Total: $2,168.94M

Company
(Symbol)#

Type Of Financing

Number
Of
Shares, Units Or Warrants (M)

Amount Raised (M)

Investors; Placement
Agents; Details
(Date)@


Aastrom
Biosciences

Inc.
(ASTM)

Private placement of common stock

N/A

$9.5

Aastrom raised $9.5M through a private placement of common stock (7/10)

Advanced
Magnetics Inc.
(AMEX:AVM)

Private placement of common stock

1S and W

$10

Advanced Magnetics raised $10M in the private placement of 1M shares; investors also will receive warrants to purchase 261,780 shares at $15.50 per share (7/3)

AEterna
Laboratories

Inc.
(TSE:AEL)

Bought-deal financing

4.5S

C$35.6
(US
$26.2)

AEterna raised US$26.2M by selling 4.5M shares to a syndicate of underwriters, which also received an option to purchase up to an additional 1M shares; the underwriters were RBC Capital Markets, National Bank Financial Inc., Paradigm Capital Inc., Desjardins Securities Inc. and Loewen, Ondaatje, McCutcheon Ltd. (7/8)

Amylin
Pharmaceuticals
Inc.
(AMLN)

Private placement of convertible senior notes

N/A

$25

Amylin raised another $25M in its private placement of $150M of senior notes through the exercise of the overallotment option (7/18)

Avanir
Pharmaceuticals
Inc.
(AMEX:
AVN)

Private placement of common stock and warrants

N/A

$10

Avanir raised $10M through the placement of common stock to accredited investors, who also received a warrant to purchase one Class A common share for every five shares of stock purchased in the offering; ThinkEquity Partners LLC acted as the offering's placement agent (7/24)

Avant
Therapeutics

Inc.
(AVAN)

Private placement of common stock and warrants

4.4S and
W for 0.44S

$10

Avant raised $10M in a financing; Rodman & Renshaw was placement agent (7/1)

Biopure
Corp.
(BPUR)

Private placement of common stock

3.1S

$17.2

Biopure raised $17.2M with the placement of 3.1M shares to a group of investors; ThinkEquity Partners LLC acted as the offering's placement agent (7/24)

Celsion Corp.
(AMEX:CLN)

Private placement of common stock

11.9S

$5.1

Celsion raised $5.1M through the exercise of out- standing common stock purchase warrants, resulting in the issuance of about 11.9M shares (7/8)

Chiron
Corp.
(CHIR)

Private placement of convertible debentures

N/A

$450

Chiron raised about $450M by selling debentures to institutional buyers (7/25)

Columbia
Laboratories

Inc.
(AMEX:COB)

Private placement of common stock

2.2S

$26.3

Columbia raised $26.3M through the placement of 2.2M shares with institutional investors (7/24)

Cytogen
Corp.
(CYTO)

Private placement of common stock and warrants

1.2S and
W for 1.2S

$10

Cytogen raised $10M in the private placement with institutional investors (7/11)

DOR
BioPharma
Inc.
(AMEX:DOR)

Private placement of common stock and warrants

6.8S and
W for 6.8S

$5.4

DOR raised $5.4M through the placement led by OrbiMed Advisors LLC; other investors were Perceptive Life Sciences Fund, Wexford Capital, Height Capital, Eagle Advisors and A.M. Pappas & Co.; the placement agent was Paramount Capital Inc. (7/21)

DOV
Pharmaceutical
Inc.
(DOVP)

Private placement of stock and warrants

1.4S and
W for 0.393S

$15

DOV raised $15M in a private placement of stock and warrants to a group of funds managed by OrbiMed Advisors LLC (7/3)

Durect
Corp.
(DRRX)

Private placement of convertible notes

N/A

$10

The initial purchaser of $50M of Durect's 6.25% convertible notes due 2008 elected to exercise its option to purchase an additional $10M in notes (7/14)

EpiTan
Ltd.
(Australia; ASX:EPT)

Exercise of
options

N/A

A$2.5
(US
$1.7)

EpiTan raised US$1.7M through the exercise of 8.3M options (7/1)

Genetronics
Biomedical

Corp.
(AMEX:
GEB)

Private
placement of preferred stock

N/A

$8.2

Genetronics raised about $8.2M in a Series A cumulative convertible preferred stock deal; it also could receive another $7.5M in a similar Series B deal; that money was placed in escrow to be released upon an undisclosed milestone (7/16)

GTC Biothera-
peutics Inc.
(GTCB)

Private
placement of common stock and warrants

3.6S and
W for 0.9S

$9.26

GTC Biotherapeutics raised $9.26M in the placement; it would raise a total of $12.2M if all warrants are exercised (7/31)

Guilford
Pharmaceuticals
Inc.
(GLFD)

Private
placement of convertible notes

N/A

$9.3

Guilford raised another $9.3M in an offering to cover overallotments; that brings gross proceeds to $69.3M, with $60M being raised in June (7/30)

Hemispherx
Biopharma Inc.
(AMEX:HEB)

Private
placement of secured convertible debentures

N/A

$5.43

Hemispherx raised $5.43M in the placement with investors (7/14)

ICOS Corp.
(ICOS)

Private
placement of convertible subordinated notes

N/A

$28.7

ICOS raised another $28.7M through the exercise of an option on the part of the initial purchasers of $250M of its 2% convertible subordinated notes (7/16)

Incara
Pharmaceuticals
Corp.
(OTC BB:INCR)

Bridge loan
facility

N/A

$3

Incara closed on a $3M bridge loan facility (7/29)

