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BioWorld - Thursday, June 8, 2023
Home » Topics » Deals and M&A » License

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Cancer

Bayer signs license agreement for Cedilla's cyclinE1/CDK2 complex inhibitors

June 2, 2023
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Bayer AG and Cedilla Therapeutics Inc. have entered into an exclusive license agreement to develop and commercialize Cedilla Therapeutics' cyclinE1/cyclin dependent kinase 2 (CDK2) complex inhibitors, which selectively address oncogenic drivers.
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Cancer

Impact Therapeutics and Eikon collaborate to develop and commercialize PARP1 selective inhibitors

June 2, 2023
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Impact Therapeutics Inc. and Eikon Therapeutics...
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Close up of man's eye
Ocular

4DMT acquires rights to sCFH as payload for 4D-175 for geographic atrophy

April 25, 2023
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4D Molecular Therapeutics (4DMT) Inc. has acquired the rights and know-how for short-form human complement factor H (sCFH) from...
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3D illustration of nanobubbles as drug delivery technology.
Drug Design, Drug Delivery & Technologies

Sonothera licenses Bracco Imaging’s microbubble technology for ultrasound-guided nonviral gene therapy platform

April 14, 2023
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Bracco Imaging SpA and Sonothera Inc. have entered into an agreement under which Bracco Imaging will provide its cutting-edge gas-filled microbubbles technology platform to Sonothera for use in the development of its novel, ultrasound-guided nonviral gene therapy platform.
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Neurology/Psychiatric

Biohaven licenses ex-China rights to Highlightll’s TYK2/JAK1 inhibitor for neurological disorders

March 23, 2023
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Biohaven Ltd. has acquired global rights, excluding China regions, from Hangzhou Highlightll Pharmaceutical Co. Ltd. for TLL-041, now designated BHV-8000, an oral, brain-penetrant, highly selective, dual TYK2/JAK1 inhibitor, for neurological disorders.
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CAR T cell attacking cancer cells
Immuno-oncology

Coimmune exercises option to license IL-18 armored CAR technology from MSK

March 21, 2023
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Coimmune Inc. has exercised its option to obtain an exclusive license to IL-18 armored chimeric antigen receptor (CAR) technology under a prior agreement with Memorial Sloan Kettering Cancer Center (MSK). The company plans to couple the technology with allogeneic cytokine induced killer (CIK) cells to launch the clinical development of CMN-008 (armored CAR-CIK cells), with CD19 as the initial target in B-cell malignancies.
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Test tubes, dropper and capsules
Musculoskeletal

Gilead exercises option to license oral IRAK-4 degrader under collaboration with Nurix

March 21, 2023
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Gilead Sciences Inc. has exercised its option to exclusively license Nurix Therapeutics Inc.'s investigational targeted protein degrader molecule NX-0479, now designated GS-6791. This bivalent degrader is the first development candidate resulting from the companies' collaboration to discover, develop and commercialize up to five innovative targeted protein degradation therapies.
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Antibodies attacking cancer cell
Immuno-oncology

Eureka Therapeutics licenses antibody targeting mesothelin from NCI

March 15, 2023
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Eureka Therapeutics Inc. has entered into a license agreement with the National Cancer Institute (NCI) to develop and commercialize a novel antibody targeting mesothelin (MSLN) in combination with Eureka's proprietary Artemis T-cell receptor platform.
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Needle syringe with a vaccine vial.
Immune

Modex Therapeutics enters license and collaboration with Merck & Co. for EBV vaccine candidate MDX-2201

March 9, 2023
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Modex Therapeutics Inc., an Opko Health Inc. company, has entered into an exclusive worldwide license and collaboration agreement with Merck & Co. Inc., for the development of MDX-2201, Modex's preclinical nanoparticle vaccine candidate targeting Epstein-Barr virus (EBV).
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Scientist with vial
Inflammatory

Coya gains rights to develop COYA-301 for autoimmune diseases

Feb. 16, 2023
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Coya Therapeutics Inc. has announced expansion of its exclusive worldwide rights for the development and commercialization of COYA-301, the company's low-dose IL-2 subcutaneous administration product candidate. COYA-301 is intended to enhance regulatory T-cell (Treg) function in vivo to treat the systemic neuro-inflammation underlying certain autoimmune and neurodegenerative diseases.
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