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BioWorld - Tuesday, June 17, 2025
Home » Topics » Regulatory » Patents

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Endocrine/metabolic

Ascletis Pharma discovers new GLP-1R agonists

June 17, 2025
Ascletis Pharma (China) Co. Ltd. has described glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), diabetes, obesity, metabolic syndrome and more.
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Cancer

New PARG inhibitors disclosed in 858 Therapeutics patent

June 17, 2025
858 Therapeutics Inc. has divulged poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Ariel Scientific Innovations describes new dolastatin 10 analogues and conjugates

June 17, 2025
Ariel Scientific Innovations Ltd. has identified dolastatin 10 analogues and its conjugates comprising another functional moiety and a linking moiety reported to be useful for the treatment of cancer.
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Neurology/psychiatric

University of Sydney divulges new TSPO ligands

June 17, 2025
University of Sydney has synthesized translocator protein (TSPO; PBR) (A147T mutant) ligands reported to be useful for the diagnosis and treatment of neurological disorders.
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Neurology/psychiatric

Biogen patents new HTT splicing modulators

June 17, 2025
Biogen Inc. has disclosed huntingtin (HTT; HD) (mutant) splicing modulators reported to be useful for the treatment of Huntington’s disease and spinal muscular atrophy (SMA).
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Neurology/psychiatric

Nanjing Mingde New Drug Research discovers new KCNQ2/3 activators

June 16, 2025
Nanjing Mingde New Drug Research Co. Ltd. has described potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators reported to be useful for the treatment of epilepsy.
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Cancer

New WRN inhibitors disclosed in Breakpoint Therapeutics patent

June 16, 2025
Breakpoint Therapeutics GmbH has divulged Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Rubedo Life Sciences describes new Bcl-xl inhibitors

June 16, 2025
Rubedo Life Sciences Inc. has identified Bcl-2-like protein 1 (Bcl-xl; Bcl-X; BCL2L1) inhibitors acting as senolytic agents reported to be useful for the treatment of autoimmune disease, cancer, cardiovascular disorders, cognitive disorders, diabetes, inflammatory, metabolic and neurological disorders, among others.
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Immune

Dana-Farber Cancer Institute patents new SHP-1 agonists

June 16, 2025
Dana-Farber Cancer Institute Inc. has synthesized tyrosine-protein phosphatase non-receptor type 6 (PTPN6; PTP-1C; SH-PTP1) activators reported to be useful for the treatment of autoimmune disease and cancer.
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Cancer

Haisco Pharmaceutical divulges new Raf kinase B mutant inhibitors

June 16, 2025
Haisco Pharmaceutical Group Co. Ltd. has disclosed Raf kinase B (V600E mutant) inhibitors reported to be useful for the treatment of cancer.
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