pvt. Ltd.

Payment unspecified

6/22/18

Tasly to develop and commercialize EA Pharma's AJT-240 for secondary hyperparathyroidism in China

EA Pharma Co. Ltd.

Tasly Pharmaceutical Group Co. Ltd.

Payment unspecified

6/12/18

Nico Innovapharma to sign a memorandum of understanding with Eastgate to commercialize insulin mouth rinse for type 2 diabetes in Europe

Eastgate Biotech Corp.

Nico Innovapharma

$38.00

6/19/18

Cipla to distribute Lilly's Basaglar for type 1 and 2 diabetes in India

Eli Lilly and Company (India) Pvt. Ltd.

Cipla 

Payment unspecified

6/8/18

Devonian Health to enter a letter of intent to develop Folia's FB-631 as an immunotherapeutic platform

Folia Biotech Inc.

Devonian Health Group Inc.

Payment unspecified

6/28/18

Taiwan Specialty Pharma to commercialize GNT's chidamide against breast cancer and peripheral T-cell lymphoma in Taiwan

GNT Biotech and Medicals Corp.

Taiwan Specialty Pharma Corp.

$1.02

6/21/18

Lakepharma to use Harbour's H2L2 transgenic mouse platform for discovery of human antibodies

Harbour Antibodies BV

Lakepharma Inc.

Payment unspecified

6/5/18

Hookipa Biotech and Gilead Sciences to develop immunotherapies against human immunodeficiency virus and hepatitis B virus infections

Hookipa Biotech AG

Gilead Sciences Inc.

$410.00

6/5/18

Horizon to grant manufacture and commercialization rights to Lupin for generic version of Ravicti in litigation settlement

Horizon Pharma plc

Lupin Ltd.

Payment unspecified

6/27/18

Iason to manufacture and distribute Blue Earth Diagnostics' positron emission tomography imaging product, Axumin to detect recurrence of prostate cancer in Poland

Iason Sp. z o.o.

Blue Earth Diagnostics Ltd.

Payment unspecified

6/25/18

Bionet-Asia and ICA to develop pentavalent DNA vaccine against dengue and Zika infection using Nanotaxi nanocarrier technology

In-Cell-Art SAS

Bionet-Asia Co. Ltd.

Payment unspecified

6/19/18

LG Chem to discover therapeutic oncology leads using Iontas' antibody discovery platforms

Iontas Ltd.

LG Chem Ltd.

Payment unspecified

6/5/18

Nicox and Ironwood Pharmaceuticals to identify therapeutics for the treatment of certain ophthalmic conditions

Ironwood Pharmaceuticals Inc.

Nicox SA

Payment unspecified

6/6/18

Isoplexis to evaluate the impact of Nektar's NKTR-214 against cancer using Isocode chip technology

Isoplexis Corp.

Nektar Therapeutics

Payment unspecified

6/26/18

Alliance Pharma to market Janssen's Nizoral, an anti-dandruff shampoo, in the Asia-Pacific region

Janssen Pharmaceutica NV

Alliance Pharma plc

$83.47

6/19/18

Kramer Laboratories acquiring Nizoral from Janssen to treat dandruff

Janssen Pharmaceutica NV

Kramer Laboratories Inc.

Payment unspecified

6/25/18

Saladax Biomedical to use Janssen's patents related to companion diagnostics for antipsychotic medications worldwide

Janssen Pharmaceutica NV

Saladax Biomedical Inc.

Payment unspecified

6/26/18

Tersera Therapeutics to purchase Jazz Pharmaceuticals' Prialt for chronic pain

Jazz Pharmaceuticals plc

Tersera Therapeutics LLC

$80.00

6/29/18

Novo Nordisk to develop and commercialize Kallyope's peptides for obesity and diabetes worldwide

Kallyope Inc.

Novo Nordisk A/S

Payment unspecified

6/19/18

Kangpu and Accelovance to evaluate KPG-121 in combination with enzalutamide in adults with metastatic castration-resistant prostate cancer

Kangpu Biopharmaceuticals Inc.

Accelovance Inc.

Payment unspecified

6/27/18

Kymab and Roche to evaluate KY-1044 in combination with atezolizumab against multiple tumors

Kymab Ltd.

F. Hoffmann-La Roche AG

Payment unspecified

6/28/18

Virpax to develop Lipocure's LBL-100 for pain using liposome drug delivery technology

Lipocure Ltd.

Virpax Pharmaceuticals Inc.

