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BioWorld - Thursday, May 15, 2025
Home » Topics » Regulatory » Patents

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Dermatologic

Hepaitech (Beijing) Biopharma Technology discovers new MRGPRX4 antagonists

April 24, 2025
Hepaitech (Beijing) Biopharma Technology Co. Ltd. has described Mas-related G-protein coupled receptor member X4 (MRGPRX4; SNSR5; SNSR6) antagonists reported to be useful for the treatment of anemia, fungal infections, HIV infections, renal disorders, liver diseases, psoriasis, pruritus and urticaria, among others.
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Cancer

IKZF2 degradation and IKZF2/CRBN interaction inducers disclosed in Polymed patent

April 24, 2025
Hangzhou Polymed Biopharmaceuticals Inc. has divulged molecular glue degraders comprising cereblon (CRBN) binding agents covalently bound to a zinc finger protein Helios (IKZF2)-targeting moiety acting as IKZF2 degradation and IKZF2/CRBN interaction inducers.
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Cardiovascular

Bristol Myers Squibb describes new SGK1 inhibitors

April 24, 2025
Bristol Myers Squibb Co. has identified serum/glucocorticoid-regulated kinase 1 (SGK1) inhibitors reported to be useful for the treatment of fibrosis, cancer, cardiovascular, cerebrovascular, metabolic, inflammatory, neurological and immunological disorders, among others.
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Cancer

Isosterix divulges new KAT6A inhibitors

April 24, 2025
Isosterix Inc. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Synrx patents new PARG inhibitors for triple-negative breast cancer

April 24, 2025
Hangzhou Synrx Therapeutics Technology Co. Ltd. has disclosed poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of triple-negative breast cancer.
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Cancer

Hanmi Pharmaceutical discovers new SOS1 inhibitors

April 23, 2025
Hanmi Pharmaceutical Co. Ltd. has described son of sevenless homolog 1 (SOS1) inhibitors reported to be useful for the treatment of cancer.
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Cancer

MEN1/MLL interaction inhibitors disclosed in Beyond Therapeutics patent

April 23, 2025
Beyond Therapeutics Co. Ltd. has divulged menin (MEN1)/MLL interaction inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Bayer describes new α2C-adrenoceptor antagonists

April 23, 2025
Bayer AG has identified α2C-adrenoceptor antagonists reported to be useful for the treatment of dysphagia, snoring, neurodegeneration, neuroinflammation and cardiovascular disorders.
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Gastrointestinal

Bristol Myers Squibb divulges new RIPK1 inhibitors

April 23, 2025
Bristol Myers Squibb Co. has synthesized receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of inflammatory bowel disease, psoriasis, rheumatoid arthritis, nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), multiple sclerosis, amyotrophic lateral sclerosis, heart failure and Alzheimer’s disease.
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Inflammatory

Chengdu Chipscreen Pharmaceutical patents new integrin αvβ1 and αvβ6 antagonists

April 23, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has disclosed integrin αvβ1 and/or αvβ6 antagonists reported to be useful for the treatment of fibrosis.
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