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BioWorld - Sunday, May 22, 2022
Home » Topics » Infection » Coronavirus

Coronavirus
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Vaxxas HD-MAP vaccine application

COVID-19 vaccines R&D remains robust, diverse

April 22, 2022
By Jennifer Boggs
No Comments
By January 2022, 12 billion COVID-19 vaccine doses had been manufactured and, to date, roughly 20 vaccines have received either full approval or emergency use authorization in countries around the world. In places such as Europe and the U.S., most of the people who want vaccinations have gotten their jabs. And the vaccines continue to show efficacy, with the latest CDC data showing consistently less risk for testing positive for COVID-19 or dying from the infection for those who are vaccinated and boostered. Yet the development of new COVID-19 vaccines remains surprisingly robust, with BioWorld tracking 258, the majority of which are in preclinical development.
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Regulatory actions for April 22, 2022

April 22, 2022
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Ampio, Dragon Boat, Hansa, Moleculin, Nrx, Otsuka, Tvardi, Vertex, Zambon.
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Other news to note for April 22, 2022

April 22, 2022
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Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Alzecure, Arev, Celsion, Codiak, Gilead, ICER, Immune-Onc, Janssen, Legend, Pfizer, Sanofi, Terran, Vallon.
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In the clinic for April 22, 2022

April 22, 2022
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Clinical updates, including trial initiations, enrollment status and data readouts and publications: Adiso, Astrazeneca, Epicentrix, Maat, Novavax, Orasis, Servier.
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Evusheld carton and vials

Full data published on Evusheld, Astrazeneca’s ‘last MAb standing’ in COVID-19

April 21, 2022
By Randy Osborne
No Comments
Astrazeneca plc led the handful of firms rolling out COVID-19-related news, as the company said detailed results from the Provent phase III pre-exposure prophylaxis (prevention) trial with Evusheld (tixagevimab and cilgavimab), were published in the New England Journal of Medicine, the “culmination of about 19 months of pretty intensive work,” said Mark Esser, vice president of microbial sciences.
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Regulatory actions for April 21, 2022

April 21, 2022
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Regulatory snapshots, including global submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Clarius Mobile Health.
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Other news to note for April 21, 2022

April 21, 2022
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Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Aim Immunotech, Biogen, Blue Water Vaccines, Humanigen, Immvira, Roche, Samsung Bioepis, Selva, Sihuan Pharma, Tonix, Xortx, Xuansheng Pharma.
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In the clinic for April 21, 2022

April 21, 2022
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Clinical updates, including trial initiations, enrollment status and data readouts and publications: Arcturus, Bavarian Nordic, Clover, Fibrogen, Navidea, Otonomy, Snipr, Trevena, Ultragenyx, Windtree.
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US booster study next after Arcturus’ self-amplifying mRNA COVID-19 vaccine hits endpoints

April 20, 2022
By Jennifer Boggs
No Comments
Arcturus Therapeutics Holdings Inc. reported that ARCT-154, its self-amplifying mRNA COVID-19 vaccine, showed efficacy of 55% against infection and 95% efficacy against severe disease, meeting the primary and key secondary endpoints of the ongoing phase I/II/III trial. While the company’s stock (NASDAQ:ARCT) regained much of its initial 25% drop to close the day, investors continue to await further data to determine where Arcturus’ vaccine will fit in with available COVID-19 vaccines.
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Regulatory actions for April 20, 2022

April 20, 2022
No Comments
Regulatory snapshots, including global submissions and approvals, clinical trial approvals and other regulatory decisions and designations: The Orthopaedic Implant Company, Zeiss.
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