Payment unspecified

6/4/18

Nichi-Iko to distribute Lupin's etanercept against inflammatory conditions in Japan

Lupin Ltd.

Nichi-Iko Pharmaceutical Co. Ltd.

Payment unspecified

6/18/18

Mylan to commercialize Lupin's Enbrel biosimilar in Europe, Australia, New Zealand, Latin America, Africa and most Asian markets

Lupin Ltd.

Mylan Inc.

$15.00

6/28/18

Aytu to commercialize Magna's Zolpimist for insomnia in the U.S. and Canada

Magna Pharmaceuticals Inc.

Aytu Bioscience Inc.

Payment unspecified

6/11/18

Meiji Seika Pharma and Two Cells to discover a novel cell therapy for osteoarthritis

Meiji Seika Pharma Co. Ltd.

Two Cells Co. Ltd.

Payment unspecified

6/26/18

Microbiotica and Genentech to discover, develop and commercialize biomarkers, targets and medicines for inflammatory bowel disease

Microbiotica Ltd.

Genentech Inc.

$534.00

6/6/18

Hyundai to commercialize Mithra's Estelle as an oral contraceptive in South Korea

Mithra Pharmaceuticals SA

Hyundai Pharmaceutical Co. Ltd.

Payment unspecified

6/5/18

Orifarm to commercialize Mithra's Myring for contraception in Denmark

Mithra Pharmaceuticals SA

Orifarm Group A/S

Payment unspecified

6/21/18

Amarin and Mochida to develop and commercialize omega-3 acid eicosapentaenoic acid-based candidates against cardiovascular diseases in the U.S. and other territories

Mochida Pharmaceutical Co. Ltd.

Amarin Corp. plc

$2.70

6/12/18

Mystic to manufacture East Gate's insulin mouth rinse solution for type 2 diabetes

Mystic Pharmaceuticals Ltd.

East Gate Pharmaceuticals

Payment unspecified

6/21/18

Fortify to develop Neurovive's NVP-015 for Leber's hereditary optic neuropathy

Neurovive Pharmaceutical AB

Fortify Therapeutics Inc.

$60.00

6/18/18

Respirerx to enter a letter of intent with Noramco to co-develop and supply dronabinol against obstructive sleep apnea

Noramco Inc.

Respirerx Pharmaceuticals Inc.

Payment unspecified

6/13/18

TG Therapeutics and Novimmune to develop and commercialize TG-1801 for hematologic B-cell malignancies worldwide

Novimmune SA

TG Therapeutics Inc.

$188

6/18/18

Oncobiologics to manufacture Sonnet's monoclonal antibodies

Oncobiologics Inc.

Sonnet Biotherapeutics Inc.

Payment unspecified

6/13/18

Erydel to develop Orphan Technologies' EE-TP for mitochondrial neurogastrointestinal encephalopathy using automated autologous red blood cell technology

Orphan Technologies Ltd.

Erydel SpA

Payment unspecified

6/4/18

Axovant to develop and commercialize Oxford's OXB-102 and its predecessor product Prosavin for Parkinson's disease worldwide

Oxford Biomedica plc

Axovant Sciences Ltd.

$842.50

6/5/18

Nuance Biotech to develop and commercialize Pacira's Exparel for pain in China

Pacira Pharmaceuticals Inc.

Nuance Biotech Inc.

$58.00

6/19/18

Pantherx to distribute Ultragenyx Pharmaceutical's Crysvita for X-linked hypophosphatemia

Pantherx Specialty Pharmacy

Ultragenyx Pharmaceutical Inc.

Payment unspecified

6/7/18

Pint Pharma to commercialize Pharmamar's Aplidin against hematological cancer in Latin America

Pharmamar SA

Pint Pharma GmbH

Payment unspecified

6/11/18

Phoremost and Oxygen Healthcare to develop drugs using siteseeker phenotypic screening platform

Phoremost Ltd.

Oxygen Healthcare

Payment unspecified

6/21/18

Premier Research to conduct phase III study for Infant Bacterial Therapeutics' IBP-9414 against necrotizing enterocolitis

Premier Research Group Ltd.

Infant Bacterial Therapeutics AB

Payment unspecified

6/26/18

Alvogen to commercialize Prestige Biopharma's HD-201 in Central and Eastern Europe

Prestige Biopharma

Alvogen Inc.

Payment unspecified

6/28/18

Ohara to develop, manufacture and commercialize Prism Pharma's PRI-724 injection for the treatment of fibrosis including cirrhosis in Japan

Prism Pharma Co. Ltd.

