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BioWorld - Monday, December 29, 2025
Home » Topics » Asia-Pacific » China

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Brii Bio shares interim data on antibody combination therapy for SARS-CoV-2

Oct. 12, 2021
By David Ho
Brii Biosciences Ltd. shared interim data from a phase III trial of its neutralizing monoclonal antibody (mAb) combination therapy for SARS-CoV-2, BRII-196 and BRII-198, that showed a 78% reduction in the risk of hospitalization or death in patients receiving single dose of the cocktail.
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Third ADC candidate with Synaffix’s tech enters clinic as Miracogen kicks off phase I

Oct. 8, 2021
By David Ho
It looks like Shanghai Miracogen Inc.’s antibody-drug conjugate (ADC) partnership with Synaffix BV is paying off as MRG-004A, an ADC designed to treat solid tumors, has entered a U.S. phase I/II trial to treat solid tumors.
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Brii Bio shares interim data on antibody combination therapy for SARS-CoV-2

Oct. 6, 2021
By David Ho
Brii Biosciences Ltd. shared interim data from a phase III trial of its neutralizing monoclonal antibody (mAb) combination therapy for SARS-CoV-2, BRII-196 and BRII-198, that showed a 78% reduction in the risk of hospitalization or death in patients receiving single dose of the cocktail.
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CBMG’s facility in Shanghai

CBMG bags $120M in its first financing since going private, funds to benefit CAR T candidates

Oct. 5, 2021
By Gina Lee
Cell therapy developer Cellular Biomedicine Group Inc. (CBMG) completed a $120 million series A financing, its first since becoming a private company. The funds will benefit the U.S. and China-based firm’s CAR T pipeline.
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Colonoscopy illustration showing endoscope, polyps in colon

Independent study confirms AI-assisted colonoscopies reduce rate of missed lesions

Sep. 30, 2021
By David Ho
Shanghai Wision AI Co. Ltd. (Wision AI) has shared positive data from a first-of-its-kind study on the use of artificial intelligence (AI) computer-aided polyp detection (CADe) system during colorectal cancer screening in a U.S. patient population. Published in the journal Clinical Gastroenterology and Hepatology, it marks the world’s first external independent randomized controlled trial of AI in the medical field conducted in the U.S.
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CBMG’s facility in Shanghai

CBMG bags $120M in its first financing since going private, funds to benefit CAR T candidates

Sep. 30, 2021
By Gina Lee
Cell therapy developer Cellular Biomedicine Group Inc. (CBMG) completed a $120 million series A financing, its first since becoming a private company. The funds will benefit the U.S. and China-based firm’s CAR T pipeline, and the round was jointly led by Astrazeneca-CICC Fund, Sequoia Capital China and Yunfeng Capital. Existing investors including GIC Private Ltd. (formerly Government of Singapore Investment Corp.) and TF Capital also took part.
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Skin irritation on hands

Union strikes $267M deal with Innovent to develop Otezla challenger in China

Sep. 28, 2021
By Richard Staines
Denmark’s Union Therapeutics A/S has begun a strategic collaboration with Innovent Biologics Inc. over orismilast, a next-generation oral PDE4 inhibitor for inflammatory dermatology conditions that could compete directly with Amgen Inc.’s psoriasis blockbuster, Otezla (apremilast). At the same time, the company is looking for partners in the medium term to develop the drug in the rest of the world as it bids to take on Amgen and other dermatology players such as Bristol-Myers Squibb Co.
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Lung cancer illustration

Cstone presents positive phase III data of sugemalimab for NSCLC

Sep. 28, 2021
By Doris Yu
Cstone Pharmaceuticals Co. Ltd. released positive data from the phase III trial, Gemstone-302, of sugemalimab plus chemotherapy for the first-line treatment of patients with stage IV squamous and non-squamous non-small cell lung cancer.
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FDA accepts Beigene’s first filing outside China; BLA seeks nod for anti-PD-1 tislelizumab

Sep. 21, 2021
By Doris Yu
The FDA has accepted for review Novartis AG and Beigene Ltd.’s BLA filing for the anti-PD-1 monoclonal antibody tislelizumab.
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Chinese flag

New law for off-label drug use passed in China

Sep. 21, 2021
By David Ho and Gina Lee
A new law in China will grant physicians the right to use off-label drugs, giving clearer definition to a gray area and lending hope that it could benefit pharma companies.
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