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Home » Topics » Regulatory » Patents

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Infection

Latvian Institute of Organic Synthesis describes new PfSUB1 inhibitors for malaria

July 9, 2025
Latvian Institute of Organic Synthesis has identified subtilisin-like protease 1 (PfSUB1) (Plasmodium falciparum) inhibitors reported to be useful for the treatment of malaria.
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Neurology/psychiatric

Idorsia Pharmaceuticals divulges new orexin OX2 receptor agonists

July 9, 2025
Idorsia Pharmaceuticals Ltd. has synthesized aryl sulfone and sulfanone derivatives acting as orexin OX2 receptor agonists reported to be useful for the treatment of eating disorders, fatigue, Kleine-Levin syndrome, narcolepsy, obesity, pain, and psychiatric and inflammatory disorders, among others.
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Inflammatory

Lilly and Evotec patent new ROCK2 inhibitors

July 9, 2025
Eli Lilly & Co. and Evotec International GmbH have disclosed Rho-associated protein kinase 2 (ROCK2) inhibitors reported to be useful for the treatment of cancer, autoimmune disease, fibrosis, and inflammatory and neurological disorders.
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Neurology/psychiatric

Grünenthal discovers new Nav1.8 blockers

July 8, 2025
Grünenthal GmbH has described sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for the treatment of pain.
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Neurology/psychiatric

Ferroptosis inhibitors for mitochondrial disease disclosed in Acurex patent

July 8, 2025
Acurex Biosciences Corp. has divulged fused quinone compounds acting as ferroptosis inhibitors reported to be useful for the treatment of mitochondrial disease.
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Cancer

Deciphera Pharmaceuticals describes new PIK3C3 inhibitors

July 8, 2025
Deciphera Pharmaceuticals LLC has identified phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3; Vps34) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Alterome Therapeutics divulges new AKT1 inhibitors

July 8, 2025
Alterome Therapeutics Inc. has synthesized RAC-α serine/threonine-protein kinase (AKT1; PKB α) (E17K mutant) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Beijing Konruns Pharmaceutical patents new YES1 inhibitors

July 8, 2025
Beijing Konruns Pharmaceutical Co. Ltd. has disclosed tyrosine-protein kinase yes (YES1) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Design Therapeutics discovers new transcription modulators for DM1 and Fuchs’ dystrophy

July 7, 2025
Design Therapeutics Inc. has described transcription modulators reported to be useful for the treatment of myotonic dystrophy type 1 (DM1) and Fuchs’ dystrophy.
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Cancer

New CDK2 inhibitors disclosed in Ensem Therapeutics patent

July 7, 2025
Ensem Therapeutics has divulged compounds acting as cyclin-dependent kinase 2 (CDK2) inhibitors reported to be useful for the treatment of cancer.
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