"Hopefully we'll have a treatment in the not-to-distant future for these women with an 80% risk of developing cancer. But surgery is an inevitable choice if they have no other viable alternative. It's not such a radical option because it's more radical to face chemotherapy and surgery to remove cancer."

— D. Gareth Evans, MD, consultant in clinical genetics at the Genesis Prevention Center, University Hospital of South Manchester NHS Trust on a study he did on women's choices when faced with genetic testing results that reveal their potential cancer causing mutations, "Women with high cancer risk opting for preventive surgery."