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BioWorld - Monday, December 8, 2025
Home » Keywords » DHX9 inhibitors

Items Tagged with 'DHX9 inhibitors'

ARTICLES

Cancer

Accent Therapeutics discovers new DHX9 inhibitors

March 6, 2025
Accent Therapeutics Inc. has described ATP-dependent RNA helicase A (DHX9) inhibitors reported to be useful for the treatment of cancer.
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Colorectal cancer 3D illustration
Cancer

DHX9 inhibition as strategy against MSI-H/dMMR colorectal cancer

Feb. 20, 2025
Elevated expression of DHX9 has been reported in multiple cancer types and it is associated with poor prognosis. In a recently published study, researchers from Accent Therapeutics Inc. evaluated the role of DHX9 in cancer using the tool compound ATX-968, designed as a potent and selective small-molecule inhibitor of DHX9.
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Cancer

Accent Therapeutics’ ATX-559 cleared to enter clinic

Oct. 25, 2024
Accent Therapeutics Inc. has gained IND clearance from the FDA for ATX-559, a first-in-class DHX9 inhibitor.
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Illustration of enzyme wrapped around double helix
Cancer

Accent closes series C financing to advance cancer programs

Jan. 26, 2024
Accent Therapeutics Inc. has completed a $75 million series C financing to support progression of its lead programs through early clinical development.
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Cancer

Accent Therapeutics describes DHX9 inhibitors for cancer

Sep. 12, 2023
ATP-dependent RNA helicase A (DHX9) inhibitors have been reported in an Accent Therapeutics Inc. patent as potentially useful for the treatment of cancer.
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Human colon cancer cells.
Cancer

DHX9 inhibitor ATX-968 induces tumor regression in mice with colorectal cancer

April 19, 2023
DEAH box protein 9 (DHX9) is an RNA helicase...
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