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Home » Newsletters » BioWorld

BioWorld

March 1, 2022

View Archived Issues
FDA approved icons and medical professional

PERSIST-ence pays off as the FDA approves CTI’s cancer treatment

After years of turbulent development that included a clinical hold, a COVID-19 stumble, a withdrawn approval application and an extended PDUFA date, the FDA has approved CTI Biopharma Corp.’s Vonjo (pacritinib) for treating the bone marrow cancer myelofibrosis. Read More

Janssen-Legend BCMA-targeting CAR T therapy crosses the line with US FDA approval

Janssen Pharmaceutical Cos. Inc. has become the second company to get a BCMA-targeting CAR T therapy to market with the approval of ciltacabtagene autoleucel for adults with relapsed or refractory multiple myeloma (MM) after four or more prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody.

Read More
Brain and encephalography

Abbvie expanding neurosci portfolio with $1B Syndesi buyout

Abbvie Inc. has paid $130 million up front to acquire Syndesi Therapeutics SA, a company working on a new mechanism to mitigate synaptic dysfunction associated with cognitive deficits. The deal includes up to $870 million in milestone payments for Syndesi's first-in-class modulators of the synaptic vesicle protein 2A, which Abbvie said could have applications across a range of neuropsychiatric and neurodegenerative disorders, such as Alzheimer's disease and major depressive disorder. Read More

US PTAB may have spoken, but CRISPR patent battle wages on

The U.S. Patent Trial and Appeal Board’s (PTAB) decision Feb. 28 that Broad Institute scientists were the first to invent the use of CRISPR/Cas9 genome editing in eukaryotic cells is just another chapter in the ongoing saga of who has patent rights to various elements of the CRISPR platform. Read More
Coronavirus-question-marks

Origin and efficacy questions mount; new MAb, protein vaccines, take the stage

Two years ago, BioWorld reported on 30 therapeutics and vaccines in development for COVID-19, about 3,000 people had died from the disease, and societal lockdowns began. Today, therapeutics and vaccines have ballooned to 1,048, deaths are at 6 million, and the world remains on edge due to highly transmissible variants and breakthrough infections. One thing remains the same: Scientists still do not know where the SARS-CoV-2 virus originated. Read More
Dollar-arrow-up.png

Teclison raises $5.9M to advance solid tumor program

Teclison Ltd. has raised $5.9 million to support further development of its lead candidate, TEC-001, an agent designed to induce tumor necrosis and enhance immune checkpoint inhibitors in solid cancers with liver metastasis. Wtt Investment Ltd., the Taiwan-based family office of the late Taiwanese banker Tsai Wan-tsai, led the financing.

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Appointments and advancements for March 1, 2022

New hires and promotions in the biopharma industry, including: 89bio, Biotheryx, Cellectar, Crinetics, Dyve, First Wave, F-star, Genmab, Ichnos, Invectys, Lycia, Mereo, Moleculin, Overland, Phoremost, Pulmatrix. Read More

Financings for March 1, 2022

Biopharmas raising money in public or private financings, including: Cosmos. Read More

Other news to note for March 1, 2022

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Acura, AD, Akari, Astrazeneca, Atara, Boehringer Ingelheim, Cantargia, Cerevel, Catalent, Dariohealth, EA, Emalex, Epizyme, ER-Kim, Genedx, Lifebit, Neurimmune, Opko, Quoin, Sanofi, Saol, Screen, TFF, Viatris. Read More

Regulatory actions for March 1, 2022

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Harbour Biomed, JW, Lexicon, Merck KGaA, Reata. Read More

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