Serine/threonine-protein kinase PLK4 (Polo-like kinase 4) has emerged as an attractive therapeutic target in prostate cancer, since it plays crucial roles in cell cycle regulation and tumor progression. Investigators from 2nd Affiliated Hospital of Wenzhou Medical University have prepared and tested the PLK4 inhibitor NL-13 for the potential treatment of prostate cancer.
Second Affiliated Hospital of Wenzhou Medical University investigators have assessed the functions of FBXO28 on proliferation, migration and invasion in ovarian cancer.