Indevus
Pharmaceuticals
Inc.
(IDEV)

Private
placement of convertible senior notes

N/A

$60

Indevus raised $60M through the placement of notes to qualified institutional buyers (7/11)

InSite Vision
Inc.
(AMEX:
ISV)

Secured loan interim financing

N/A

$0.4

InSite Vision received a $400,000 secured loan from an investor in an interim financing (7/15)

Insmed Inc.
(INSM)

Private
placement of common stock

4.44S

$13.9

Insmed raised $13.9M in the placement with a group of institutional investors; Wells Fargo Securities LLC served as lead placement agent (7/11)

Invitrogen
Corp.
(IVGN)

Private
placement of senior convertible notes

N/A

$325

Invitrogen raised $325M worth of notes sold to institutional buyers (7/29)

Isotechnika
Inc.
(Canada;
TSE:ISA)

Private
placement of common stock

6.5S

$15

Isotechnika raised $15M in the placement; Banc of America Securities LLC served as lead placement agent, with Friedman, Billings, Ramsey & Co. Inc. acting as co-manager (7/18)

Medarex
Inc.
(MEDX)

Private
placement of convertible senior notes

N/A

$125

Medarex raised $125M in an offering to institutional buyers (7/18)

MedImmune
Inc.
(MEDI)

Private
placement of convertible senior notes

N/A

$500

MedImmune raised $500M in the private placement (7/10)

Nabi Bio-
pharma-

ceuticals

(NABI)

Private
placement of common stock

5.5S

$32.9

Nabi raised $32.9M in a private placement of 5.5M shares; Lehman Brothers Inc. was the placement agent (7/14)

Nektar
Therapeutics
(NKTR)

Private
placement of convertible subordinated notes

N/A

$10

Nektar raised another $10M when buyers exercised their overallotment option, increasing the principal amount sold to $110M; $100M was raised in June (7/30)

NexMed
Inc.
(NEXM)

Private
placement of common stock

2.9S and
W for 1S

$10.5

NexMed raised $10.5M through a private placement of about 2.9M shares; investors included The Tailwind Fund, MidSummer Capital and Viking Global Investors; investors also received warrants to purchase about 1M common shares (7/7); Nex-Med also entered an agreement for a $1.85M line of credit with GE Life Science and Technology Finance (7/30)

Northfield
Laboratories

Inc.
(NFLD)

Private
placement of common stock

1.9S

$10.6

Northfield raised $10.6M by selling 1.9M shares to accredited investors; SG Cowen Securities Corp. acted as the placement agent (7/24)

NPS Pharma-
ceuticals
Inc.
(NPSP)

Private
placement of convertible notes

N/A

$22

NPS raised an additional $22M for a total of $192M because the initial purchasers exercised their option to purchase additional notes (7/10)

Paradigm
Genetics
Inc.
(PDGM)

Debt financing agreement

N/A

--

Paradigm gained access to $7.5M in an agreement with Silicon Valley Bank, including a $5M term loan and a $2.5M revolving line of credit (7/10)

Pluristem Life
Systems Inc.

(OTC BB:PLRS)

Private
placement

N/A

$1.3

Pluristem raised a total of $1.3M in a second round (7/29)

Protein
Design
Labs
Inc.
(PDLI)

Private
placement of convertible subordinated notes

N/A

$250

Protein Design Labs raised $250M through the sale of convertible subordinated notes (7/9)

Proteome
Sciences plc

(UK; LSE:PRM)

Private
placement of common stock

N/A

£5.8
(US
$9.3)

Proteome Sciences raised US$9.3M in a private placement with institutional investors (7/2**)

Sonus Pharma-
ceuticals
Inc.
(SNUS)

Private
placement of common stock

3.9S

$13.1

Sonus raised $13.1M in a private placement of 3.9M shares to new and current institutional in- vestors (7/29)

Syn-X
Pharma
Inc.
(Canada;
TSE:SYY)

Private
placement of subordinated secured debentures

N/A

C$3
(US
$2.2)

Syn-X raised US$2.2M in the private placement that was accompanied by about 1.5M common purchase share warrants (7/10)

The Immune
Response
Corp.
(IMNR)

Exercise
of warrants

7W

$9.4

Immune Response gained $9.4M through a voluntary exercise of more than 7M Class A warrants (7/11)

Trinity
Biotech

plc
(TRIB)

Private
placement of convertible notes

N/A

$20

Trinity Biotech raised $20M after completing a private placement of 3% convertible notes due 2007 to three institutional investors (7/11)

Vasogen
Inc.
(Canada;
AMEX:VSV)

Private
placement of common stock

9.375S

$37.5

Vasogen raised $37.5M in a private placement; investors were Quest Diagnostics, WPG Farber Fund, AIG Global Investment, China Development Industrial Bank, George Weiss Associates, Knott Partners, Oakmont Corp., Straus Asset Management, Sceptre Investment Counsel and AGF Management; Needham & Co. acted as placement agent (7/3)

Viragen
Inc.
(AMEX:
VRA)

Private
placement of convertible debentures

N/A

$5.55

Viragen raised $5.55M in a financing with institutional stockholders (7/1)


Notes:

This chart does not include real estate or manufacturing plant financings.

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

@ Dates refer to the date of the press release.

** Denotes the date the item ran in BioWorld International.

N/A = Not available, applicable or reported.

AMEX = American Stock Exchange; ASX = Australian Stock Exchange; LSE = London Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSE = Toronto Stock Exchange.