Biotech Co.* (Symbol)

Agbiotech Partner (Country/Symbol)

Type/Product Area

Disclosed Funding (M)

Terms/Details (Date)

Agritope Inc. (AGTO)

Rohm and Haas Co. (NYSE:ROH)

Technology development and marketing agreement to create a new plant transformation marker selection system for use in agricultural biotechnology

ND

Once developed, the system will permit the rapid creation of improved plant varieties; both companies will conduct research and any royalties will be shared equally; Rohm and Haas will manufacture the ligand and market the transformation marker system (9/14)

Akkadix Corp.*

Pangene Corp.*

Licensing agreement for Pangene's Homologous Recombination and other related technologies

ND

Akkadix has been granted a license to technologies for commercial use in the plant science field; Pangene also has been granted a nonexclusive cross-license to Akkadix's bioinformatics technology (9/13)

Akkadix Corp.*

Samuel Roberts Noble Foundation

Research project for improving the quality and digestibility of forage crops

ND

Initial target for the project is alfalfa; Akkadix will provide research support and its bioinformatics to identify genes in return for access to resulting developments (11/29)

Aurora Biosciences Corp. (ABSC)

Ceres Inc.*

License agreement for Aurora's fluorescent protein technology for use in agricultural applications

ND

Ceres was granted nonexclusive rights to use the technology for in vitro and in vivo research and development activities and to provide services to third parties; the multi-year agreement includes an up-front technology access fee, annual license fees and royalties; Aurora also has an option to acquire equity in Ceres (10/3)

Ceres Inc.*

The Institute for Genomic Research

Collaboration to identify the structure of genes and their encoded proteins in the chromosomes of a plant species

ND

Parties will focus on the plant species Arabidopsis thaliana (12/19)

Dow AgroSciences LLC (subsidiary of Dow Chemical Co.; NYSE:DOW)

Boyce Thompson Institute for Plant Research

Multiyear research and collaboration agreement to evaluate and develop plant-derived veterinary biologics

ND

Dow and the Boyce Thompson Institute signed the agreement under which scientists will work to accelerate the development and commercialization of plant-derived vaccines for the animal health industry (11/2)

Encore Technologies*

Prophyta* (Germany)

Exclusive distribution and marketing agreement for Contans WG

ND

Encore will distribute and market Contans WG, a biological fungicide, developed by Prophyta, which controls Sclerotinia diseases in the soil (11/13)

EraGen Biosciences*

Novartis Agricultural Discovery Institute Inc. (NYSE:NVS)

Collaboration for high-throughput genotyping

ND

EraGen and Novartis will collaborate with Novartis to provide AEGIS (an expanded genetic information system) technology for genotyping; the goal is to accelerate the research and development of methods to protect and improve crops (11/2)

Exelixis Inc. (EXEL)

Dow AgroSciences LLC (subsidiary of Dow Chemical Co.; NYSE:DOW)

Three-year collaboration to develop fungicides and herbicides for crop protection

ND

Exelixis will identify and validate targets and format screening assays that will be used by Dow; Dow will provide research funding, as well as milestone payments and royalties (7/11)

GeneData AG* (Switzerland)

Zeneca Agrochemicals (unit of AstraZeneca plc; UK; NYSE:AZN)

License agreement for gene expression software

ND

Zeneca will use GeneData's GD Expressionist software for analysis of gene expression array data, supporting development of crop protection products, controlling principal weeds, pests and major crop diseases (8/8)

Geron Corp. (GERN)

AviGenics Inc.* and Origen Therapeutics Inc.*

Licensing agreement for nuclear transfer technology

ND

AviGenics and Origen Therapeutics obtained option rights to license on a nonexclusive, worldwide basis Geron's nuclear transfer technology to generate cloned poultry; Geron will receive equity in each company; terms for the licenses include additional equity and a share in future revenues generated from products under the licenses (12/20)

Oxford Molecular Group plc (UK; LSE:OMG)

Zeneca Agrochemicals (unit of AstraZeneca plc; UK; NYSE:AZN)

Software agreement

ND

Zeneca purchased Oxford's RS3 Discovery and Diamond Discovery software; companies will work together to develop an advanced combinatorial chemistry software system (8/10)

Protherics plc (UK; LSE:PTI)

Zeneca Agrochemicals (unit of AstraZeneca plc; UK; NYSE:AZN) and Cytopia Pty Ltd.* (Australia)

Agreement for Protherics' Dock Crunch virtual screening service

US$.25

Protherics will provide its services to both companies; the contracts are worth US$250,000 (11/1**)

Rosetta Inpharmatics Inc. (RSTA)

Monsanto Co. (NYSE:MON)

Converted pilot agreement to a full-scale, three-year collaboration to develop better crops

$15

Monsanto will pay Rosetta $15M over three years for the delivery of gene expression information; Rosetta has the potential to receive future payments, including royalties (11/28)

Notes:

This chart contains information on new corporate agreements in agricultural biotechnology covering the time between 7/1/00 and 12/20/00; stocks trade on Nasdaq unless otherwise noted.

AMEX = American Stock Exchange; LSE = London Stock Exchange

ND = Not disclosed, reported and/or available

* Private companies are indicated with an asterisk.

** Denotes the date the item ran in BioWorld International