Ohara Pharmaceutical Co. Ltd.

Payment unspecified

5/24/18

Champions to develop patient derived xenograft tumor models for Puma's neratinib against metastatic breast and colon cancer

Puma Biotechnology Inc.

Champions Oncology Inc.

Payment unspecified

6/18/18

Recipharm divests Thyrosafe rights to Serb except in the U.S.

Recipharm AB

Serb SA

$11.67

6/14/18

Redhill Biopharma to co-promote Napo's Mytesi against diarrhea in the U.S.

Redhill Biopharma Ltd.

Napo Pharmaceuticals Inc.

Payment unspecified

6/28/18

Zoetis to use Regeneron' VelocImmune technology to develop monoclonal antibodies against allergy, osteoarthritis and immune disorders

Regeneron Pharmaceuticals Inc.

Zoetis Inc.

Payment unspecified

6/6/18

Shionogi to develop and commercialize Sage's SAGE-217 for major depressive disorder in Japan, Taiwan and South Korea

Sage Therapeutics Inc.

Shionogi & Co. Ltd.

$575.00

6/12/18

Salix to co-promote U.S. Worldmeds' Lucemyra for mitigation of opioid withdrawal symptoms in the U.S.

Salix Pharmaceuticals Inc.

U.S. Worldmeds LLC

Payment unspecified

6/26/18

Simbec-Orion to conduct a phase II study for Acticor Biotech's ACT-017 against acute ischemic stroke

Simbec-Orion Group Ltd.

Acticor Biotech

Payment unspecified

6/14/18

Skyhawk and Celgene to discover mRNA splicing modifiers using STAR* technology for neurological diseases with worldwide license option

Skyhawk Therapeutics

Celgene Corp.

$60

6/26/18

EMS to distribute Sonoma Pharmaceuticals' dermatology products in Brazil

Sonoma Pharmaceuticals Inc.

EMS SA

Payment unspecified

6/4/18

Syngene to provide discovery and development services for Artelo Biosciences' ART27.13 against oncology

Syngene International Ltd.

Artelo Biosciences Inc.

Payment unspecified

6/12/18

Endo International to distribute Takeda's Colcrys 0.6 mg tablets against gout flares and Mediterranean fever in the U.S.

Takeda Pharmaceutical Co. Ltd.

Endo International plc

Payment unspecified

7/2/18

Isologic to manufacture Telix's TLX-250 for clinical trials in North America and commercialize it in Canada for the imaging of clear cell renal cell carcinoma

Telix Pharmaceuticals Ltd.

Isologic Innovative Radiopharmaceuticals Ltd.

Payment unspecified

6/25/18

Tesaro to divest North American rights of oral and intravenous formulations of Varubi to Tersera

Tesaro Inc.

Tersera Therapeutics LLC

$60.00

6/28/18

Alvogen to distribute certain Theramex women's health products in Russia, Central and Eastern Europe as well as countries within the Commonwealth of Independent States

Theramex

Alvogen Inc.

Payment unspecified

6/25/18

Biogen to obtain an option to acquire TMS' TMS-007 and backup compounds for acute stroke

TMS Co. Ltd.

Biogen Inc.

$357.00

6/7/18

Tonghua to manufacture and supply insulin lispro and insulin glargine active pharmaceutical ingredients to Adocia worldwide, excluding China

Tonghua Dongbao Pharmaceutical Co. Ltd.

Adocia SAS

Payment unspecified

6/1/18

Translate Bio and Sanofi to develop vaccines using mRNA technology for infectious diseases worldwide

Translate Bio

Sanofi SA

$805.00

6/11/18

Straterx to use Trianni's Mouse to develop a fully human monoclonal antibody for oncology

Trianni Inc.

Straterx Inc.

Payment unspecified

6/12/18

U.S. Bioservices to distribute Rigel's Tavalisse tablets for immune thrombocytopenia in the U.S.

U.S. Bioservices

Rigel Pharmaceuticals Inc.

Payment unspecified

6/18/18

U.S. Bioservices to dispense Array Biopharma's binimetinib and encorafenib in the U.S.

U.S. Bioservices Corp.

Array Biopharma Inc.

Payment unspecified

6/28/18

Yakult Honsha to develop and commercialize Verastem's duvelisib for all oncology indications in Japan

Verastem Oncology

Yakult Honsha Co. Ltd.

$100.00

6/5/18

Veritas Pharma and Foliumed to sign a memorandum of understanding for the development and commercialization of medical cannabis products

Veritas Pharma Inc.

