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BioWorld Science

Jan. 15, 1999

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Alexion commences phase IIb trial of C5 inhibitor for bypass surgery

Icos reviews recent developments at H&Q; new addition to pipeline revealed

Pharmacokinetic studies support safety of novel dental agent

North American Vaccine updates development pipeline at H&Q

Novel compounds developed at Roche for lipid disorders and fungal infections

Cardioprotective benzoylguanidines with improved properties claimed by Hoechst

Indole-based antimigraine agents in development at Allelix

Urea derivatives acting at multiple 5-HT receptor subtypes emerge from SB R&D

Agouron's new MMP inhibitors described in patent literature

Dopamine D3 antagonists for psychoses and other D3 ligands designed at SmithKline Beecham

Seretide cleared for marketing in most E.U. countries

Novel, synthetic ultrasound contrast agent for echocardiography advances to clinical trials

Polish authorities allow phase II testing of Multikine

VP22 increases the efficacy of suicide gene therapy in vivo

Amylin gears up for regulatory filing of pramlintide and presents new clinical data

Millennium and partners extend drug discovery alliances

Amylin files IND for antidiabetes drug and reports on feasibility of alternative delivery routes

Amantadine reverses adverse effects of neuroleptic drugs on sexual function in males

Restructuring and name change announced by VIMRx

Isis and Abbott establish antisense target validation partnership

Combination of lovastatin and acipimox for type II diabetes and mixed dyslipidemia

Avanir requests meeting with FDA regarding Lidakol

Rigel and Janssen enter drug discovery collaboration

Tianeptine, a 5-HT uptake enhancer, demonstrates excellent efficacy in asthma

Onyx expands ONYX-015 clinical trials in liver metastases of colorectal cancer

Synsorb Biotech establishes collaboration with Ocean for novel antibiotic therapies

FDA advisory panel recommends clarification of data for Zila's OraTest

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