• Care Fusion (McLean, Virginia) entered into a reseller agreement with GE Healthcare (Waukesha, Wisconsin) in which GE Healthcare will offer Wireless Care-Assist in conjunction with Dinamap ProCare and Pro Series monitors to commercial hospitals nationwide. wCareAssist, which runs on a hand-held device, allows clinicians to download patient vital signs from Dinamap ProCare and Pro Series monitors into an electronic medical record (EMR) without manual transcription and without moving an entire workstation to the patient’s bedside. The application software uses barcode technology to verify patient identification information and can be programmed to perform continuous patient monitoring automatically, recording the history of the patient’s vital signs and then sending information wirelessly to an EMR.

• Collagen Matrix (Franklin Lakes, New Jersey) said it has signed an agreement with Stryker (Kalamazoo, Michigan) for the exclusive worldwide distribution of its DuraMatrix Collagen Dura Substitute Membrane. Since January 2005, DuraMatrix has been marketed by Collagen Matrix and sold through a network of independent agents and distributors in the U.S. and Europe. Effective immediately, Collagen Matrix will begin transitioning the distribution of DuraMatrix to the Stryker craniomaxillofacial sales and marketing team. The product will continue to carry the DuraMatrix trade name.

• Devon Medical Supplies (King of Prussia, Pennsylvania) has partnered with Safe Medical Solutions to launch a nationwide co-marketing effort of safety medical products. They will market the NeedleZap, a portable needle-destruction device distributed by Safe Medical Solutions, in conjunction with Devon Medical’s line of hypodermic and insulin syringes. The companies also plan to offer Devon Medical’s SafeTip syringe technology, which is under development and expected to undergo FDA review in 2Q06.

• Diomed (Andover, Massachusetts), a developer of minimally invasive medical technologies, including its EndoVenous Laser Treatment (EVLT) for varicose veins, reported the formation of a strategic marketing and educational alliance for the U.S. vein care market with SonoSite (Bothell, Washington), which focuses on hand-carried ultrasound. The three-year agreement is designed to accelerate adoption of both hand-carried ultrasound and laser-based venous ablation technologies for the diagnosis and treatment of varicose veins. The companies will offer joint physician training and educational activities.

• Implant Sciences (Wakefield, Massachusetts) reported entering into an agreement with International Brachytherapy (IBt; Seneffe, Belgium) for Implant to expand its prostate seed offering to include IBt’s polymer encapsulated palladium 103 seed. Implant will distribute IBt’s Palladium-103 seeds in the U.S. Implant said its ability to sell into the radioactive prostate seed market should be enhanced by making available the IBt Palladium-103 radioactive prostate seed in addition to its currently available Iodine-125 radioactive prostate seed.

• The Johns Hopkins University Applied Physics Laboratory (APL; Laurel, Maryland) has signed an agree- ment with Hologic (Bedford, Massachusetts), granting it exclusive, worldwide rights to the lab’s bone health analysis technology. Hologic is a provider of diagnostic imaging and digital imaging systems directed towards women’s health, including bone densitometry equipment.

• MDS Nordion (Ottawa), a developer of nuclear medicine, and Molecular Insight Pharmaceuticals (MIP; Cambridge, Massachusetts) have signed a six-year renewable contract to manufacture and supply Zemiva, a molecular imaging pharmaceutical being developed for cardiac ischemia. Zemiva, currently in clinical trials, is targeted for the emergency department setting. Zemiva is currently manufactured at MDS Nordion’s facility in Vancouver. As a result of the contract, MDS Nordion will expand its Good Manufacturing Practice (GMP) manufacturing capabilities at this facility to support the clinical program and commercial supply of Zemiva.

• Misys Healthcare Systems (Raleigh, North Carolina), which focuses on healthcare IT, reported it has entered into an Alaris Gateway Partner Certifications Program agreement with Cardinal Health (Dublin, Ohio). The agreement enables hospitals using Misys’ enterprise electronic health record solution, Misys CPR, and Cardinal Health’s wireless smart infusion information system, the Alaris Network, to transmit infusion status information, patient monitoring, alarm data and patient ID information from Alaris servers to Misys CPR via a dual-access interface.

• Zyvex (Richardson, Texas), a molecular nanotechnology company specializing in micro and nanomanufacturing, micro-electromechanical systems and nanomaterials, has selected Diabetech (Dallas) as its medical device development and commercialization partner for a wireless sensor implant targeting real-time blood glucose levels in the body. Diabetech provides the capability and patented technologies necessary to develop the patient’s hand-held device for not only displaying the glucose levels from the implant to the patient but also for automatically relaying that information in real time to GlucoDynamix, Diabetech’s clinical management system. Diabetech also will be responsible for commercializing this technology as part of its Virtual-Loop Program. The collaboration is called Project GeNI, which stands for Glucose Nanobiosensor Implant.