Foliumed SAS

Payment unspecified

6/18/18

Wuxi to manufacture and develop Harbour's HCAbs against cancer

Wuxi Biologics

Harbour Biomed

Payment unspecified

6/24/18

Athenex and Xlifesc to establish a joint venture, Axis Therapeutics, to research, develop and commercialize T-cell receptor-engineered T-cell immunotherapies for cancer

Xiangxue Life Science Research Center

Athenex Inc.

$5

6/29/18

July

Medimmune and 4DMT to design, develop and commercialize a gene therapeutic for patients with chronic lung disease

4D Molecular Therapeutics LLC

Medimmune LLC

Payment unspecified

7/10/18

Mylan to acquire intellectual property rights from Abbvie related to biosimilar adalimumab worldwide excluding Europe

Abbvie Inc.

Mylan Inc.

Payment unspecified

7/17/18

Trigr Therapeutics to develop and commercialize ABL Bio's antibodies for cancer worldwide excluding South Korea

ABL Bio Inc.

Trigr Therapeutics

$554.30

7/2/18

Sandoz to commercialize Adamis' Symjepi for allergy including anaphylaxis in the U.S.

Adamis Pharmaceuticals Corp.

Sandoz Inc.

Payment unspecified

7/1/18

APC and Noria to test linker technology with Macropa radioisotope chelation technology in combination with antibodies for cancer

Advanced Proteome Therapeutics Inc.

Noria Pharmaceuticals Inc.

Payment unspecified

7/17/18

Sandoz to commercialize Aequus's Vistitan for glaucoma in Canada

Aequus Pharmaceuticals Inc.

Novartis AG

Unknown

7/16/18

Lynkogen to develop and commercialize Alteogen's GLP-1/A1AT fusion proteins against nonalcoholic steatohepatitis and metabolic diseases worldwide, excluding Korea

Alteogen Inc.

Lynkogen Inc.

Payment unspecified

7/1/18

Antoxerene and Juvenescence to form a joint venture, Foxbio to develop small molecule drugs for diseases of aging

Antoxerene Inc.

Juvenescence Ltd.

Unknown

7/12/18

Kalytera to acquire all rights of BPL's medical cannabis products worldwide

Beetlebung Pharma Ltd.

Kalytera Therapeutics Inc.

$0.05

7/19/18

Axovant to develop and commercialize Benitec's BB-301 for oculopharyngeal muscular dystrophy worldwide

Benitec Biopharma Ltd.

Axovant Sciences GmbH

$665

7/8/18

Bioagilytix and Bioasis to support and advance xB3-001 and define the clinical dose to treat HER2+ brain cancer

Bioagilytix Labs LLC

Bioasis Technologies Inc.

Payment unspecified

7/11/18

Prevacus to conduct a phase I clinical trial of PRV-002 using Blinktbi's Eyestat for concussion

Blinktbi Inc.

Prevacus Inc.

Payment unspecified

7/13/18

Corerx to manufacture Innovation Pharmaceuticals' brilacidin for oral mucositis

Corerx Inc.

Innovation Pharmaceuticals Inc.

Payment unspecified

7/17/18

Theramex to market Endoceutics' Intrarosa for vulvar and vaginal atrophy in postmenopausal women in Australia, Russia and selected countries in the Commonwealth of Independent States and Europe

Endoceutics Inc.

Theramex

Payment unspecified

7/19/18

Locus acquiring Epibiome's bacteriophage discovery platform to develop products, including ADJ-02, against antibiotic-resistant bacterial infections worldwide

Epibiome Inc.

Locus Biosciences

Payment unspecified

7/17/18

Serb Pharmaceuticals to acquire Eusa Pharma's critical care business including collatamp

Eusa Pharma

Serb Pharmaceuticals

Payment unspecified

7/11/18

Kite Pharma and Gadeta to develop gamma delta T-cell receptor therapies in various cancers, with an option to acquire Gadeta

Gadeta BV

Kite Pharma Inc.

Payment unspecified

7/19/18

Novartis to develop and commercialize Galapagos' MOR-106 for atopic dermatitis and other indications worldwide

Galapagos NV

Novartis AG

$563.35

7/19/18

Biontech and Genevant Sciences to co-develop five mRNA therapeutic programs for rare diseases

Genevant Sciences Ltd.

Biontech AG

Payment unspecified

7/10/18

Genexine and Merck to conduct a phase Ib/II study to evaluate the combination of Hyleukin-7 with Keytruda for triple-negative breast cancer

Genexine Co. Ltd.

