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Home » Newsletters » BioWorld

BioWorld

May 23, 2023

View Archived Issues
RNA.png

Top VC round in 2023: Renagade breaks the RNA mold with its series A

Launching with a $300 million series A financing, Renagade Therapeutics Inc. has set out to target disease on a large scale – at every point throughout the human body where disease forms – through its RNA platform designed to deliver, code, edit and insert genetic information. The round, led by founding investors MPM Bioimpact and F2 Ventures, is the largest venture capital (VC) round for a U.S.-based biopharma company this year, and it is among the top series A rounds for the industry to date. Read More

Icosavax raises $67.8M and posts strong phase I RSV data

While pricing a $67.8 million registered direct offering, Icosavax Inc. also released positive top-line interim data from a phase I study of IVX-A12 against respiratory syncytial virus (RSV) and human metapneumovirus in older adults. Read More
Huang Baohua, founder and CEO, Coherent Biopharma

Coherent Biopharma nets $100M in financing for Bi-XDC drugs

Coherent Biopharma Co. Ltd. raised $100 million in series B and B+ financing rounds to step up its efforts to develop its bi-targeting ligand-drug conjugate (Bi-XDC) drugs and get them to market. Suzhou, China-based Coherent plans to use its newly expanded war chest to support the clinical trials of three candidates, CBP-1008, CBP-1018 and CBP-1019, as well as an IND application for CBP-8008 in China and the U.S., the company told BioWorld. Read More
Alistair Irvine, CEO, Scarlet Therapeutics

Scarlet raises seed round for therapeutic red blood cell approach

After long years of endeavor, Scarlet Therapeutics Ltd. believes it is poised to realize the potential of red blood cells (RBCs) as drug delivery vehicles. The company recently closed a seed round and is now laying the ground for its first clinical trials in which cultured and genetically engineered RBCs will be used to deliver enzyme replacement therapies in the treatment of rare inherited forms of two metabolic disorders. Read More
Ayvakit product image

Following the Blueprint for expansion-ISM: FDA says yes to widened label in rare mast-cell disease

Blueprint Medicines Corp. scored a broader label from the U.S. FDA for Ayvakit (avapritinib), which became the first approved therapy to treat adults with indolent systemic mastocytosis (ISM). Read More

Congress, states staging Act 2 of US Rx pricing reforms

When it comes to cutting health care costs in the U.S., last year’s Inflation Reduction Act, with its inflationary rebates and direct Medicare negotiations, was just Act 1. Now lawmakers, in both the House and Senate, are feverishly working on bipartisan scripts for Act 2 that go beyond biopharma’s role in drug prices to taking on pricing issues across the health care sector. Read More

Appointments and advancements for May 23, 2023

New hires and promotions in the biopharma industry, including: Bioage, Bioinvent, Calcimedica, Engimmune, Exo, G1, Life, Obsidian, Theriva. Read More

Financings for May 23, 2023

Biopharmas raising money in public or private financings, including: Agile, Athersys, Bavarian, Nordic, Cabaletta, Checkpoint, Larkspur, Navidea, Onkure, Oxurion, Smartbax, Syridex, Xbrane. Read More

In the clinic for May 23, 2023

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aiviva, Alnylam, Alpine, Anixa, Apnimed, Atyr, Bridgebio, Candel, Corium, Hanall, Hepion, Immix, Medincell, Milestone, Mink, Mirum, Neurimmune, Novartis, Novo Nordisk, Rain, Redhill, Regeneron, Salubris, Vicore. Read More

Other news to note for May 23, 2023

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: 7 Hills, ABL, Affimed, Biomed, Cohbar, Exo, Genpharm, Modex, Morphogenesis, Neoleukin, Nona, Novo Nordisk, Pathos AI, Rhythm. Read More

Regulatory actions for May 23, 2023

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: ABVC, Bioarctic, Biocryst, Centessa, Eisai, Freeline, Grunenthal, Hanx, Ideaya, Laekna, Polypid, Sangamo, Xbiotech. Read More

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