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BioWorld - Sunday, January 25, 2026
Home » LRRK2 inhibitors

Articles Tagged with ''LRRK2 inhibitors''

Neurology/Psychiatric

Innovstone Therapeutics divulges new LRRK2 inhibitors for Parkinson’s disease

Dec. 20, 2023
Innovstone Therapeutics Ltd. has synthesized aromatic heterocyclic compounds acting as leucine-rich repeat kinase 2 (LRRK2; Dardarin) inhibitors reported to be useful for the treatment of Parkinson’s disease.
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Neurology/Psychiatric

Brenig Therapeutics patents new LRRK2 inhibitors for Parkinson’s disease

Nov. 3, 2023
Brenig Therapeutics Inc. has disclosed leucine-rich repeat kinase 2 (LRRK2; dardarin) inhibitors reported to be useful for the treatment of Parkinson’s disease, among others.
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Neurology/Psychiatric

Whanin Pharmaceutical patents new LRRK2 inhibitors

July 13, 2023
Whanin Pharmaceutical Co. Ltd. has disclosed macrocyclic pyrimidine derivatives acting as...
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Neurology/Psychiatric

Medshine Discovery presents new LRRK2 inhibitors for Parkinson’s disease

May 29, 2023
Medshine Discovery Inc. has divulged azaspiro compounds acting as leucine-rich repeat kinase 2 (LRRK2; dardarin) inhibitors reported to be useful for the treatment of Parkinson’s disease.
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Neurology/Psychiatric

Lundbeck and Vernalis jointly patent LRRK2 inhibitors

May 22, 2023
H. Lundbeck A/S and Vernalis (R&D) Ltd. have jointly patented leucine-rich repeat kinase 2 (LRRK2; Dardarin) and/or LRRK2 mutant inhibitors reported to be useful for the treatment of Lewy body dementia, multiple system atrophy and Parkinson’s disease.
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Neurology/Psychiatric

Merck Sharp & Dohme patents LRRK2 inhibitors for Parkinson’s disease

April 27, 2023
Leucine-rich repeat kinase 2 (LRRK2; Dardarin) inhibitors have been detailed in a recent Merck Sharp & Dohme Corp. patent and reported to be useful for the treatment of Parkinson’s disease, among others.
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Brain illustration
Neurology/Psychiatric

Merck & Co. reports CNS-penetrant macrocyclic LRRK2 inhibitor for Parkinson’s disease

April 3, 2023
Merck & Co. Inc. presented the discovery, SAR-driven optimization and characterization of leucine-rich...
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Neurology/Psychiatric

New LRRK2 inhibitors presented by Sanofi

Jan. 13, 2023
Sanofi SA has divulged substituted pyrrolo[2,3-d]pyrimidines acting as leucine-rich repeat kinase 2 (LRRK2; dardarin and/or G2019S mutant) inhibitors reported to be useful for the treatment of Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, Lewy body dementia, progressive supranuclear palsy, frontotemporal dementia and Niemann-Pick disease.
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Cancer

Standigm identifies new LRRK2 inhibitors

Nov. 3, 2022
Standigm Inc. has disclosed leucine-rich repeat kinase 2 (LRRK2), particularly LRRK2 G2019S mutant, inhibitors reported to be useful for the treatment of cancer, neurodegeneration, rheumatoid arthritis, tuberculosis, axial spondyloarthritis, radiographic (ankylosing spondylitis), Crohn's disease and dyskinesia.
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Neurology/Psychiatric

Standigm presents new LRRK2 (G2019S mutant) inhibitors

Oct. 21, 2022
Standigm Inc. has identified new phenylaminopyrimidine leucine-rich repeat kinase 2 (LRRK2; Dardarin) (G2019S mutant) inhibitors reported to be useful for the treatment neurodegeneration, among other disorders.
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