Merck & Co. Inc.

Payment unspecified

7/18/18

Dermavant to acquire Glaxosmithkline's tapinarof for psoriasis and atopic dermatitis worldwide except China, as well as back-up programs

Glaxosmithkline plc

Dermavant Sciences Inc.

$340.12

7/12/18

Seqirus to commercialize Glenmark's Ryaltris for seasonal allergic rhinitis in Australia and New Zealand

Glenmark Pharmaceuticals SA

Seqirus Pty Ltd.

Payment unspecified

7/6/18

Gritstone to evaluate GRANITE-001 in combination with BMS' Opdivo and Yervoy against advanced solid tumor

Gritstone Oncology

Bristol-Myers Squibb Co.

Payment unspecified

7/19/18

Undisclosed major biopharmaceutical company to study GT Biopharma's OXS-1550 in combination with an oncology drug

GT Biopharma Inc.

Undisclosed

Payment unspecified

7/19/18

Highmark and Boehringer to collaborate on an outcomes-based contract related to Jardiance

Highmark Inc.

Boehringer Ingelheim International GmbH

Payment unspecified

7/10/18

Dare Bioscience to acquire patents related to Catsper ion channel from Hydra Biosciences

Hydra Biosciences Inc.

Dare Bioscience Inc.

Payment unspecified

7/16/18

Ibio to provide process development and manufacturing services to CC-Pharming to develop products including rituximab

Ibio Inc.

CC-Pharming Ltd.

$4.70

7/9/18

Genmab and Immatics Biotechnologies to discover and develop next-generation bispecific cancer immunotherapies using Xpresident technology worldwide

Immatics Biotechnologies GmbH

Genmab A/S

$1,704.00

7/12/18

Eusa Pharma to acquire worldwide rights to Janssen Sciences' Sylvant against idiopathic multicentric Castleman disease

Janssen Sciences Ireland UC

Eusa Pharma

$115.00

7/18/18

Astellas Pharma and KM Biologics to market influenza hemagglutinin vaccine in Japan

KM Biologics Co. Ltd.

Astellas Pharma Inc.

Payment unspecified

7/2/18

Meiji Holdings and KM Biologics to market influenza hemagglutinin vaccine in Japan

KM Biologics Co. Ltd.

Meiji Holdings Co. Ltd.

Payment unspecified

7/2/18

Takeda to use Leon-Nanodrug's microjet reactor nano technology to assess and develop an innovative formulation from pipeline products

Leon-Nanodrugs GmbH

Takeda Pharmaceutical Co. Ltd.

Payment unspecified

7/17/18

Nissan Chemical and Luxna Biotech to discover and develop oligonucleotides therapeutics

Luxna Biotech Co. Ltd.

Nissan Chemical Corp.

Payment unspecified

7/6/18

Y-mabs to develop Mabvax's MV-NB-02 vaccine for neuroblastoma

Mabvax Therapeutics Holdings Inc.

Y-mabs Therapeutics Inc.

$1.30

7/3/18

Vyriad to evaluate Voyager-V1 in combination with Merck's avelumab against metastatic colorectal cancer in a phase I clinical trial

Merck KGaA

Vyriad

Payment unspecified

7/18/18

Tasly to develop Mesoblast's MPC-150-IM and MPC-25-IC against chronic heart failure and acute myocardial infarction in China

Mesoblast Ltd.

Tasly Pharmaceutical Group Co. Ltd.

$65.00

7/17/18

Zhuhai Essex to commercialize Mitotech's SkQ1 ophthalmic solution against dry eye disease and uveitis in Singapore and greater China

Mitotech SA

Zhuhai Essex Bio-Pharmaceutical Co. Ltd.

Payment unspecified

7/16/18

Novartis to develop and commercialize Morphosys' MOR-106 for atopic dermatitis and other indications worldwide

Morphosys AG

Novartis AG

$563.35

7/19/18

Mundipharma to develop and commercialize Neovii's Grafalon for graft-versus-host disease in China and Japan

Neovii Pharmaceuticals AG

Mundipharma International Corp. Ltd.

Payment unspecified

7/5/18

Adlai Nortye Biopharma to develop and commercialize Novartis' buparlisib against cancer worldwide

Novartis AG

Adlai Nortye Pharmaceutical Co. Ltd.

Payment unspecified

7/10/18

Clinigen acquires worldwide rights o Novartis' Proleukin against metastatic renal cell carcinoma and metastatic melanoma excluding the U.S.

