Biotech Co.*
(Country;
Symbol)

Agbiotech Partner
(Country;
Symbol)

Type/Product Area

Terms/Details (Date)


Affymetrix Inc. (AFFX)

Monsanto Co. (NYSE:MON)

Custom supply agreement for Affymetrix's GeneChip technology

Monsanto will use the technology in its research to improve food quality while enhancing crop yield and reducing the need for chemical inputs (3/26)

AniGenics Inc.*

Veterinary Infectious Disease Organization, the University of Saskatchewan, the University of British Columbia, Simon Fraser University and Inimex Pharmaceuticals Inc.* (Canada)

Collaborative research program sponsored by Genome Canada

The program will begin in the summer and focus on infectious disease genomics of cattle and poultry; it is a three-year, C$27M (US$17.5M) program (5/24)

Athenix Corp.*

AgraQuest Inc.*

Agreement in which the companies will provide each other access to their respective microbial collections

AgraQuest focuses on environmentally friendly natural pest management products; Athenix is developing genetic solutions for selected industrial uses (3/6)

Celera Genomics Group (NYSE: CRA)

MetaMorphix Inc.*

Agreement for the sale of Celera's AgGen animal genomics and genotyping business to MetaMorphix

MetaMorphix also received a subscription to the Celera Discovery System and it intends to commercialize products derived from Celera's livestock genomic databases; Celera acquired a minority interest in MetaMorphix and is entitled to share future revenue generated from products based on Celera's livestock databases (3/4)

Ceres Inc.*

Monsanto Co. (NYSE:MON)

Agreement to improve agricultural harvests

Monsanto acquires rights to Ceres' technologies for certain undisclosed crops and applications; Ceres will receive payments over several years, and could see further payments; Monsanto will fund the program, and has made an investment in Ceres; the deal is worth up to $137M, not including royalties (4/2)

Codexis Inc. (subsidiary of Maxygen Inc.; MAXY)

Cargill Dow LLC*

Agreement focused on the development of a synthesis for a raw material for Cargill's NatureWorks polylactide

Codexis will apply its protein modification technologies toward creating a natural-based process for the production of lactic acid (4/17)

ExonHit Therapeutics SA* (France)

Roche Applied Science (unit of Roche Diagnostics of F. Hoffmann-La Roche Ltd.; Switzerland)

Research contract agreement to develop tests for bovine spongiform encephalopathy in living animals

The companies will combine their technologies and work to identify RNA signatures in bovine blood that correlate to BSE infection; they intend to develop a BSE test within 12 months (5/13)

Hyseq Pharma-
ceuticals
Inc. (HYSQ)

BASF Plant Science LLC (unit of BASF AG; Germany; NYSE:BF; FSE:BAS; LSE:BFA)

Modified agreement in which Hyseq is accelerating the completion of a collaboration that was supposed to continue until mid-2003 and called for Hyseq to receive up to $60M for providing gene sequencing on 12 plant species

To date, Hyseq has worked on eight plant species and received $40M from the collaboration; the new arrangement frees Hyseq from doing any additional species (5/15)

InterLink Bio-
technologies
LLC*

Fort Dodge Animal Health (division of Wyeth; NYSE: WYE)

Collaborative research agreement in which Interlink will provide access to its libraries of natural products to screen for new antiparasitic compounds for animal use

Fort Dodge will pay access fees, milestone payments and royalties for use in the field of animal health; Interlink has rights for use in the field of crop protection, for which Fort Dodge would receive royalties (5/6)

Lynx Thera-
peutics
Inc. (LYNX)

Aventis CropScience GmbH (unit of Aventis SA; France; NYSE:AVE)

Agreement to jointly develop and commercialize an assay based on Lynx's bead-based technologies

The companies will jointly own the assay; Lynx will manufacture and sell the services or products based on the assay technology, and will pay royalties to Aventis; Lynx also will perform genomics discovery services for Aventis (4/1)

MaxyAg Inc. (unit of Maxygen Inc.; MAXY)

Delta and Pine Land Co. (NYSE:DLP)

Agreement to form DeltaMax Cotton LLC to create, develop and commercialize genetically enhanced traits for the cotton seed market

Each company will own 50% of the venture; DeltaMax will contract research and development activities to MaxyAg, D&PL and third parties when appropriate (5/28)

Naturol Inc. (subsidiary of Coronado Explorations Ltd.; OTC BB: COOX)

Prince Edward Island Food Technology Centre (Canada)

Research project partnership to extract taxanes from Canadian yew trees

The recent commissioning of a Naturol extract processing plant on a pilot scale at the center has made the project possible (3/6)


Notes:

This chart contains information on new and revised corporate agreements in agricultural biotechnology covering the time between 12/27/01 and 5/30/02.

* Private companies are indicated with an asterisk.

Unless otherwise indicated, shares are traded on the Nasdaq exchange.

FSE = Frankfurt Stock Exchange; LSE = London Stock Exchange; NYSE = New York Stock Exchange; OTC BB = Over the Counter Bulletin Board

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