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Home » Topics » Regulatory » Patents

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Inflammatory

US researchers describe new guanylate cyclase B receptor PAMS

May 28, 2025
Mayo Foundation for Medical Education and Research (MFMER) and University of Florida have identified atrial natriuretic peptide B (NPR2; guanylate cyclase B) receptor positive allosteric modulators (PAMs) reported to be useful for the treatment of fibrosis.
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Endocrine/metabolic

Université de Montréal divulges new compounds for cancer and Menkes disease

May 28, 2025
Université de Montréal has synthesized compounds reported to be useful for the treatment of cancer and Menkes disease.
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Cancer

University of Michigan patents new prodrugs of STING agonists

May 28, 2025
University of Michigan has disclosed prodrugs of stimulator of interferon genes protein (STING; TMEM173) agonists reported to be useful for the treatment of cancer, autoimmune disease, inflammatory disorder and infections.
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Neurology/psychiatric

Otsuka Pharmaceutical discovers new CSF1R inhibitors

May 27, 2025
Otsuka Pharmaceutical Co. Ltd. has described macrophage colony-stimulating factor 1 receptor (CSF1R; CD115; c-Fms) inhibitors reported to be useful for diagnosis and treatment of pain, infections, amyotrophic lateral sclerosis, multiple sclerosis, cardiovascular disorders, Alzheimer’s disease and Parkinson’s disease, among others.
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Immune

AhR agonists disclosed in Lilly patent

May 27, 2025
Eli Lilly & Co. has divulged aryl hydrocarbon receptor (AhR) agonists reported to be useful for the treatment of psoriasis, atopic dermatitis, ulcerative colitis, Crohn’s disease, graft-versus-host disease, rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis.
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Cancer

Betta Pharmaceuticals describes new GTPase KRAS mutant inhibitors

May 27, 2025
Betta Pharmaceuticals Co. Ltd. has identified GTPase KRAS mutant inhibitors reported to be useful for the treatment of cancer.
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Cancer

Bpgbio divulges new ESR1 degradation inducers

May 27, 2025
Bpgbio Inc. has synthesized bifunctional compounds comprising an E2 ubiquitin ligase binding ligand covalently linked to an estrogen receptor α (ER-α; ESR1) targeting moiety through a linker acting as ESR1 degradation inducers reported to be useful for the treatment of cancer.
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Cancer

Dong-A ST patents new YAP1/TEAD interaction inhibitors

May 27, 2025
Dong-A ST Co. Ltd. has disclosed transcriptional enhancer factor (TEAD) and/or transcriptional coactivator YAP1/TEAD interaction inhibitors reported to be useful for the treatment of cancer.
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Respiratory

Enanta Pharmaceuticals discovers new 17β-HSD13 inhibitors

May 26, 2025
Enanta Pharmaceuticals Inc. has described 17β-hydroxysteroid dehydrogenase 13 (HSD17B13; 17β-HSD13) inhibitors reported to be useful for the treatment of liver (hepatocellular carcinoma) cancer, cirrhosis, idiopathic pulmonary fibrosis and nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH).
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Cancer

New PI3K inhibitors disclosed in Hinova patent

May 26, 2025
Hinova Pharmaceuticals Inc. has divulged phosphatidylinositol 3-kinase (PI3K) inhibitors reported to be useful for the treatment of cancer.
Read More
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