Sophiris Bio Inc., of San Diego, said it completed its registered direct offering of 5.33 million common shares (or pre-funded warrants to purchase common shares) at $0.75 each. In addition, in a concurrent private placement, the company issued the investor warrants to purchase up to 5.33 million common shares with an exercise price of $0.95 per share and a five-year exercise period. The gross proceeds are approximately $4 million.