Total: $701.08M

Company
(Symbol)#
(M)

Type Of
Financing

Number Of
Shares, Units
Or Warrants

Amount
Raised
(M)

Investors; Placement Agents; Details (Date)@


Acusphere
Inc.
(ACUS)

Sale of
convertible
stock

N/A

$45

Acusphere sold 900,000 shares of 6.5% convertible exchangeable preferred stock at $50 per share; it is convertible into common stock at $6.86 per share; underwriters Piper Jaffray & Co. (lead), SG Cowen & Co. and C.E. Unterberg, Towbin have an overallotment option on another 100,000 shares (2/18)

Alkermes
Inc.
(ALKS)

Private placement of notes

N/A

$170

The 7% notes due 2018 will be paid solely from manufacturing and royalty revenues from sales of Risperdal Consta, a schizophrenia drug marketed by J& J unit Janssen-Cilag (2/3)

BioBalance
Corp.
(subsidiary
of New York
Health Care Inc.;
OTC BB:BBAL)

Private placement of stock and warrants

7.9S and 3.9W

$4.9

The shares were sold at $0.62 each; warrants are exercisable at $0.78 per share; investors included Mellon HBV Alternative Strategies and Little Gem Life Sciences Fund LLC; placement agent Sterling Financial Investment Group got warrants to purchase shares equal to 15% of the offering at $0.62 per share (2/24)

BioCryst
Pharmaceuticals
Inc.
(BCRX)

Private placement of stock

4.35S

$23.9

The shares were sold from a shelf registration at $5.50 each; Leerink Swann & Co. was placement agent (2/17)

BioDelivery
Sciences
International
Inc.
(BDSI)

Convertible debt deal

N/A

$2.5

Laurus Master Fund Ltd. bought the three-year, prime-plus-2% note convertible into common stock at $3.10 per share; Laurus also got warrants to purchase up to 350,000 shares at $3.88 per share (2/23)

Cytomedix
Inc.
(OTC BB:
CYME)

Warrants and options exercise

ND

$1.4

Investors exercised about 1.1M warrants and options between Oct. 1, 2004, and Feb. 15, 2005 (2/15)

Discovery
Laboratories
Inc.
(DSCO)

Private placement of stock

5.05S

$29.1

Shares in the registered direct offering were sold at $5.76 each; SG Cowen & Co. LLC was placement agent (2/18)

DOR
BioPharma Inc.
(AMEX:DOR)

Private placement of stock and warrants

8.4S and 6.3W

$3.77

Institutional investors purchased the stock and warrants; the five-year warrants are exercisable at 101% of the closing price the day of the deal, starting 180 days after the deal's close (2/3)

Ecopia
BioSciences
Inc.
(Canada;
TSE:EIA)

Bought-deal financing

11U

C$9.9 (US$8)

Units, sold at C$0.90 each, consist of one share and one-third of a warrant; each two-year whole warrant allows for the purchase of one share at C$1.03; the underwriting syndicate was led by Desjardins Securities Inc. and included First Associates Investments Inc. and Orion Securities Inc.; the totals include their purchase of 1M units per their overallotment option (2/25)

GeneMax Corp.
(Canada; OTC
BB: GMXX)

Private placement of stock and warrants

9.3S and 4.65W

$1.4

The warrants are exercisable from $0.15 to $0.50 each, depending on the timing and other factors; finders' fees of 8% cash and 5% warrants were paid to certain brokers in the deal (2/15)

GW
Pharmaceuticals
plc
(UK; LSE:GWP)

Private placement of stock and warrants

2.03S and 0.203W

£2.5 (US$4.8)

GW's U.S. founding investor increased its stake in the company with the purchase of shares at £1.235 per share; the five-year warrants are exercisable at £1.35 per share (2/28)

MultiCell
Technologies
Inc.
(OTC BB:
MUCL)

Private placement of stock and warrants

26.67S and 26W

$4

The shares were sold at $0.15 each; 18M of the three-year warrants are exercisable at $0.20 and 8M of them at $0.30; Mercator Group Advisors LLC and Marr Group were the lead investors (2/14)

Neurologix
Inc.
(OTC BB: NRGX)

Private placement of stock and warrants

1.896S and 0.474W

$2.46

The shares were sold at $1.30 each; the five-year warrants are exercisable at $1.625 per share; Merlin Biomed Group led the financing, which was done in two closings (2/11 and 2/25)

Oncolytics
Biotech Inc.
(Canada; ONCY)

Warrants exercise

0.814S

$3.25

Investors in a June 2003 financing exercised warrants for about 0.814M shares (2/22)

Pharma-
Frontiers Corp.
(OTC BB:PFTR)

Private placement of convertible notes

N/A

$6.1

The $6.1M convertible notes will be automatically exchanged for stock if PharmaFrontiers raises $10M in a stock sale before the notes' maturity on Nov. 30, 2005 (2/14)

Protein Design
Labs Inc.
(PDLI)

Private placement of convertible notes

N/A

$250

The 2% notes due 2012 are convertible into common stock at $23.69 per share; investors have an option to purchase another $50M of the notes (2/9)

Scolr Pharma
Inc.
(AMEX:DDD)

Private placement of stock

3.75S

$15

The shares were sold at $4 each; the placement agent, Taglich Brothers, received a fee and five- year warrants to purchase up to 75,000 shares (2/8)

Tm Bioscience
Corp.
(Canada;
TSE:TMC)

Bought-deal financing

4.33S

C$9.3 (US$7.6)

The shares were sold at C$2.15 through a syndicate of underwriters led by Orion Securities Inc. and including Dlouhy Merchant Group (2/3)

Vernalis plc
(UK; VNLS)

Private placement and open offer

43.3S

£30.3 (US$57.9)

The shares were sold at 70 pence each; existing shareholders were offered five new shares for every 18 ordinary shares held (2/24)

XOMA Ltd.
(XOMA)

Private placement of convertible notes

N/A

$60

The 6.5% senior notes are convertible into common stock at an initial price of $1.87; purchasers have an option to buy up to $5M more of the notes (2/1)


Notes:

This chart does not include real estate or manufacturing plant financings.

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

Currency conversions are based on exchange rates at the time of the deal.

N/A = Not applicable; ND = Not disclosed.

AMEX = American Stock Exchange; LSE = London Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSE = Toronto Stock Exchange.