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BioWorld - Sunday, January 25, 2026
Home » Topics » Regulatory » Patents

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Asia focused map inside light bulb
The year in review

Big pharma taps fast Asia innovation in search of next Keytruda

Dec. 23, 2025
By Marian (YoonJee) Chu
No Comments
Speed and innovation from Asia Pacific’s (APAC) biotechnology sector had big pharma scouring the region for the next oncology heir to Keytruda (pembrolizumab), Merck & Co. Inc.’s reigning blockbuster cancer drug.
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Cancer

Shandong Simcere Medgenn Bio-Pharmaceutical discovers new CDK4/cyclin D1 inhibitors

Dec. 23, 2025
No Comments
Shandong Simcere Medgenn Bio-Pharmaceutical Co. Ltd. has described CDK4/cyclin D1 inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

New NLRP3 inhibitors disclosed in Neushen Therapeutics patent

Dec. 23, 2025
Neushen Therapeutics Inc. has divulged NLRP3 inhibitors reported to be useful for the treatment of neurodegeneration.
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Cancer

Laekna Pharmaceutical describes new WRN inhibitors

Dec. 23, 2025
Laekna Pharmaceutical Ningbo Co. Ltd. has identified Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Xianxiang Medical Technology divulges new EGFR degradation inducers

Dec. 23, 2025
Shanghai Xianxiang Medical Technology Co. Ltd. has synthesized proteolysis targeting chimera (PROTAC) compounds comprising a cereblon (CRBN)-binding moiety coupled to an EGFR (HER1; erbB1) mutant-targeting moiety through a linker reported to be useful for the treatment of cancer.
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Cancer

Hangzhou Zhongmei Huadong Pharmaceutical patents new camptothecin derivatives

Dec. 23, 2025
Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. has disclosed camptothecin derivatives reported to be useful for the treatment of cancer.
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Immuno-oncology

Jiangsu Simcere Biologics discovers new bispecific ADCs

Dec. 22, 2025
Jiangsu Simcere Biologics Co. Ltd. has described bispecific antibody-drug conjugates (ADC) comprising a bispecific human antibody targeting hepatocyte growth factor receptor (HGFR; MET) and epidermal growth factor receptor (EGFR; HER1; erbB1), covalently linked to a camptothecin derivative through a linker reported to be useful for the treatment of cancer.
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Cancer

New TEAD inhibitors disclosed in Signet Therapeutics patent

Dec. 22, 2025
Signet Therapeutics Co. Ltd. has divulged transcriptional enhancer factor (TEAD) inhibitors reported to be useful for the treatment of cancer, metabolic disorders, inflammatory disorders and neurodegeneration.
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Endocrine/metabolic

Aché Laboratórios Farmacêuticos describes new SGLT-1, SGLT-2 and DPP4 inhibitors

Dec. 22, 2025
Aché Laboratórios Farmacêuticos SA has identified compounds acting as sodium/glucose cotransporter 1 (SGLT-1), SGLT-2 and dipeptidyl peptidase 4 (DPP4; CD26) inhibitors reported to be useful for the treatment of cardiovascular, renal and metabolic diseases.
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Cancer

Laekna Pharmaceutical divulges new PI3Kα inhibitors

Dec. 22, 2025
Laekna Pharmaceutical Ningbo Co. Ltd. has synthesized compounds acting as phosphatidylinositol 3-kinase α (PI3Kα) inhibitors reported to be useful for the treatment of cancer.
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