Novartis AG

Clinigen Group plc

Payment unspecified

7/17/18

Onco360 to distribute Array's combination therapy Braftovi and Mektovi for unresectable or metastatic melanoma

Onco360

Array Biopharma Inc.

Payment unspecified

7/2/18

Terumo to commercialize Piramal's fentanyl injection for pain in Japan

Piramal Critical Care Ltd.

Terumo Corp.

Payment unspecified

7/5/18

Pluristem and Thermo Fisher to advance cell therapy industrialization and improve quality control of end-to-end supply chain

Pluristem Therapeutics Inc.

Thermo Fisher Scientific Inc.

Payment unspecified

7/9/18

Puretech and Roche to develop milk-derived exosome technology for the oral administration of antisense oligonucleotide

Puretech Health plc

Roche Holding AG

$1,036.00

7/20/18

Shandong Danhong to develop Remd Biotherapeutics' REMD-288 and REMD-290 for cancer worldwide

Remd Biotherapeutics Inc.

Shandong Danhong Pharmaceutical Co. Ltd.

$15.00

7/13/18

U.S.-based specialty pharma company to license Reneuron's human retinal progenitor cell technology and ReN-003 worldwide excluding China

Reneuron Group plc

Undisclosed

$5.00

7/11/18

Sinovant to develop and commercialize Renexxion's naronapride in China, Hong Kong, Macau and Taiwan, initially for inflammatory bowel disease with constipation

Renexxion

Sinovant Sciences Ltd.

Payment unspecified

7/17/18

Sanofi and Revolution Medicines to develop and commercialize SHP2 inhibitors, including RMC-4630, for non-small-cell lung cancer and other cancers worldwide

Revolution Medicines Inc.

Sanofi SA

$550.00

7/18/18

Shandong Danhong and Shanghai Yanyi to develop B-193 for lymphoma

Shanghai Yanyi Biotechnology Co. Ltd.

Shandong Danhong Pharmaceutical Co. Ltd.

$10.46

7/13/18

STA to provide development and manufacturing services to Antengene's clinical stage and commercial oncology and viral drugs

STA Pharmaceutical Co. Ltd.

Antengene Corp.

Payment unspecified

7/16/18

Teneobio and Janssen to develop multi-specific antibodies for undisclosed oncology targets using the Unirat platform and the Teneoseek sequence-based discovery engine worldwide

Teneobio Inc.

Janssen Biotech Inc.

Payment unspecified

7/9/18

Tetra Bio-Pharma and Storz & Bickel to study PPP-001 in combination with Mighty Medic against fibromyalgia and other chronic pain conditions

Tetra Bio-Pharma Inc.

Storz & Bickel GmbH & Co. KG

Payment unspecified

7/16/18

Cure to sign a non-binding term sheet to acquire Therapix's cannabinoid-based drug pipeline

Therapix Biosciences Ltd.

Cure Pharmaceutical Inc.

Payment unspecified

7/11/18

TD2 to conduct preclinical studies for Atossa's chimeric antigen receptor T-cell therapy using intraductal microcatheter technology against breast cancer

Translational Drug Development

Atossa Genetics Inc.

Payment unspecified

7/18/18

Dr. Reddy's to co-promote and distribute UCB's Briviact for epilepsy in India

UCB SA

Dr. Reddy's Laboratories Ltd.

Payment unspecified

7/9/18

Wuxi to provide development and commercial manufacturing for Immune Pharmaceuticals' bertilimumab for bullous pemphigoid

Wuxi Biologics

Immune Pharmaceuticals Inc.

Payment unspecified

7/9/18

Stada and Xbrane to co-develop and commercialize Xlucane biosimilar for wet age-related macular degeneration in Europe, the U.S. and a variety of Middle East, North African and Asia Pacific markets

Xbrane Biopharma AB

Stada Arzneimittel AG

$8.94

7/12/18

Xintela and Co.don to sign a letter of intent to establish a joint venture to develop a stem cell product for osteoarthritis in Europe and North America

Xintela AB

Co.don AG

Unknown

7/9/18

Zander and Ampersand to develop therapeutics for various disorders including arthritis, atopic dermatitis and cancer in companion animals

Zander Therapeutics Inc.

Ampersand Biopharmaceuticals Inc.

Unknown

7/5/18


Notes

This chart includes only biopharmaceutical deals between companies. Deals with universities and nonprofit entities, as well as mergers and acquisitions, will be highlighted in separate charts. For more information about individual companies and/or products, see Cortellis.