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BioWorld - Friday, February 20, 2026
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Home » Exercise-mimicking compound offers alternative to GLP-1 therapies
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Endocrine/metabolic

Exercise-mimicking compound offers alternative to GLP-1 therapies

June 27, 2025
By Mar de Miguel
No Comments
An experimental drug for treating diabetes and obesity has been shown to lower blood sugar levels and increase fat burning. It is a β2-adrenergic receptor (β2AR) agonist that mimics the effects of physical exercise by activating skeletal muscle metabolism. Unlike GLP-1-based treatments such as semaglutide and tirzepatide, this new compound, developed by researchers at the Karolinska Institute, Stockholm University, and the biotech company Atrogi AB, does not suppress appetite or cause muscle loss. 
BioWorld BioWorld Science Science Drug design, drug delivery and technologies Cardiovascular Endocrine/metabolic Musculoskeletal Respiratory

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