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Home » Newsletters » BioWorld

BioWorld

May 18, 2018

View Archived Issues

As research definition of Alzheimer's changes, clinicians debate

The April announcement of a biomarker-based diagnosis for Alzheimer's disease by the National Institute of Aging (NIA) and the Alzheimer's Association (AA) came with assurances that their recommendations were meant as a "research framework to investigate the Alzheimer's disease continuum, not as diagnostic criteria and explicitly not intended for clinical use." Read More

Biotech shouldering past med tech as growth sector for Israel economy

TEL AVIV, Israel – Long focused on powering its depth of technological knowhow to develop strong med tech, Israel is now increasingly looking toward biotech as a pillar of growth for its health care industry and for the economy as a whole. Read More

Financings

Ligand Pharmaceuticals Inc., of San Diego, said it intends to offer $650 million in convertible senior notes due 2023 in a private offering to qualified institutional buyers. Read More

Other news to note

Toolgen Inc., of Seoul, South Korea, presented data demonstrating that blocking a molecular pathway that down-regulates T-cell activity with the company's CRISPR/Cas9 gene editing platform results in increased T-cell receptor signaling in vitro and in improved antitumor activity when tested in a mouse glioblastoma tumor model. Read More

Sweeter pH balance sheet aiding Onconano's efforts: $11.7M gained via series A

Onconano Medicine Inc.'s $11.7 million in series A money should let the company finish phase I trials with its imaging agent and bring a therapeutic candidate to IND-enabling studies, CEO Ravi Srinivasan told BioWorld, as the company works with a "phenomenon [that] has not been exploited so far, even though it's been well-known and well-established in the cancer field." Read More

Jounce ouch: ASCO data dump claims first victim as abstracts land

The celebrated annual release of abstracts from the American Society of Clinical Oncology (ASCO) meeting claimed an early victim Thursday as shares of Jounce Therapeutics Inc. (NASDAQ:JNCE) fell 35.2 percent, closing at $11.45 for a loss of $6.22, after analysts began sifting through the data dump and found the company's update wanting. Read More

Worldmeds wins FDA approval for opioid withdrawal drug

US Worldmeds LLC has landed the first FDA approval of a non-opioid treatment for the management of opioid withdrawal symptoms, giving U.S. doctors a tool that has long helped U.K. doctors provide relief to patients going off the powerful medicines. Read More

FDA pillories drug companies for their anticompetitive shenanigans

The shaming begins. As promised, the FDA called out drug companies by name Thursday for not playing fair. Read More

Regulatory actions for May 17, 2018

Read More

Clinical data for May 17, 2018

Read More

Regulatory front

The Centers for Medicare & Medicaid Services opened a 30-day public comment period for its national coverage analysis of chimeric antigen receptor T-cell therapy for cancers. Read More

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