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Home » Newsletters » BioWorld

BioWorld

March 25, 2025

View Archived Issues
Heart scientific overlay

For nearly $2B, Jiangsu Hengrui licenses heart drug to Merck

In a deal that could reach nearly $2 billion, Jiangsu Hengrui Pharmaceuticals Co. Ltd. has licensed a small molecule for treating cardiovascular disease to Merck & Co. Inc., dropping the China-based company into a space with lots of competitors in varying stages of development. Read More

FDA clears new class of antibiotic with nod for GSK’s Blujepa

Ushering in a new class of antibiotics, the U.S. FDA approved GSK plc’s gepotidacin for use in uncomplicated urinary tract infections. Branded Blujepa, the oral triazaacenaphthylene bacterial topoisomerase inhibitor is indicated for treating female adults and adolescents, 12 and older. Read More
women-gyno-uterus-ovary

Mural Oncology sinks on nemvaleukin miss in ovarian cancer

Losing nearly 60% of its value, Mural Oncology plc backed away from its lead interleukin-2 (IL-2) drug, nemvaleukin alfa, in platinum-resistant ovarian cancer based on interim results showing it failed to reach significance in the overall survival primary endpoint. Read More

Hillstar launches with $67M series A to target TRBV9+ T cells

Hillstar Bio came out of stealth mode, announcing a $67 million series A financing round with investors including Droia Ventures, Frazier Life Sciences, Novo Holdings A/S and Lifearc Ventures. Read More
3D illustration of mesenchymal stem Cells

Nature Cell wins FDA breakthrough designation of Jointstem

Nature Cell Co. Ltd. won U.S. FDA breakthrough therapy designation of its autologous adipose-derived mesenchymal stem cell therapy, Jointstem, March 20, becoming the first Korean company to earn the label in the field of cell therapy. Read More
Dollar sign in light bulb on yellow background

Report shows increased pharma innovation despite rising R&D costs

The obesity market is driving pharma’s return on investment (ROI) upward, with the projected return rising to 5.9% overall in 2024, but only reaching 3.8% if GLP-1 assets are excluded. At the same time, the average cost of developing a drug continues to rise and now stands at $2.23 billion, compared to $2.12 billion in 2023, according to Deloitte’s 15th annual analysis of the ROI from pharmaceutical innovation. Read More

PhRMA takes aim at most of world for unfair trade practices

In a move that echoes tariff threats from U.S. President Donald Trump, the Pharmaceutical Research and Manufacturers of America (PhRMA) lobby is taking aim at most of the world for unfair trade practices in its special 2025 Special 301 Report to the U.S. Trade Representative. Read More
CMS logo and website

Oz hits Wyden’s wall of skepticism in Senate CMS post hearing

Mehmet Oz, the Trump administration’s pick to lead the U.S. Centers for Medicare & Medicaid Services (CMS), appeared for a second time in the Senate for the CMS administrator’s job. Read More
Immune checkpoint inhibitors illustration of PD-1, CTLA-4 and PD-L1.

Checkpoint inhibitor journey traces Chinese firms’ path to global revenue

Chinese pharmaceutical companies are making significant inroads into the global oncology market, particularly with the development and approval of immune checkpoint inhibitors. These treatments, which have shown strong efficacy in various cancer indications, are not only transforming the oncology landscape in China but are also gaining traction in high-value international markets, including the U.S. Read More

Appointments and advancements for March 25, 2025

New hires and promotions in the biopharma industry, including: Alligator, Byondis, Editas, Elicio, Harmony, Pathios, Skye, Vicero. Read More

Financings for March 25, 2025

Biopharmas raising money in public or private financings, including: Cyclacel, Geovax, Surrozen, Tempero Bio, Transcode. Read More

In the clinic for March 25, 2025

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Akeso, Aura, Cel-Sci, CG Oncology, Opthea, Ractigen, Unity. Read More

Other news to note for March 25, 2025

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: 23andMe Holding, Abbvie, Genmab, Mira, Profoundbio, Skny, Valneva. Read More

Regulatory actions for March 25, 2025

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Cstone, GSK, Junshi, Nature Cell, Sungen, Tonix. Read More

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