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BioWorld - Monday, February 16, 2026
Home » Newsletters » BioWorld

BioWorld

Sep. 6, 2019

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Mix of opinion on Vertex deal; Sigilon coming on strong

Vertex Pharmaceuticals Inc.'s deal to take over Cambridge, Mass.-based Semma Therapeutics Inc. for $950 million in cash – thereby bringing aboard a potential cure for type 1 diabetes – may have brought to mind another Cambridge player in the space: Sigilon Therapeutics Inc., which inked a whopper deal with Eli Lilly and Co. in April of last year. Read More

Entyvio for HIV control flops in clinical trial, replication studies

Three separate research teams have failed to replicate a 2016 primate study showing that treatment with a primate version of monoclonal antibody Entyvio (vedolizumab, Takeda Pharmaceutical Co. Ltd.), led to prolonged suppression of viremia in SHIV-infected monkeys.  Read More

Led by U.S. scientists, funded by Chinese, cross-border firm Oncologie eyes both markets

BEIJING – Despite tensions between the U.S. and China, especially in the tech sector, Oncologie Inc. maintains its plans to pursue drug development in both markets. The clinical-stage startup, led by U.S. scientists and funded with Chinese capital, has stationed itself in both Boston and Shanghai to focus on developing innovative cancer therapies simultaneously in China and the U.S. Read More

LatAm: A fertile land of opportunity for biotech, but challenges abound

SAO PAULO, Brazil – The Latin America market has great potential to contribute to the global biotech sector, but it will have to overcome some big challenges that remain unaddressed, not least of which is how to bridge the gap between science and business. Read More

Latin American experts call for debate on interchangeability regulations for biosimilars

SAO PAULO, Brazil – A lack of guidelines for interchangeability of biologics in Latin America emerged as a key focus of discussion at the BIO Latin America conference this week. Read More

Other news to note

Alimera Sciences Inc., of Atlanta, said its board approved a proposal to effect a reverse stock split of its common shares to enable the company to attain the minimum $1 per share bid price requirement for continued listing on Nasdaq. The proposal is subject to stockholder approval at a special meeting expected to be called for that purpose. The company's shares (NASDAQ:ALIM) closed Thursday at 37.5 cents. Read More

Regulatory front

A proposed $69 million settlement has been reached in a lawsuit regarding Provigil (modafinil), Nuvigil (armodafinil) and generic modafinil.  Read More

Financings

Novan Inc., of Morrisville, N.C., said Aspire Capital Fund LLC committed to purchase up to $25 million of Novan's shares through a common stock purchase agreement. Read More

Clinical data for Sept. 5, 2019

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Regulatory actions for Sept. 5, 2019

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Novartis options IFM Due, pledging up to $840M for cGAS/STING programs

Just months after betting up to $1.58 billion on the drug discovery and early development chops of IFM Therapeutics LLC, Novartis AG is again investing in the Boston-based company. This time, it has agreed to pay IFM shareholders up to $840 million for an exclusive option to acquire a subsidiary they launched just months ago to develop new drugs for the treatment of inflammatory and autoimmune diseases, IFM Due (pronounced du-way) Inc. Read More

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