I. MODIFIED AGREEMENTS

Company*
(Country;
Symbol)

Company*
(Country;
Symbol)

Change from original agreement

Terms/Details (Date)


ML Laboratories
plc
(UK; LSE:MLB)

Maxygen Inc. (MAXY)

Maxygen gained expanded rights to Ubiquitous Chromatin Opening Element technology

Maxygen expanded its license from use in research to use in development of therapeutic proteins; terms were not disclosed (6/20)

Perfusion
Partners and
Associates Inc.
*

Cytomedix Inc. (AMEX:GTF)

They settled a patent dispute over platelet- derived therapies for treating wounds and other damaged tissue

Perfusion and affiliate Transcorporeal Inc. got a license to Cytomedix technology and will pay royalties of $250,000 and 10% of future sales (6/27)

II. TERMINATED AGREEMENTS

XOMA Ltd.
(XOMA)

Zephyr Sciences Inc.*

XOMA terminated a 2004 deal under which Zephyr gained rights to bactericidal/permeability-increasing protein-related products

XOMA said Zephyr did not meet the financing requirements of the deal, which included the lead product Neuprex; the deal called for $11M in license fees and up to $62M in milestone payments, as well as royalties on any sales (7/15)


Notes:

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

LSE = London Stock Exchange; AMEX = American Stock Exchange