Biotech Co.* (Country; Symbol) Pharma Co. (Country) Change from original agreement Terms/Details (Date)
Bio-Rad Laboratories Inc. (AMEX:BIO) Beckman Coulter Inc. Extended for eight years their development and manufacturing agreement in immunodiagnostic testing for blood virus and infectious disease Bio-Rad will develop new immunoassays for Beckman Coulter's UniCel and Access immunoassay systems, including hepatitis B envelope antigen and antibody, to be used as indicators of chronic hepatitis or active infection (5/31)
Inspire Pharmaceuticals Inc. (ISPH) FAES Farma SA (Spain) Amended licensing agreement for the U.S. and Canadian development and commercialization of oral bilastine to treat allergic rhinitis FAES has agreed to conduct additional clinical work and an expanded QT/QTc comparative trial (6/20)
Memory Pharmaceuticals Corp. (MEMY) F. Hoffmann-La Roche Ltd. (Switzerland) Expanded development agreement for MEM3454 to treat cognitive impairment associated with schizophrenia Further details were not disclosed (6/19)
Altus Pharmaceuticals Inc. (ALTU) Dr. Falk Pharma GmbH (Germany) Terminated agreement for ALTU-135 Companies ended their development and commercialization collaboration in Europe and countries of the former Soviet Union, Israel and Egypt; Dr. Falk will transfer the orphan medicinal product designation and Altus will pay $16M over three years (6/11)
Coley Pharmaceutical Group Inc. (COLY) Pfizer Inc. Terminated agreement for the lung cancer drug, PF-3512676 The decision to terminate was made after the product showed no evidence of clinical efficacy in Phase III trials (6/20)
Icagen Inc. (ICGN) McNeil Consumer & Specialty Pharmaceuticals (subsidiary of Johnson & Johnson) Terminated partnership for senicapoc In April, Icagen halted a Phase III trial of senicapoc in adults with sickle cell disease after a data monitoring committee said the trial was unlikely to meet its primary endpoint of reducing crisis rate (6/22)

# The information in the chart does not cover agreements between biotech companies or agricultural agreements.
* Private companies are indicated with an asterisk.
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